MX2022009582A - Analisis moleculares usando fragmentos largos extracelulares circulantes en el embarazo. - Google Patents

Analisis moleculares usando fragmentos largos extracelulares circulantes en el embarazo.

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Publication number
MX2022009582A
MX2022009582A MX2022009582A MX2022009582A MX2022009582A MX 2022009582 A MX2022009582 A MX 2022009582A MX 2022009582 A MX2022009582 A MX 2022009582A MX 2022009582 A MX2022009582 A MX 2022009582A MX 2022009582 A MX2022009582 A MX 2022009582A
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Mexico
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dna fragments
free dna
cell
snps
cpg sites
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MX2022009582A
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English (en)
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Peiyong Jiang
Kwan Chee Chan
Wenlei Peng
Yuk- Ming Dennis Lo
Rossa Wai Kwun Chiu
Suk Hang Cheng
Cheuk Yin Yu
Yee Ting Cheung
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Univ Hong Kong Chinese
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Publication of MX2022009582A publication Critical patent/MX2022009582A/es

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Abstract

Los métodos y sistemas descritos en la presente implican el uso de fragmentos largos de ADN extracelular circulante para analizar una muestra biológica de una persona gestante. El estado de los sitios de CpG metilados y los polimorfismos de un solo nucleótido (SNP) se usa a menudo para analizar fragmentos de ADN de una muestra biológica. Un sitio CpG y un SNP suelen estar separados del sitio CpG o SNP más cercano por cientos o miles de pares de bases. Es improbable o imposible encontrar dos o más sitios de CpG o SNP consecutivos en la mayoría de los fragmentos de ADN extracelular circulante. Los fragmentos de ADN extracelular circulante de más de 600 pb pueden incluir múltiples sitios de CpG y/o SNP. La presencia de múltiples sitios de CpG y/o SNP en fragmentos largos de ADN extracelular circulante puede permitir un análisis que solo con fragmentos cortos de ADN extracelular circulante. Los fragmentos largos de ADN extra-celular circulante pueden usarse para identificar un tejido de origen y/o proporcionar información sobre un feto en una mujer embarazada.
MX2022009582A 2020-02-05 2021-02-05 Analisis moleculares usando fragmentos largos extracelulares circulantes en el embarazo. MX2022009582A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062970634P 2020-02-05 2020-02-05
US202163135486P 2021-01-08 2021-01-08
PCT/CN2021/075394 WO2021155831A1 (en) 2020-02-05 2021-02-05 Molecular analyses using long cell-free fragments in pregnancy

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MX2022009820A MX2022009820A (es) 2020-02-05 2022-08-04 Analisis moleculares usando fragmentos largos extracelulares circulantes en el embarazo.

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US (3) US20210265007A1 (es)
EP (1) EP4069864A4 (es)
JP (3) JP7311934B2 (es)
KR (2) KR20230113840A (es)
CN (2) CN115066504A (es)
AU (3) AU2021216616B2 (es)
BR (2) BR112022015073A2 (es)
CA (1) CA3164433A1 (es)
GB (4) GB2605736B (es)
IL (3) IL303888A (es)
MX (2) MX2022009582A (es)
NZ (1) NZ790326A (es)
TW (2) TWI835367B (es)
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WO2024044749A1 (en) * 2022-08-26 2024-02-29 Fred Hutchinson Cancer Center Cell-free dna sequence data analysis techniques for estimating fetal fraction and predicting preeclampsia
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US20210265007A1 (en) 2021-08-26
GB202313363D0 (en) 2023-10-18
GB202305176D0 (en) 2023-05-24
US11591642B2 (en) 2023-02-28
KR102662186B1 (ko) 2024-05-07
KR20230113840A (ko) 2023-08-01
JP2023504939A (ja) 2023-02-07
JP2023123759A (ja) 2023-09-05
US20220275433A1 (en) 2022-09-01
MX2022009820A (es) 2022-09-05
WO2021155831A1 (en) 2021-08-12
CN116004786A (zh) 2023-04-25
US11371084B2 (en) 2022-06-28
IL294431B2 (en) 2023-05-01
GB202405740D0 (en) 2024-06-05
IL298811A (en) 2023-02-01
CA3164433A1 (en) 2021-08-12
IL294431A (en) 2022-09-01
BR112022015073A2 (pt) 2022-11-16
TWI784407B (zh) 2022-11-21
GB202209581D0 (en) 2022-08-10
JP7416501B2 (ja) 2024-01-17
GB2614994A (en) 2023-07-26
GB2605736A (en) 2022-10-12
AU2024201092A1 (en) 2024-03-14
JP2024045112A (ja) 2024-04-02
NZ790326A (en) 2023-07-28
IL303888A (en) 2023-08-01
TWI835367B (zh) 2024-03-11
TW202307216A (zh) 2023-02-16
AU2023204613A1 (en) 2023-08-03
GB2605736B (en) 2023-05-24
EP4069864A1 (en) 2022-10-12
BR122022015680A2 (pt) 2022-12-06
GB2620304A (en) 2024-01-03
IL298811B1 (en) 2023-07-01
AU2021216616A1 (en) 2022-07-21
US20210254142A1 (en) 2021-08-19
AU2021216616B2 (en) 2023-04-20
EP4069864A4 (en) 2023-01-25
IL298811B2 (en) 2023-11-01
AU2023204613B2 (en) 2023-11-23
KR20220118551A (ko) 2022-08-25
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JP7311934B2 (ja) 2023-07-20
CN115066504A (zh) 2022-09-16
GB2620304B (en) 2024-06-19
GB2614994B (en) 2023-10-18
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