MX2021005686A - Combinacion farmaceutica de anti-ceacam6 y anticuerpos anti-pd-1 o anti-pd-l1 para el tratamiento del cancer. - Google Patents
Combinacion farmaceutica de anti-ceacam6 y anticuerpos anti-pd-1 o anti-pd-l1 para el tratamiento del cancer.Info
- Publication number
- MX2021005686A MX2021005686A MX2021005686A MX2021005686A MX2021005686A MX 2021005686 A MX2021005686 A MX 2021005686A MX 2021005686 A MX2021005686 A MX 2021005686A MX 2021005686 A MX2021005686 A MX 2021005686A MX 2021005686 A MX2021005686 A MX 2021005686A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- treatment
- ceacam6
- pharmaceutical combination
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Abstract
La presente invención se refiere a combinaciones de al menos dos componentes, el componente A y el componente B, siendo el componente A un anticuerpo anti-CEACAM6 y siendo el componente B un anticuerpo anti-PD-1, con preferencia, nivolumab o pembrolizumab, o un anticuerpo anti-PD-L1, con preferencia, atezolizumab, avelumab o durvalumab.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18206206 | 2018-11-14 | ||
PCT/EP2019/080520 WO2020099230A1 (en) | 2018-11-14 | 2019-11-07 | Pharmaceutical combination of anti-ceacam6 and either anti-pd-1 or anti-pd-l1 antibodies for the treatment of cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021005686A true MX2021005686A (es) | 2021-07-07 |
Family
ID=64572076
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021005686A MX2021005686A (es) | 2018-11-14 | 2019-11-07 | Combinacion farmaceutica de anti-ceacam6 y anticuerpos anti-pd-1 o anti-pd-l1 para el tratamiento del cancer. |
Country Status (12)
Country | Link |
---|---|
US (1) | US20220010017A1 (es) |
EP (1) | EP3880705A1 (es) |
JP (1) | JP2022513036A (es) |
KR (1) | KR20210091152A (es) |
CN (1) | CN112996814A (es) |
AU (1) | AU2019379261A1 (es) |
BR (1) | BR112021007448A2 (es) |
CA (1) | CA3119563A1 (es) |
IL (1) | IL283064A (es) |
MX (1) | MX2021005686A (es) |
SG (1) | SG11202105078XA (es) |
WO (1) | WO2020099230A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112021007968A2 (pt) * | 2018-12-19 | 2021-09-08 | Bayer Aktiengesellschaft | Combinação farmacêutica de anticorpos anti-ceacam6 e tim3 |
AU2022340907A1 (en) | 2021-09-02 | 2024-03-07 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Anti-cecam6 antibodies with reduced side-effects |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US4510245A (en) | 1982-11-18 | 1985-04-09 | Chiron Corporation | Adenovirus promoter system |
US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
US4968615A (en) | 1985-12-18 | 1990-11-06 | Ciba-Geigy Corporation | Deoxyribonucleic acid segment from a virus |
PL2439273T3 (pl) | 2005-05-09 | 2019-08-30 | Ono Pharmaceutical Co., Ltd. | Ludzkie przeciwciała monoklonalne przeciwko białku programowanej śmierci komórki 1(pd-1) oraz metody leczenia nowotworów z wykorzystaniem przeciwciał anty-pd-1 samodzielnie lub w połączeniu z innymi immunoterapeutykami |
RS54271B1 (en) | 2005-07-01 | 2016-02-29 | E. R. Squibb & Sons, L.L.C. | HUMAN MONOCLONIC ANTIBODIES FOR LIGAND PROGRAMMED DEATH 1 (PD-L1) |
DOP2006000277A (es) | 2005-12-12 | 2007-08-31 | Bayer Pharmaceuticals Corp | Anticuerpos anti mn y métodos para su utilización |
EP2170959B1 (en) | 2007-06-18 | 2013-10-02 | Merck Sharp & Dohme B.V. | Antibodies to human programmed death receptor pd-1 |
MX2011002252A (es) | 2008-08-25 | 2011-06-24 | Amplimmune Inc | Composiciones de antagonistas del pd-1 y metodos de uso. |
CN114835812A (zh) | 2008-12-09 | 2022-08-02 | 霍夫曼-拉罗奇有限公司 | 抗-pd-l1抗体及它们用于增强t细胞功能的用途 |
LT3279215T (lt) | 2009-11-24 | 2020-04-10 | Medimmune Limited | Tiksliniai surišantys agentai prieš b7-h1 |
AU2012290121B2 (en) * | 2011-08-01 | 2015-11-26 | Genentech, Inc. | Methods of treating cancer using PD-1 axis binding antagonists and MEK inhibitors |
CN103987405B (zh) | 2011-11-28 | 2017-03-29 | 默克专利股份公司 | 抗pd‑l1抗体及其用途 |
SG11201407190TA (en) | 2012-05-15 | 2014-12-30 | Bristol Myers Squibb Co | Cancer immunotherapy by disrupting pd-1/pd-l1 signaling |
CN112552401B (zh) | 2013-09-13 | 2023-08-25 | 广州百济神州生物制药有限公司 | 抗pd1抗体及其作为治疗剂与诊断剂的用途 |
CN107106687A (zh) * | 2014-10-03 | 2017-08-29 | 诺华股份有限公司 | 组合治疗 |
SG10201810615VA (en) * | 2015-02-26 | 2019-01-30 | Merck Patent Gmbh | Pd-1 / pd-l1 inhibitors for the treatment of cancer |
CN107743495B (zh) * | 2015-03-23 | 2021-05-14 | 拜耳制药股份公司 | 抗ceacam6抗体及其用途 |
EP3560957A4 (en) * | 2016-11-14 | 2020-10-21 | Dinona | ANTIBODIES BINDING SPECIFICALLY TO CD66C AND ASSOCIATED USE |
-
2019
- 2019-11-07 CN CN201980074522.7A patent/CN112996814A/zh active Pending
- 2019-11-07 US US17/293,342 patent/US20220010017A1/en active Pending
- 2019-11-07 EP EP19797301.9A patent/EP3880705A1/en active Pending
- 2019-11-07 JP JP2021526335A patent/JP2022513036A/ja active Pending
- 2019-11-07 MX MX2021005686A patent/MX2021005686A/es unknown
- 2019-11-07 BR BR112021007448-1A patent/BR112021007448A2/pt not_active Application Discontinuation
- 2019-11-07 CA CA3119563A patent/CA3119563A1/en active Pending
- 2019-11-07 WO PCT/EP2019/080520 patent/WO2020099230A1/en unknown
- 2019-11-07 KR KR1020217014144A patent/KR20210091152A/ko unknown
- 2019-11-07 AU AU2019379261A patent/AU2019379261A1/en active Pending
- 2019-11-07 SG SG11202105078XA patent/SG11202105078XA/en unknown
-
2021
- 2021-05-10 IL IL283064A patent/IL283064A/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP3880705A1 (en) | 2021-09-22 |
US20220010017A1 (en) | 2022-01-13 |
BR112021007448A2 (pt) | 2021-10-26 |
KR20210091152A (ko) | 2021-07-21 |
AU2019379261A8 (en) | 2021-08-05 |
JP2022513036A (ja) | 2022-02-07 |
WO2020099230A1 (en) | 2020-05-22 |
AU2019379261A1 (en) | 2021-05-27 |
CN112996814A (zh) | 2021-06-18 |
CA3119563A1 (en) | 2020-05-22 |
SG11202105078XA (en) | 2021-06-29 |
IL283064A (en) | 2021-06-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2019014265A (es) | Tratamientos conjuntos triples con anticuerpos. | |
PH12019501253A1 (en) | Anti-tim-3 antibodies for combination with anti-pd-1 antibodies | |
MX2017015811A (es) | Tratamiento de cancer por bloqueo combinado de las trayectorias de señalizacion de muerte programada 1 (pd)-1 y receptor 4 de quimiocina c-x-c(cxcr4). | |
NZ753515A (en) | Methods for treatment of cancer comprising tigit-binding agents | |
CA2886433C (en) | Human monoclonal anti-pd-l1 antibodies and methods of use | |
PE20171180A1 (es) | Anticuerpos anti-pd-1 y sus metodos de uso | |
MY192822A (en) | An anti-ctla4 monoclonal antibody or antigen binding fragment thereof, a pharmaceutical composition and use | |
MX2016011155A (es) | Anticuerpo que une erbb-2 y erbb-3. | |
EA201891495A1 (ru) | Биспецифические анти-cd20/анти-cd3 антитела для лечения острого лимфобластного лейкоза | |
MX2018012651A (es) | Composiciones que comprenden coformulacion de anticuerpos anti-ligando-1 de muerte celular programada (pd-l1) y anti-antigeno-4 asociado a linfocitos t citotoxicos (ctla-4). | |
MX2017015039A (es) | Combinaciones de inmunoconjugado anti-cd37 y anticuerpo anti-cd20. | |
PH12020551661A1 (en) | Anti-pd-l1 antibody and use thereof | |
EA201890578A1 (ru) | Предотвращение, лечение и снижение (персистирующей) посттравматической головной боли | |
MX2019000727A (es) | Anticuerpos monoclonales humanizados que tienen como blanco ve-ptp (hptp-b). | |
MX2020008122A (es) | Anticuerpos anti-pd-1. | |
EA201990374A1 (ru) | Комбинация антитела против cd20, ингибитора pi3-киназы-дельта и антитела против pd-1 или против pd-l1 для лечения гематологических раков | |
MX2019010797A (es) | Uso de virus oncoliticos, solos o en combinacion con un inhibidor de punto de control, para el tratamiento del cancer. | |
MX2021005394A (es) | Co-formulaciones de anticuerpos anti-gen de activacion de linfocitos 3 (anti-lag3) y anticuerpos anti-muerte programada-1 (anti-pd-1). | |
MX2020002406A (es) | Anticuerpo anti-epha4. | |
MX2021004226A (es) | Terapia combinada contra el cáncer. | |
MX2019013753A (es) | Combinaciones de inmunoconjugados anti-folr1 y anticuerpo anti-pd-1. | |
EP4273165A3 (en) | Interferon beta antibodies and uses thereof | |
PH12020552006A1 (en) | Antibodies specific for cd3 and uses thereof | |
MX2020008730A (es) | Regímenes de dosificación de anticuerpo b7-h4. | |
MX2021010116A (es) | Anticuerpo anti-pd-l1 y uso de este. |