MX2021014761A - Ester isopropilico de acido [((1r,2s,5r)-2-isopropil-5-metil-ciclo hexanocarbonil)-amino]-acetico para el tratamiento de la tos cronica. - Google Patents
Ester isopropilico de acido [((1r,2s,5r)-2-isopropil-5-metil-ciclo hexanocarbonil)-amino]-acetico para el tratamiento de la tos cronica.Info
- Publication number
- MX2021014761A MX2021014761A MX2021014761A MX2021014761A MX2021014761A MX 2021014761 A MX2021014761 A MX 2021014761A MX 2021014761 A MX2021014761 A MX 2021014761A MX 2021014761 A MX2021014761 A MX 2021014761A MX 2021014761 A MX2021014761 A MX 2021014761A
- Authority
- MX
- Mexico
- Prior art keywords
- chronic cough
- treatment
- cyclohexanecarbonyl
- amino
- methyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se relaciona, en general, con el campo de la terapia. Más específicamente, la presente invención se relaciona con un determinado compuesto, éster isopropílico de ácido [((1R,2S,5R)-2-isopropil-5-metil-ciclohexanocarbonil)-amino] -acético (al que también se hace referencia en la presente como ¿AX-8¿ o ¿Gly-O-iPr¿), como se describe en la presente, para usarse en un método de tratamiento del cuerpo humano o animal mediante terapia, más específicamente, para usar en un método de tratamiento de la tos crónica (CC), inclusive, por ejemplo, tos crónica refractaria (RCC) y tos crónica idiopática (ICC), como se describe en la presente.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1908219.7A GB201908219D0 (en) | 2019-06-10 | 2019-06-10 | Therapeutic use of a compound |
| PCT/EP2020/066065 WO2020249607A1 (en) | 2019-06-10 | 2020-06-10 | [((1r,2s,5r)-2-isopropyl-5-methyl-cyclohexanecarbonyl)-amino]-acetic acid isopropyl ester for treatment of chronic cough |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021014761A true MX2021014761A (es) | 2022-02-21 |
Family
ID=67386245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021014761A MX2021014761A (es) | 2019-06-10 | 2020-06-10 | Ester isopropilico de acido [((1r,2s,5r)-2-isopropil-5-metil-ciclo hexanocarbonil)-amino]-acetico para el tratamiento de la tos cronica. |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US20220265594A1 (es) |
| EP (2) | EP4342533A3 (es) |
| JP (1) | JP7181426B2 (es) |
| KR (1) | KR20220019715A (es) |
| CN (1) | CN114007601A (es) |
| AU (1) | AU2020293622A1 (es) |
| BR (1) | BR112021024927A2 (es) |
| CA (1) | CA3143094C (es) |
| CL (1) | CL2021003301A1 (es) |
| DK (1) | DK3980003T3 (es) |
| EA (1) | EA202193006A1 (es) |
| ES (1) | ES2973546T3 (es) |
| FI (1) | FI3980003T3 (es) |
| GB (1) | GB201908219D0 (es) |
| HR (1) | HRP20240312T1 (es) |
| IL (1) | IL288874A (es) |
| JO (1) | JOP20210315A1 (es) |
| LT (1) | LT3980003T (es) |
| MA (1) | MA56105B1 (es) |
| MD (1) | MD3980003T2 (es) |
| MX (1) | MX2021014761A (es) |
| PL (1) | PL3980003T3 (es) |
| PT (1) | PT3980003T (es) |
| RS (1) | RS65224B1 (es) |
| SI (1) | SI3980003T1 (es) |
| WO (1) | WO2020249607A1 (es) |
| ZA (1) | ZA202109580B (es) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7189760B2 (en) * | 2004-04-02 | 2007-03-13 | Millennium Specialty Chemicals | Physiological cooling compositions containing highly purified ethyl ester of N-[[5-methyl-2-(1-methylethyl) cyclohexyl] carbonyl]glycine |
| DK1871738T3 (da) * | 2005-03-29 | 2009-09-21 | Edward T Wei | N-alkylcarbonylaminosyreester- og N-alkylcarbonylaminolactonforbindelser og deres anvendelse |
| CA2819466C (en) * | 2010-12-06 | 2019-11-26 | Edward Tak Wei | [((1r,2s,5r)-2-isopropyl-5-methyl-cyclohexanecarbonyl)-amino]-acetic acid isopropyl ester and related compounds and their use in therapy |
| US8426463B2 (en) * | 2011-04-04 | 2013-04-23 | Edward T. Wei | [((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexanecarbonyl)-amino]-acetic acid isopropyl ester and related compounds and their use in therapy |
| WO2015059433A1 (en) * | 2013-10-22 | 2015-04-30 | Edward Tak Wei | 1-di(sec-butyl)-phosphinoyl-pentane (dapa-2-5) as a topical agent for the treatment of discomfort from non-keratinized stratified epithelial (nkse) tissue |
-
2019
- 2019-06-10 GB GBGB1908219.7A patent/GB201908219D0/en not_active Ceased
-
2020
- 2020-06-10 FI FIEP20732556.4T patent/FI3980003T3/fi active
- 2020-06-10 BR BR112021024927A patent/BR112021024927A2/pt unknown
- 2020-06-10 AU AU2020293622A patent/AU2020293622A1/en active Pending
- 2020-06-10 EP EP23214305.7A patent/EP4342533A3/en active Pending
- 2020-06-10 CN CN202080045857.9A patent/CN114007601A/zh active Pending
- 2020-06-10 US US17/618,394 patent/US20220265594A1/en active Pending
- 2020-06-10 HR HRP20240312TT patent/HRP20240312T1/hr unknown
- 2020-06-10 DK DK20732556.4T patent/DK3980003T3/da active
- 2020-06-10 WO PCT/EP2020/066065 patent/WO2020249607A1/en active Application Filing
- 2020-06-10 SI SI202030384T patent/SI3980003T1/sl unknown
- 2020-06-10 ES ES20732556T patent/ES2973546T3/es active Active
- 2020-06-10 PL PL20732556.4T patent/PL3980003T3/pl unknown
- 2020-06-10 EP EP20732556.4A patent/EP3980003B1/en active Active
- 2020-06-10 CA CA3143094A patent/CA3143094C/en active Active
- 2020-06-10 LT LTEPPCT/EP2020/066065T patent/LT3980003T/lt unknown
- 2020-06-10 JP JP2021571758A patent/JP7181426B2/ja active Active
- 2020-06-10 MA MA56105A patent/MA56105B1/fr unknown
- 2020-06-10 EA EA202193006A patent/EA202193006A1/ru unknown
- 2020-06-10 JO JOP/2021/0315A patent/JOP20210315A1/ar unknown
- 2020-06-10 MD MDE20220407T patent/MD3980003T2/ro unknown
- 2020-06-10 KR KR1020217042443A patent/KR20220019715A/ko unknown
- 2020-06-10 PT PT207325564T patent/PT3980003T/pt unknown
- 2020-06-10 MX MX2021014761A patent/MX2021014761A/es unknown
- 2020-06-10 RS RS20240225A patent/RS65224B1/sr unknown
-
2021
- 2021-11-25 ZA ZA2021/09580A patent/ZA202109580B/en unknown
- 2021-12-09 IL IL288874A patent/IL288874A/en unknown
- 2021-12-10 CL CL2021003301A patent/CL2021003301A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB201908219D0 (en) | 2019-07-24 |
| CA3143094C (en) | 2023-11-07 |
| EA202193006A1 (ru) | 2022-03-17 |
| EP4342533A3 (en) | 2024-05-29 |
| CN114007601A (zh) | 2022-02-01 |
| EP3980003A1 (en) | 2022-04-13 |
| LT3980003T (lt) | 2024-03-12 |
| MA56105B1 (fr) | 2024-03-29 |
| MD3980003T2 (ro) | 2024-05-31 |
| MA56105A (fr) | 2022-04-13 |
| IL288874A (en) | 2022-02-01 |
| JOP20210315A1 (ar) | 2023-01-30 |
| BR112021024927A2 (pt) | 2022-01-18 |
| ZA202109580B (en) | 2023-04-26 |
| CA3143094A1 (en) | 2020-12-17 |
| PL3980003T3 (pl) | 2024-05-20 |
| AU2020293622A1 (en) | 2022-02-03 |
| WO2020249607A1 (en) | 2020-12-17 |
| JP7181426B2 (ja) | 2022-11-30 |
| DK3980003T3 (da) | 2024-02-19 |
| SI3980003T1 (sl) | 2024-05-31 |
| RS65224B1 (sr) | 2024-03-29 |
| CL2021003301A1 (es) | 2022-08-19 |
| HRP20240312T1 (hr) | 2024-05-10 |
| ES2973546T3 (es) | 2024-06-20 |
| KR20220019715A (ko) | 2022-02-17 |
| JP2022534321A (ja) | 2022-07-28 |
| US20220265594A1 (en) | 2022-08-25 |
| EP3980003B1 (en) | 2023-12-13 |
| FI3980003T3 (fi) | 2024-03-01 |
| EP4342533A2 (en) | 2024-03-27 |
| PT3980003T (pt) | 2024-03-05 |
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