MX2022010454A - Uso de analogos de ciclosporina para el tratamiento contra el cancer. - Google Patents

Uso de analogos de ciclosporina para el tratamiento contra el cancer.

Info

Publication number
MX2022010454A
MX2022010454A MX2022010454A MX2022010454A MX2022010454A MX 2022010454 A MX2022010454 A MX 2022010454A MX 2022010454 A MX2022010454 A MX 2022010454A MX 2022010454 A MX2022010454 A MX 2022010454A MX 2022010454 A MX2022010454 A MX 2022010454A
Authority
MX
Mexico
Prior art keywords
treating cancer
cyclosporine
cyclosporine analogues
crv431
stereoisomer
Prior art date
Application number
MX2022010454A
Other languages
English (en)
Inventor
Daren R Ure
Daniel J Trepanier
Patrick R Mayo
Robert T Foster
Original Assignee
Hepion Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hepion Pharmaceuticals Inc filed Critical Hepion Pharmaceuticals Inc
Publication of MX2022010454A publication Critical patent/MX2022010454A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

En la presente se describen métodos, composiciones y kits adecuados para usarse en la prevención y tratamiento contra enfermedades proliferativas tales como el cáncer. Los métodos comprenden que le sea administrable a un sujeto que lo necesite, una composición que comprende un análogo de ciclosporina (por ejemplo, CRV431), o una sal, solvato, estereoisómero farmacéuticamente aceptables del mismo. Las composiciones y kits comprenden un análogo de ciclosporina (por ejemplo, CRV431), o una sal, solvato, estereoisómero farmacéuticamente aceptables del mismo.
MX2022010454A 2020-02-25 2021-02-24 Uso de analogos de ciclosporina para el tratamiento contra el cancer. MX2022010454A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062981383P 2020-02-25 2020-02-25
PCT/US2021/019480 WO2021173723A1 (en) 2020-02-25 2021-02-24 Use of cyclosporine analogues for treating cancer

Publications (1)

Publication Number Publication Date
MX2022010454A true MX2022010454A (es) 2022-09-19

Family

ID=74885085

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022010454A MX2022010454A (es) 2020-02-25 2021-02-24 Uso de analogos de ciclosporina para el tratamiento contra el cancer.

Country Status (13)

Country Link
US (1) US20210269479A1 (es)
EP (1) EP4110346A1 (es)
JP (1) JP2023515569A (es)
KR (1) KR20220145849A (es)
CN (1) CN115484961A (es)
AR (1) AR121404A1 (es)
AU (1) AU2021227230A1 (es)
BR (1) BR112022016960A2 (es)
CA (1) CA3172368A1 (es)
IL (1) IL295498A (es)
MX (1) MX2022010454A (es)
TW (1) TW202140057A (es)
WO (1) WO2021173723A1 (es)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2308149T3 (es) * 2003-02-12 2008-12-01 Biocompatibles Uk Limited Composicion para la quimioemboloterapia de tumores solidos.
AU2011342284C1 (en) * 2010-12-15 2017-07-13 Contravir Pharmaceuticals, Inc. Cyclosporine analogue molecules modified at amino acid 1 and 3
ES2858517T3 (es) * 2014-11-07 2021-09-30 Sublimity Therapeutics Ltd Composiciones que comprenden ciclosporina
CA3024320A1 (en) * 2016-05-17 2017-11-23 S&T Global Inc. Novel cyclosporin derivatives and uses thereof
WO2018106928A1 (en) * 2016-12-08 2018-06-14 Contravir Pharmaceuticals, Inc. Treatment and prevention of hbv diseases by cyclosporine analogue molecules modified at amino acides 1 and 3
US20180296588A1 (en) * 2017-04-14 2018-10-18 Contravir Pharmaceuticals, Inc. Combination therapy for treating viral infections
SI3886813T1 (sl) 2018-11-26 2023-05-31 Hepion Pharmaceuticals, Inc. Farmacevtske formulacije analogov ciklosporina

Also Published As

Publication number Publication date
TW202140057A (zh) 2021-11-01
IL295498A (en) 2022-10-01
AU2021227230A1 (en) 2022-09-08
KR20220145849A (ko) 2022-10-31
WO2021173723A8 (en) 2022-08-25
US20210269479A1 (en) 2021-09-02
AR121404A1 (es) 2022-06-01
BR112022016960A2 (pt) 2022-10-25
JP2023515569A (ja) 2023-04-13
CN115484961A (zh) 2022-12-16
WO2021173723A1 (en) 2021-09-02
EP4110346A1 (en) 2023-01-04
CA3172368A1 (en) 2021-09-02

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