MX2022011408A - Produccion de proteina recombinante en insectos. - Google Patents

Produccion de proteina recombinante en insectos.

Info

Publication number
MX2022011408A
MX2022011408A MX2022011408A MX2022011408A MX2022011408A MX 2022011408 A MX2022011408 A MX 2022011408A MX 2022011408 A MX2022011408 A MX 2022011408A MX 2022011408 A MX2022011408 A MX 2022011408A MX 2022011408 A MX2022011408 A MX 2022011408A
Authority
MX
Mexico
Prior art keywords
insects
recombinant protein
protein production
vaccine
peptide
Prior art date
Application number
MX2022011408A
Other languages
English (en)
Inventor
Mahmoud Eljendy
Abdulaziz Elgammal
Ahmed Adel
Rana Hashish
Youssef Madbouly
Ahmed Marouf
Original Assignee
Proteinea Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proteinea Inc filed Critical Proteinea Inc
Publication of MX2022011408A publication Critical patent/MX2022011408A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
    • A01K67/0333—Genetically modified invertebrates, e.g. transgenic, polyploid
    • A01K67/0337—Genetically modified Arthropods
    • A01K67/0339—Genetically modified insects, e.g. Drosophila melanogaster, medfly
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/20—Animal model comprising regulated expression system
    • A01K2217/203—Animal model comprising inducible/conditional expression system, e.g. hormones, tet
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/70—Invertebrates
    • A01K2227/706—Insects, e.g. Drosophila melanogaster, medfly
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C12N2015/8518—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic expressing industrially exogenous proteins, e.g. for pharmaceutical use, human insulin, blood factors, immunoglobulins, pseudoparticles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/90—Vectors containing a transposable element

Abstract

La presente descripción se refiere al campo de la producción y el procesamiento a escala comercial de composiciones farmacéuticas líquidas o sólidas derivadas de insectos, en donde las composiciones incluyen una proteína, una vacuna, un anticuerpo, un péptido o un producto químico recombinante purificado. También se describen sistemas y métodos para producir los insectos y una proteína recombinante, una vacuna, un anticuerpo, un péptido, un insecticida, un fungicida o un producto químico purificado derivado de insectos dentro de un biorreactor.
MX2022011408A 2020-03-15 2021-03-15 Produccion de proteina recombinante en insectos. MX2022011408A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062989725P 2020-03-15 2020-03-15
PCT/US2021/022389 WO2021188445A1 (en) 2020-03-15 2021-03-15 Recombinant protein production in insects

Publications (1)

Publication Number Publication Date
MX2022011408A true MX2022011408A (es) 2022-12-15

Family

ID=75340302

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022011408A MX2022011408A (es) 2020-03-15 2021-03-15 Produccion de proteina recombinante en insectos.

Country Status (11)

Country Link
US (1) US20230172175A1 (es)
EP (1) EP4120829A1 (es)
JP (1) JP2023517779A (es)
KR (1) KR20220155584A (es)
CN (1) CN115334876A (es)
AU (1) AU2021237476A1 (es)
BR (1) BR112022018442A2 (es)
CA (1) CA3171935A1 (es)
IL (1) IL296417A (es)
MX (1) MX2022011408A (es)
WO (1) WO2021188445A1 (es)

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015694A1 (en) 1991-03-08 1992-09-17 The Salk Institute For Biological Studies Flp-mediated gene modification in mammalian cells, and compositions and cells useful therefor
US5840865A (en) 1992-09-14 1998-11-24 Institute Of Molecular Biology And Biotechnology/Forth Eukaryotic transposable element
US5527695A (en) 1993-01-29 1996-06-18 Purdue Research Foundation Controlled modification of eukaryotic genomes
US5919676A (en) 1993-06-24 1999-07-06 Advec, Inc. Adenoviral vector system comprising Cre-loxP recombination
US5454894A (en) 1994-03-30 1995-10-03 The Goodyear Tire & Rubber Company Apparatus for producing tire with injection molded white sidewall
US5614398A (en) 1994-11-18 1997-03-25 The University Of Maryland Biotechnology Institute Gene transfer system for insects
US6091001A (en) 1995-03-29 2000-07-18 Abgenix, Inc. Production of antibodies using Cre-mediated site-specific recombination
ES2181900T3 (es) 1995-06-07 2003-03-01 Invitrogen Corp Clonacion recombinante in vitro usanto sitios de recombinacion por ingenieria genetica.
US6143557A (en) 1995-06-07 2000-11-07 Life Technologies, Inc. Recombination cloning using engineered recombination sites
US5801030A (en) 1995-09-01 1998-09-01 Genvec, Inc. Methods and vectors for site-specific recombination
EP0927263A1 (en) 1996-01-05 1999-07-07 Genetic Therapy, Inc. Recombinase-mediated generation of adenoviral vectors
JP2001513336A (ja) 1997-08-22 2001-09-04 ロスリン インスティチュート（エディンバラ） トランスジェニック動物の生産における「マリーナ」トランスポザンの使用
US6140129A (en) 1997-09-17 2000-10-31 Wisconsin Alumni Research Foundation Chromosomal targeting in bacteria using FLP recombinase
US5929301A (en) 1997-11-18 1999-07-27 Pioneer Hi-Bred International Nucleic acid sequence encoding FLP recombinase
CA2306188C (en) 1997-11-18 2008-08-05 Pioneer Hi-Bred International, Inc. A novel method for the integration of foreign dna into eukaryotic genomes
ES2308327T3 (es) 1997-11-18 2008-12-01 Pioneer Hi-Bred International, Inc. Composiciones y metodos para modificacion genetica de plantas.
CN1273605C (zh) * 1999-10-19 2006-09-06 米诺斯生物系统有限公司 蛋白质生产系统
GB0218030D0 (en) * 2002-08-02 2002-09-11 Minos Biosystems Multi-submit protein production system
US9357755B2 (en) * 2003-10-28 2016-06-07 The University Of Wyoming Production of human glycosylated proteins in silk worm
US20070067855A1 (en) * 2003-10-28 2007-03-22 Chesapeake Perl, Inc. Production of human glycosylated proteins in transgenic insects
WO2011057825A1 (en) * 2009-11-16 2011-05-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Induction of gene expression in arthropods

Also Published As

Publication number Publication date
BR112022018442A2 (pt) 2022-11-22
IL296417A (en) 2022-11-01
KR20220155584A (ko) 2022-11-23
AU2021237476A1 (en) 2022-09-29
WO2021188445A1 (en) 2021-09-23
US20230172175A1 (en) 2023-06-08
CN115334876A (zh) 2022-11-11
JP2023517779A (ja) 2023-04-26
EP4120829A1 (en) 2023-01-25
CA3171935A1 (en) 2021-09-23

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