MX2022005670A - Composiciones y metodos para recombinacion de alta eficiencia de moleculas de arn. - Google Patents
Composiciones y metodos para recombinacion de alta eficiencia de moleculas de arn.Info
- Publication number
- MX2022005670A MX2022005670A MX2022005670A MX2022005670A MX2022005670A MX 2022005670 A MX2022005670 A MX 2022005670A MX 2022005670 A MX2022005670 A MX 2022005670A MX 2022005670 A MX2022005670 A MX 2022005670A MX 2022005670 A MX2022005670 A MX 2022005670A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- compositions
- rna molecules
- molecules
- reconstitution
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
- C12N2840/445—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor for trans-splicing, e.g. polypyrimidine tract, branch point splicing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962933714P | 2019-11-11 | 2019-11-11 | |
| PCT/US2020/025430 WO2020205604A1 (en) | 2019-03-29 | 2020-03-27 | High-efficiency reconstitution of rna molecules |
| PCT/US2020/053643 WO2021096605A1 (en) | 2019-11-11 | 2020-09-30 | Compositions and methods for high-efficiency recombination of rna molecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022005670A true MX2022005670A (es) | 2022-07-19 |
Family
ID=75911442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022005670A MX2022005670A (es) | 2019-11-11 | 2020-09-30 | Composiciones y metodos para recombinacion de alta eficiencia de moleculas de arn. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220265855A1 (https=) |
| EP (1) | EP4058571A1 (https=) |
| JP (2) | JP7759106B2 (https=) |
| KR (1) | KR20220113940A (https=) |
| CN (1) | CN114945666A (https=) |
| AU (1) | AU2020384996A1 (https=) |
| BR (1) | BR112022009006A2 (https=) |
| CA (1) | CA3157799A1 (https=) |
| IL (1) | IL292904A (https=) |
| MX (1) | MX2022005670A (https=) |
| WO (1) | WO2021096605A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020205604A1 (en) | 2019-03-29 | 2020-10-08 | Salk Institute For Biological Studies | High-efficiency reconstitution of rna molecules |
| KR20220157944A (ko) | 2020-02-21 | 2022-11-29 | 아카우오스, 인크. | 인간 대상체에서 비-연령-연관 청각 장애를 치료하기 위한 조성물 및 방법 |
| AU2022337146A1 (en) * | 2021-09-03 | 2024-03-14 | Tacit Therapeutics, Inc. | Rna editing via recruitment of spliceosome components |
| CA3240197A1 (en) * | 2021-12-10 | 2025-02-26 | Aavantibio, Inc. | Compositions comprising kozak sequences selected for enhanced expression |
| WO2023250324A2 (en) * | 2022-06-21 | 2023-12-28 | The Regents Of The University Of California | Compositions and methods for reducing rna levels |
| US20260055400A1 (en) * | 2022-06-21 | 2026-02-26 | The Regents Of The University Of California | Compositions and methods for treating huntington's disease |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6110743A (en) | 1995-02-10 | 2000-08-29 | The Regents Of The University Of California | Development and use of human pancreatic cell lines |
| US20060134658A1 (en) * | 2004-08-09 | 2006-06-22 | Garcia-Blanco Mariano A | Use of RNA trans-splicing for generation of interfering RNA molecules |
| ES2763526T3 (es) * | 2014-07-03 | 2020-05-29 | Hoffmann La Roche | Sistemas de expresión de polipéptidos |
-
2020
- 2020-09-30 IL IL292904A patent/IL292904A/en unknown
- 2020-09-30 CA CA3157799A patent/CA3157799A1/en active Pending
- 2020-09-30 EP EP20793875.4A patent/EP4058571A1/en active Pending
- 2020-09-30 BR BR112022009006A patent/BR112022009006A2/pt unknown
- 2020-09-30 CN CN202080092659.8A patent/CN114945666A/zh active Pending
- 2020-09-30 MX MX2022005670A patent/MX2022005670A/es unknown
- 2020-09-30 KR KR1020227019191A patent/KR20220113940A/ko active Pending
- 2020-09-30 AU AU2020384996A patent/AU2020384996A1/en active Pending
- 2020-09-30 JP JP2022526727A patent/JP7759106B2/ja active Active
- 2020-09-30 WO PCT/US2020/053643 patent/WO2021096605A1/en not_active Ceased
-
2022
- 2022-05-10 US US17/741,311 patent/US20220265855A1/en active Pending
-
2025
- 2025-05-12 JP JP2025079571A patent/JP2025118824A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2025118824A (ja) | 2025-08-13 |
| JP2023500957A (ja) | 2023-01-11 |
| CN114945666A (zh) | 2022-08-26 |
| WO2021096605A1 (en) | 2021-05-20 |
| US20220265855A1 (en) | 2022-08-25 |
| IL292904A (en) | 2022-07-01 |
| EP4058571A1 (en) | 2022-09-21 |
| KR20220113940A (ko) | 2022-08-17 |
| JP7759106B2 (ja) | 2025-10-23 |
| AU2020384996A1 (en) | 2022-06-23 |
| BR112022009006A2 (pt) | 2022-10-11 |
| CA3157799A1 (en) | 2021-05-20 |
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