MX2021013525A - Metodos y composiciones que usan celulas regulables auxotroficas. - Google Patents

Metodos y composiciones que usan celulas regulables auxotroficas.

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Publication number
MX2021013525A
MX2021013525A MX2021013525A MX2021013525A MX2021013525A MX 2021013525 A MX2021013525 A MX 2021013525A MX 2021013525 A MX2021013525 A MX 2021013525A MX 2021013525 A MX2021013525 A MX 2021013525A MX 2021013525 A MX2021013525 A MX 2021013525A
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MX
Mexico
Prior art keywords
auxotrophic
methods
compositions
cells
regulatable
Prior art date
Application number
MX2021013525A
Other languages
English (en)
Inventor
James Patterson
Matthew Porteus
Volker Wiebking
Original Assignee
Auxolytic Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Auxolytic Ltd filed Critical Auxolytic Ltd
Publication of MX2021013525A publication Critical patent/MX2021013525A/es

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    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41881,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
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Abstract

La presente descripción proporciona composiciones y métodos para producir y usar células hospedadoras auxotróficas modificadas para terapia mejorada que implica la administración de un factor auxotrófico.
MX2021013525A 2019-05-10 2020-05-08 Metodos y composiciones que usan celulas regulables auxotroficas. MX2021013525A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962846073P 2019-05-10 2019-05-10
PCT/US2020/032123 WO2020231819A1 (en) 2019-05-10 2020-05-08 Methods and compositions using auxotrophic regulatable cells

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Publication Number Publication Date
MX2021013525A true MX2021013525A (es) 2022-01-24

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Application Number Title Priority Date Filing Date
MX2021013525A MX2021013525A (es) 2019-05-10 2020-05-08 Metodos y composiciones que usan celulas regulables auxotroficas.

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US (1) US20220290103A1 (es)
EP (1) EP3966329A1 (es)
JP (1) JP2022531930A (es)
KR (1) KR20220017927A (es)
CN (1) CN114072502A (es)
AU (1) AU2020276501A1 (es)
BR (1) BR112021021926A2 (es)
CA (1) CA3138341A1 (es)
IL (1) IL287970A (es)
MX (1) MX2021013525A (es)
SG (1) SG11202111963WA (es)
WO (1) WO2020231819A1 (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190010506A1 (en) * 2016-01-11 2019-01-10 Synlogic, Inc. Bacteria engineered to treat metabolic diseases
GB201618414D0 (en) * 2016-11-01 2016-12-14 Patterson James Regulated cell lines and methods of use thereof

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EP3966329A1 (en) 2022-03-16
KR20220017927A (ko) 2022-02-14
SG11202111963WA (en) 2021-11-29
WO2020231819A1 (en) 2020-11-19
IL287970A (en) 2022-01-01
AU2020276501A1 (en) 2021-12-16
BR112021021926A2 (pt) 2022-03-22
CN114072502A (zh) 2022-02-18
US20220290103A1 (en) 2022-09-15
CA3138341A1 (en) 2020-11-19
JP2022531930A (ja) 2022-07-12

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