MX2022010193A - Moleculas dirigidas a proteina ras. - Google Patents
Moleculas dirigidas a proteina ras.Info
- Publication number
- MX2022010193A MX2022010193A MX2022010193A MX2022010193A MX2022010193A MX 2022010193 A MX2022010193 A MX 2022010193A MX 2022010193 A MX2022010193 A MX 2022010193A MX 2022010193 A MX2022010193 A MX 2022010193A MX 2022010193 A MX2022010193 A MX 2022010193A
- Authority
- MX
- Mexico
- Prior art keywords
- ras protein
- molecules targeting
- targeting ras
- aspects
- sheet
- Prior art date
Links
- 102000016914 ras Proteins Human genes 0.000 title abstract 2
- 108010014186 ras Proteins Proteins 0.000 title abstract 2
- 230000008685 targeting Effects 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
Abstract
Aspectos de la invención se refieren a moléculas que aparecen de manera no natural configuradas para formar una lámina-beta intermolecular con una proteína RAS humana, así como aplicaciones terapéuticas de las mismas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20158306 | 2020-02-19 | ||
| PCT/EP2021/054125 WO2021165456A1 (en) | 2020-02-19 | 2021-02-19 | Molecules targeting ras protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022010193A true MX2022010193A (es) | 2022-11-14 |
Family
ID=69726430
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022010191A MX2022010191A (es) | 2020-02-19 | 2021-02-19 | Moleculas dirigidas a proteina ras mutante. |
| MX2022010193A MX2022010193A (es) | 2020-02-19 | 2021-02-19 | Moleculas dirigidas a proteina ras. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022010191A MX2022010191A (es) | 2020-02-19 | 2021-02-19 | Moleculas dirigidas a proteina ras mutante. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20230100941A1 (es) |
| EP (2) | EP4106787A1 (es) |
| JP (2) | JP2023516137A (es) |
| KR (2) | KR20220143702A (es) |
| CN (2) | CN115916234A (es) |
| AU (2) | AU2021223702A1 (es) |
| BR (2) | BR112022016517A2 (es) |
| CA (2) | CA3170658A1 (es) |
| IL (2) | IL295634A (es) |
| MX (2) | MX2022010191A (es) |
| WO (2) | WO2021165452A1 (es) |
| ZA (2) | ZA202209632B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230107642A1 (en) | 2020-12-18 | 2023-04-06 | Erasca, Inc. | Tricyclic pyridones and pyrimidones |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| NO309798B1 (no) * | 1999-04-30 | 2001-04-02 | Targovax As | Peptidblanding, samt farmasoytisk sammensetning og kreftvaksine som innbefatter peptidblandingen |
| AU2006326940B2 (en) | 2005-12-22 | 2012-04-19 | Vib Vzw | Means and methods for mediating protein interference |
| US20110318380A1 (en) * | 2008-10-01 | 2011-12-29 | Dako Denmark A/S | MHC Multimers in Cancer Vaccines and Immune Monitoring |
| AU2012228365A1 (en) | 2011-03-11 | 2013-09-19 | Katholieke Universiteit Leuven, K.U.Leuven R&D | Molecules and methods for inhibition and detection of proteins |
| WO2016154047A2 (en) * | 2015-03-20 | 2016-09-29 | Memorial Sloan-Kettering Cancer Center | Monoclonal antigen-binding proteins to intracellular oncogene products |
| US20180282397A1 (en) * | 2016-12-15 | 2018-10-04 | University Of Southern California | Polypeptides that bind activated ras proteins |
| US11771749B2 (en) * | 2017-02-03 | 2023-10-03 | The Medical College Of Wisconsin, Inc. | KRAS peptide vaccine compositions and method of use |
| MA50180A (fr) * | 2017-09-20 | 2021-05-26 | Us Health | Récepteurs de lymphocytes t restreints au hla de classe ii contre kras muté |
-
2021
- 2021-02-19 JP JP2022550695A patent/JP2023516137A/ja active Pending
- 2021-02-19 CN CN202180028937.8A patent/CN115916234A/zh active Pending
- 2021-02-19 US US17/800,738 patent/US20230100941A1/en active Pending
- 2021-02-19 MX MX2022010191A patent/MX2022010191A/es unknown
- 2021-02-19 WO PCT/EP2021/054118 patent/WO2021165452A1/en unknown
- 2021-02-19 EP EP21704699.4A patent/EP4106787A1/en active Pending
- 2021-02-19 IL IL295634A patent/IL295634A/en unknown
- 2021-02-19 CN CN202180028959.4A patent/CN115427057A/zh active Pending
- 2021-02-19 BR BR112022016517A patent/BR112022016517A2/pt not_active Application Discontinuation
- 2021-02-19 MX MX2022010193A patent/MX2022010193A/es unknown
- 2021-02-19 CA CA3170658A patent/CA3170658A1/en active Pending
- 2021-02-19 BR BR112022016513A patent/BR112022016513A2/pt not_active Application Discontinuation
- 2021-02-19 AU AU2021223702A patent/AU2021223702A1/en active Pending
- 2021-02-19 KR KR1020227031655A patent/KR20220143702A/ko unknown
- 2021-02-19 AU AU2021222972A patent/AU2021222972A1/en active Pending
- 2021-02-19 WO PCT/EP2021/054125 patent/WO2021165456A1/en unknown
- 2021-02-19 KR KR1020227031654A patent/KR20220143701A/ko unknown
- 2021-02-19 JP JP2022550678A patent/JP2023514420A/ja active Pending
- 2021-02-19 IL IL295623A patent/IL295623A/en unknown
- 2021-02-19 CA CA3171925A patent/CA3171925A1/en active Pending
- 2021-02-19 EP EP21704697.8A patent/EP4106785A1/en active Pending
- 2021-02-19 US US17/800,818 patent/US20230090247A1/en active Pending
-
2022
- 2022-08-29 ZA ZA2022/09632A patent/ZA202209632B/en unknown
- 2022-08-30 ZA ZA2022/09674A patent/ZA202209674B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL295623A (en) | 2022-10-01 |
| BR112022016513A2 (pt) | 2022-10-11 |
| EP4106787A1 (en) | 2022-12-28 |
| AU2021223702A1 (en) | 2022-08-25 |
| ZA202209674B (en) | 2024-01-31 |
| US20230100941A1 (en) | 2023-03-30 |
| CN115427057A (zh) | 2022-12-02 |
| JP2023514420A (ja) | 2023-04-05 |
| CN115916234A (zh) | 2023-04-04 |
| KR20220143701A (ko) | 2022-10-25 |
| ZA202209632B (en) | 2024-01-31 |
| CA3170658A1 (en) | 2021-08-26 |
| BR112022016517A2 (pt) | 2022-10-11 |
| IL295634A (en) | 2022-10-01 |
| EP4106785A1 (en) | 2022-12-28 |
| WO2021165452A1 (en) | 2021-08-26 |
| MX2022010191A (es) | 2022-11-14 |
| KR20220143702A (ko) | 2022-10-25 |
| AU2021222972A1 (en) | 2022-08-25 |
| US20230090247A1 (en) | 2023-03-23 |
| CA3171925A1 (en) | 2021-08-26 |
| WO2021165456A1 (en) | 2021-08-26 |
| JP2023516137A (ja) | 2023-04-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12019502870A1 (en) | Small molecule modulators of human sting | |
| CY1125025T1 (el) | 2-φορμυλ-3-υδροξυφαινυλοξυμεθυλ ενωσεις ικανες ρυθμισης αιμοσφαιρινης | |
| PH12020500396A1 (en) | Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1) inhibitors and uses thereof | |
| PH12018502429A1 (en) | Antibody molecules for cancer treatment | |
| CY1124896T1 (el) | Αντισωματα κατα της αλφα-συνουκλεïνης και χρησεις αυτων | |
| MX2019009255A (es) | Proteínas quiméricas dirigidas y sus usos. | |
| EA201991997A1 (ru) | Комбинированная терапия | |
| EA202191280A1 (ru) | Конструкции для доставки для трансцитоза и связанные способы | |
| EA201891573A1 (ru) | Конъюгат терапевтических ферментов | |
| EA202191175A1 (ru) | Сконструированные с цистеином конъюгаты антитело-лекарственное средство, содержащие пептидсодержащие линкеры | |
| BR112021019070A2 (pt) | Ligantes de pseudoquinase tyk2 | |
| EA201992516A1 (ru) | Способ получения бифункциональных белков и их производных | |
| ZA202209674B (en) | Molecules targeting ras protein | |
| PH12019501064A1 (en) | Ras PROTIEIN DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | |
| EA201792571A1 (ru) | Терапевтическое применение l-4-хлорокинуренина | |
| EA202092305A1 (ru) | Соединения в качестве модуляторов сигнализации tlr2 | |
| PH12020551331A1 (en) | Treatment and prevention of pre-eclampsia | |
| EA202191758A1 (ru) | Пептиды для лечения и профилактики диабета и связанных с ним заболеваний | |
| EA202192488A1 (ru) | Антитела против tsg-6 и их применения | |
| CR20210499A (es) | Compuestos y composiciones como moduladores de la señalización de tlr | |
| MX2021007271A (es) | Nuevas moleculas de acido nucleico conjugado y sus usos. | |
| ATE536368T1 (de) | Konjugate von zytotoxischen verbindungen mit peptiden | |
| AU2021304762B2 (en) | Novel polypeptide and therapeutic use thereof | |
| WO2020139788A3 (en) | Targeted delivery of therapeutic molecules | |
| MX2022010958A (es) | Moleculas procesadas por la proteasa. |