MX2021013338A - Método para tratar la tos usando un compuesto de diaminopirimidina. - Google Patents

Método para tratar la tos usando un compuesto de diaminopirimidina.

Info

Publication number
MX2021013338A
MX2021013338A MX2021013338A MX2021013338A MX2021013338A MX 2021013338 A MX2021013338 A MX 2021013338A MX 2021013338 A MX2021013338 A MX 2021013338A MX 2021013338 A MX2021013338 A MX 2021013338A MX 2021013338 A MX2021013338 A MX 2021013338A
Authority
MX
Mexico
Prior art keywords
diaminopyrimidine compound
treating cough
cough
compound
treating
Prior art date
Application number
MX2021013338A
Other languages
English (en)
Spanish (es)
Inventor
Jin Wang
Zhou Lan
Yanping Zhao
Hongjun Wang
Huai Huang
Liying Zhou
Yanan Liu
Yuanyuan Jiang
Huining Liang
Ran An
Original Assignee
Beijing Tide Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Tide Pharmaceutical Co Ltd filed Critical Beijing Tide Pharmaceutical Co Ltd
Publication of MX2021013338A publication Critical patent/MX2021013338A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX2021013338A 2019-04-30 2020-04-29 Método para tratar la tos usando un compuesto de diaminopirimidina. MX2021013338A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2019085180 2019-04-30
PCT/CN2020/087686 WO2020221274A1 (zh) 2019-04-30 2020-04-29 二氨基嘧啶类化合物治疗咳嗽的方法

Publications (1)

Publication Number Publication Date
MX2021013338A true MX2021013338A (es) 2022-01-24

Family

ID=73029672

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021013338A MX2021013338A (es) 2019-04-30 2020-04-29 Método para tratar la tos usando un compuesto de diaminopirimidina.

Country Status (11)

Country Link
US (1) US20220211703A1 (enExample)
EP (1) EP3960179B1 (enExample)
JP (1) JP7665529B2 (enExample)
KR (1) KR102935436B1 (enExample)
CN (1) CN114007619B (enExample)
AU (1) AU2020265327B2 (enExample)
BR (1) BR112021021600A2 (enExample)
MX (1) MX2021013338A (enExample)
SG (1) SG11202111877TA (enExample)
TW (1) TWI736243B (enExample)
WO (1) WO2020221274A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117186068A (zh) * 2017-11-01 2023-12-08 北京泰德制药股份有限公司 P2x3和/或p2x2/3受体拮抗剂、包含其的药物组合物及其用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2557372C (en) * 2004-03-05 2013-01-08 F. Hoffmann-La Roche Ag Diaminopyrimidines as p2x3 and p2x2/3 antagonists
EP1924564B1 (en) * 2005-09-01 2016-11-09 F.Hoffmann-La Roche Ag Diaminopyrimidines as p2x3 and p2x2/3 modulators
AU2007304280B2 (en) 2006-10-04 2013-01-31 F. Hoffmann-La Roche Ag Process for synthesis of phenoxy diaminopyrimidine derivatives
AU2014308606B2 (en) * 2013-08-23 2017-08-03 Afferent Pharmaceuticals Inc. Diaminopyrimidine P2X3 and P2X 2/3 receptor modulators for treatment of acute, sub-acute or chronic cough
DK3355889T3 (da) * 2015-09-29 2023-05-15 Afferent Pharmaceuticals Inc Diaminopyrimidin-p2x3- og p2x2/3-receptormodulatorer til anvendelse i behandling af hoste
WO2017160569A1 (en) * 2016-03-14 2017-09-21 Afferent Pharmaceuticals Inc. Pyrimidines and variants thereof, and uses therefor
AU2017237929B2 (en) * 2016-03-25 2021-04-15 Afferent Pharmaceuticals Inc. Pyrimidines and variants thereof, and uses therefor
CN117186068A (zh) * 2017-11-01 2023-12-08 北京泰德制药股份有限公司 P2x3和/或p2x2/3受体拮抗剂、包含其的药物组合物及其用途

Also Published As

Publication number Publication date
EP3960179B1 (en) 2026-03-18
WO2020221274A1 (zh) 2020-11-05
CN114007619A (zh) 2022-02-01
SG11202111877TA (en) 2021-11-29
BR112021021600A2 (pt) 2022-01-04
CA3138780A1 (en) 2020-11-05
US20220211703A1 (en) 2022-07-07
TWI736243B (zh) 2021-08-11
CN114007619B (zh) 2024-08-06
JP7665529B2 (ja) 2025-04-21
AU2020265327A1 (en) 2021-12-16
JP2022530890A (ja) 2022-07-04
EP3960179A4 (en) 2023-01-25
EP3960179A1 (en) 2022-03-02
KR102935436B1 (ko) 2026-03-05
KR20220007620A (ko) 2022-01-18
AU2020265327B2 (en) 2025-09-11
TW202106302A (zh) 2021-02-16

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