MX2022008086A - Preparacion y/o formulacion de proteinas reticuladas con polisacaridos. - Google Patents
Preparacion y/o formulacion de proteinas reticuladas con polisacaridos.Info
- Publication number
- MX2022008086A MX2022008086A MX2022008086A MX2022008086A MX2022008086A MX 2022008086 A MX2022008086 A MX 2022008086A MX 2022008086 A MX2022008086 A MX 2022008086A MX 2022008086 A MX2022008086 A MX 2022008086A MX 2022008086 A MX2022008086 A MX 2022008086A
- Authority
- MX
- Mexico
- Prior art keywords
- cross
- linked
- formulation
- preparation
- protein matrix
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 102000004169 proteins and genes Human genes 0.000 title abstract 6
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 238000009472 formulation Methods 0.000 title abstract 3
- 150000004676 glycans Chemical class 0.000 title abstract 2
- 229920001282 polysaccharide Polymers 0.000 title abstract 2
- 239000005017 polysaccharide Substances 0.000 title abstract 2
- 239000011159 matrix material Substances 0.000 abstract 3
- 102000008186 Collagen Human genes 0.000 abstract 2
- 108010035532 Collagen Proteins 0.000 abstract 2
- 102100033167 Elastin Human genes 0.000 abstract 2
- 108010014258 Elastin Proteins 0.000 abstract 2
- 150000001720 carbohydrates Chemical class 0.000 abstract 2
- 229920001436 collagen Polymers 0.000 abstract 2
- 239000003431 cross linking reagent Substances 0.000 abstract 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- 102000009027 Albumins Human genes 0.000 abstract 1
- 108010088751 Albumins Proteins 0.000 abstract 1
- 108060003951 Immunoglobulin Proteins 0.000 abstract 1
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 229920002678 cellulose Chemical class 0.000 abstract 1
- 239000001913 cellulose Chemical class 0.000 abstract 1
- 238000004132 cross linking Methods 0.000 abstract 1
- 229920002549 elastin Polymers 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 102000018358 immunoglobulin Human genes 0.000 abstract 1
- 229940072221 immunoglobulins Drugs 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
Classifications
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Abstract
Se proporcionan las composiciones y/o formulaciones terapéuticas que contienen: al menos una matriz de proteína reticulada, en donde la al menos una matriz de proteína reticulada contiene al menos un residuo de proteína y al menos un residuo que contiene sacárido, y los métodos para producir estas. La matriz de proteína reticulada puede obtenerse a partir de la reticulación de una proteína de longitud completa o de longitud considerablemente competa, como puede ser tropoelastina, elastina, albúmina, colágena, monómeros de colágena, inmunoglobulinas, insulina y/o derivados o combinaciones de éstas, con un sacárido que contenga un agente reticulador, como puede ser un agente reticulador polisacárido obtenido de, por ejemplo, ácido hialurónico o un derivado de celulosa. Las composiciones terapéuticas se pueden administrar por vía tópica o por inyección. La presente divulgación también proporciona los métodos, sistemas y/o kits para la preparación y/o formulación de las composiciones que se describen en la presente.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34494010P | 2010-11-23 | 2010-11-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022008086A true MX2022008086A (es) | 2022-07-27 |
Family
ID=46145287
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013005746A MX349070B (es) | 2010-11-23 | 2011-11-22 | Preparacion y/o formulacion de proteinas reticuladas con polisacaridos. |
| MX2022008086A MX2022008086A (es) | 2010-11-23 | 2013-05-22 | Preparacion y/o formulacion de proteinas reticuladas con polisacaridos. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013005746A MX349070B (es) | 2010-11-23 | 2011-11-22 | Preparacion y/o formulacion de proteinas reticuladas con polisacaridos. |
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| Country | Link |
|---|---|
| US (5) | US9611312B2 (es) |
| EP (3) | EP3485919B1 (es) |
| JP (6) | JP2013544593A (es) |
| KR (2) | KR101955549B1 (es) |
| CN (2) | CN107281549B (es) |
| AU (4) | AU2011334599B2 (es) |
| BR (1) | BR112013012772B1 (es) |
| CA (1) | CA2818728C (es) |
| DK (1) | DK2643029T3 (es) |
| ES (1) | ES2725207T3 (es) |
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| MX (2) | MX349070B (es) |
| TR (1) | TR201903325T4 (es) |
| WO (1) | WO2012068619A1 (es) |
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| ES2725207T3 (es) * | 2010-11-23 | 2019-09-20 | Allergan Pharmaceuticals Int Ltd | Preparación y/o formulación de proteínas reticuladas con polisacáridos |
| US20130116411A1 (en) * | 2011-09-06 | 2013-05-09 | Allergan, Inc. | Methods of making hyaluronic acid/collagen compositions |
| WO2013044314A1 (en) * | 2011-09-30 | 2013-04-04 | The University Of Sydney | In vivo synthesis of elastic fiber |
| KR101279812B1 (ko) * | 2012-05-16 | 2013-06-28 | 세원셀론텍(주) | 연골조직 수복용 조성물의 제조방법 |
| WO2014063194A1 (en) | 2012-10-23 | 2014-05-01 | The University Of Sydney | Elastic hydrogel |
| CN105246520B (zh) | 2012-12-10 | 2017-11-21 | 埃拉斯塔根私人有限公司 | 可缩放的三维弹性构建体制造 |
| MX377200B (es) | 2013-08-13 | 2025-03-07 | Allergan Pharmaceuticals Int Ltd | Regeneracion de tejido dañado. |
| CN103550826B (zh) | 2013-10-31 | 2015-07-08 | 广州优得清生物科技有限公司 | 异种角膜材料的制备方法 |
| KR20150053606A (ko) * | 2013-11-08 | 2015-05-18 | 세원셀론텍(주) | 콜라겐과 히알루론산의 천연가교를 통한 고무성질의 물성이 강화된 생체재료물질 및 그 제조방법 |
| AU2015353653A1 (en) * | 2014-11-26 | 2017-06-15 | Integra Lifesciences Corporation | Process for preparing tissue regeneration matrix |
| HK1257488A1 (zh) * | 2015-09-01 | 2019-10-25 | Allergan Pharmaceuticals International Limited | 骨形成 |
| CA3031097A1 (en) * | 2016-07-18 | 2018-01-25 | Tissuegen, Inc. | Methods and compositions for maintaining the conformation and structural integrity of biomolecules |
| US10143764B2 (en) * | 2016-08-01 | 2018-12-04 | The Procter & Gamble Company | Phase-stable, sprayable freshening compositions comprising suspended particles |
| DE102016216182A1 (de) * | 2016-08-29 | 2018-03-01 | Tetec Tissue Engineering Technologies Ag | Kombination, insbesondere zum Behandeln eines Knorpeldefekts |
| JP2019218265A (ja) * | 2016-09-14 | 2019-12-26 | 生化学工業株式会社 | ペプチドの血中滞留性を増強させる方法 |
| CN107185028A (zh) * | 2017-05-05 | 2017-09-22 | 惠州华阳医疗器械有限公司 | 一种止血防粘连材料及其制备方法与应用 |
| CN109900814B (zh) * | 2017-12-08 | 2021-06-08 | 中国科学院大连化学物理研究所 | 基于糖苷键质谱可碎裂型化学交联剂的分析方法及应用 |
| LU101045B1 (en) | 2018-12-11 | 2020-06-11 | Qventis GmbH | Method for the manufacture and use of a bionic hydrogel composition for medical applications |
| EP3797800A1 (en) * | 2019-05-02 | 2021-03-31 | Institut National De La Sante Et De La Recherche Medicale - Inserm | Hyaluronic acid hydrogels with prolonged antimicrobial activity |
| CA3136074A1 (en) * | 2019-05-03 | 2020-11-12 | Robert Daniels | Scar prevention and/or treatment |
| JP2023525155A (ja) * | 2020-05-14 | 2023-06-14 | アラーガン ファーマシューティカルズ インターナショナル リミテッド | ヒアルロン酸に架橋したトロポエラスチンを含む組成物及びその使用方法 |
| WO2023092208A1 (pt) * | 2021-11-25 | 2023-06-01 | Universidade Estadual De Campinas | Processo de obtenção de solução polimérica injetável fotoreticulável, solução polimérica injetável fotoreticulável e seus usos |
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| FR2733426B1 (fr) * | 1995-04-25 | 1997-07-18 | Debacker Yves | Dispositif medical pour le comblement des deformations du volume de la peau telles que rides et cicatrices par injection de 2 formes physico-chimiques differentes d'un polymere biologique |
| US5866165A (en) | 1997-01-15 | 1999-02-02 | Orquest, Inc. | Collagen-polysaccharide matrix for bone and cartilage repair |
| AU756864B2 (en) | 1998-02-17 | 2003-01-23 | Takara Bio Inc. | Sulfated saccharides |
| JP3762234B2 (ja) | 1998-02-17 | 2006-04-05 | タカラバイオ株式会社 | ポリ陽イオン物質で架橋された硫酸化多糖ならびにその製造方法 |
| JP2002518135A (ja) | 1998-06-23 | 2002-06-25 | サージカル シーランツ, インコーポレイテッド | 生体接着性の外科用シーラントおよび移植可能デバイスのためのカルボジイミド架橋アルブミン |
| US6682760B2 (en) * | 2000-04-18 | 2004-01-27 | Colbar R&D Ltd. | Cross-linked collagen matrices and methods for their preparation |
| TW574302B (en) * | 2001-08-10 | 2004-02-01 | Ind Tech Res Inst | A method for producing cross-linked hyaluronic acid-protein bio-composites |
| DE10209821A1 (de) * | 2002-03-06 | 2003-09-25 | Biotechnologie Ges Mittelhesse | Kopplung von Proteinen an ein modifiziertes Polysaccharid |
| AU2004297231B2 (en) * | 2003-12-04 | 2012-02-02 | University Of Utah Research Foundation | Modified macromolecules and associated methods of synthesis and use |
| CN1294994C (zh) * | 2004-07-05 | 2007-01-17 | 暨南大学 | 可注射型胶原基软组织填充材料及其制备方法 |
| AU2006286158A1 (en) * | 2005-09-02 | 2007-03-08 | Colbar Lifescience Ltd. | Cross-linked polysaccharide and protein matrices and methods for their preparation |
| CN101522228A (zh) * | 2006-08-02 | 2009-09-02 | 克赫里昂恩克斯公司 | 尤其可用于组织填补和瘢痕形成的可植入制剂 |
| ITMI20061726A1 (it) * | 2006-09-11 | 2008-03-12 | Fidia Farmaceutici | Derivati crosslinkati a base di acido ialuronico reticolato via click chemistry |
| US7700126B2 (en) * | 2006-09-29 | 2010-04-20 | Martin Kean Chong Ng | Tropoelastin-based protoelastin biomaterials |
| CA2669114C (en) * | 2006-11-13 | 2014-12-16 | The University Of Sydney | Use of tropoelastin for repair or restoration of tissue |
| WO2008067655A1 (en) * | 2006-12-05 | 2008-06-12 | Q6 Biomaterials Inc. | Biocompatible hydrogel-based scaffolds |
| CN101200504B (zh) * | 2006-12-11 | 2010-05-12 | 上海百瑞吉生物医药有限公司 | 高分子巯基化改性衍生物及其交联材料 |
| US20090068250A1 (en) | 2007-09-07 | 2009-03-12 | Philippe Gravagna | Bioresorbable and biocompatible compounds for surgical use |
| US8697044B2 (en) * | 2007-10-09 | 2014-04-15 | Allergan, Inc. | Crossed-linked hyaluronic acid and collagen and uses thereof |
| CN101244290A (zh) * | 2007-11-30 | 2008-08-20 | 顾其胜 | 一种用于组织填充的交联透明质酸微粒凝胶的制备方法 |
| CA2706701C (en) | 2007-12-03 | 2016-10-25 | Tenaxis Medical, Inc. | Biocompatible phase invertible proteinaceous compositions |
| WO2010053918A1 (en) * | 2008-11-05 | 2010-05-14 | Hancock Jaffe Laboratories, Inc. | Composite containing collagen and elastin as a dermal expander and tissue filler |
| ES2725207T3 (es) * | 2010-11-23 | 2019-09-20 | Allergan Pharmaceuticals Int Ltd | Preparación y/o formulación de proteínas reticuladas con polisacáridos |
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