MX2022001802A - Metodos para incrementar la biodisponibilidad de medicamentos farmaceuticos y de venta libre. - Google Patents

Metodos para incrementar la biodisponibilidad de medicamentos farmaceuticos y de venta libre.

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Publication number
MX2022001802A
MX2022001802A MX2022001802A MX2022001802A MX2022001802A MX 2022001802 A MX2022001802 A MX 2022001802A MX 2022001802 A MX2022001802 A MX 2022001802A MX 2022001802 A MX2022001802 A MX 2022001802A MX 2022001802 A MX2022001802 A MX 2022001802A
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MX
Mexico
Prior art keywords
methods
bioavailability
otc
increasing
pharmaceutical drugs
Prior art date
Application number
MX2022001802A
Other languages
English (en)
Inventor
Sean Farmer
Ken Alibek
Original Assignee
Locus Ip Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Locus Ip Co Llc filed Critical Locus Ip Co Llc
Publication of MX2022001802A publication Critical patent/MX2022001802A/es

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    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
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    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
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Abstract

La presente invención se refiere a composiciones y métodos para mejorar la eficacia de compuestos de medicamentos. La presente invención utiliza una composición adyuvante que comprende uno o más bioagentes tensioactivos producidos por microbios y/o isoformas de los mismos para mejorar la biodisponibilidad, estabilidad y ubicación de los medicamentos en un sujeto, para reducir la dosis total que se requiere y para prolongar la estabilidad de pre-administración de los medicamentos.
MX2022001802A 2019-08-10 2020-08-10 Metodos para incrementar la biodisponibilidad de medicamentos farmaceuticos y de venta libre. MX2022001802A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962885233P 2019-08-10 2019-08-10
PCT/US2020/045587 WO2021030250A1 (en) 2019-08-10 2020-08-10 Methods for increasing the bioavailability of otc and pharmaceutical drugs

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MX2022001802A true MX2022001802A (es) 2022-03-11

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