MX2021005560A - Terapia para el tratamiento del cancer con administracion intratumoral y/o intravenosa de un virus vaccinia ankara (mva) recombinante que codifica ligando 4-1bbl (cd137l) y/o ligando del cumulo o grupo de diferenciacion 40 (cd40l). - Google Patents

Terapia para el tratamiento del cancer con administracion intratumoral y/o intravenosa de un virus vaccinia ankara (mva) recombinante que codifica ligando 4-1bbl (cd137l) y/o ligando del cumulo o grupo de diferenciacion 40 (cd40l).

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Publication number
MX2021005560A
MX2021005560A MX2021005560A MX2021005560A MX2021005560A MX 2021005560 A MX2021005560 A MX 2021005560A MX 2021005560 A MX2021005560 A MX 2021005560A MX 2021005560 A MX2021005560 A MX 2021005560A MX 2021005560 A MX2021005560 A MX 2021005560A
Authority
MX
Mexico
Prior art keywords
ligand
1bbl
cd40l
intratumoral
cancer
Prior art date
Application number
MX2021005560A
Other languages
English (en)
Spanish (es)
Inventor
Henning Lauterbach
Maria Hinterberger
Echeverz Jose Medina
Original Assignee
Bavarian Nordic As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bavarian Nordic As filed Critical Bavarian Nordic As
Publication of MX2021005560A publication Critical patent/MX2021005560A/es

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    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4224—Molecules with a "CD" designation not provided for elsewhere
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MX2021005560A 2018-11-20 2019-11-20 Terapia para el tratamiento del cancer con administracion intratumoral y/o intravenosa de un virus vaccinia ankara (mva) recombinante que codifica ligando 4-1bbl (cd137l) y/o ligando del cumulo o grupo de diferenciacion 40 (cd40l). MX2021005560A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18207238 2018-11-20
US201962807720P 2019-02-19 2019-02-19
PCT/EP2019/081942 WO2020104531A1 (en) 2018-11-20 2019-11-20 Therapy for treating cancer with an intratumoral and/or intravenous administration of a recombinant mva encoding 4-1bbl (cd137l) and/or cd40l

Publications (1)

Publication Number Publication Date
MX2021005560A true MX2021005560A (es) 2021-06-23

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Application Number Title Priority Date Filing Date
MX2021005560A MX2021005560A (es) 2018-11-20 2019-11-20 Terapia para el tratamiento del cancer con administracion intratumoral y/o intravenosa de un virus vaccinia ankara (mva) recombinante que codifica ligando 4-1bbl (cd137l) y/o ligando del cumulo o grupo de diferenciacion 40 (cd40l).

Country Status (12)

Country Link
US (1) US12390515B2 (https=)
EP (1) EP3883599A1 (https=)
JP (1) JP7625518B2 (https=)
KR (1) KR20210094535A (https=)
CN (1) CN113056284A (https=)
AU (1) AU2019385665B2 (https=)
BR (1) BR112021009856A8 (https=)
CA (1) CA3119503A1 (https=)
IL (1) IL283187A (https=)
MX (1) MX2021005560A (https=)
SG (1) SG11202104918PA (https=)
WO (1) WO2020104531A1 (https=)

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KR102754876B1 (ko) * 2017-08-24 2025-01-13 버베리안 노딕 에이/에스 재조합 mva 및 항체의 정맥내 투여에 의한 암 치료를 위한 병용 요법
TWI852977B (zh) 2019-01-10 2024-08-21 美商健生生物科技公司 前列腺新抗原及其用途
KR20220115569A (ko) 2019-11-18 2022-08-17 얀센 바이오테크 인코포레이티드 돌연변이 calr 및 jak2에 기반한 백신 및 이의 용도
CN114867491B (zh) * 2019-11-20 2025-08-15 巴法里安诺迪克有限公司 用于肿瘤内和/或静脉内施用以治疗癌症的重组mva病毒
CN114929268A (zh) * 2019-11-20 2022-08-19 巴法里安诺迪克有限公司 4-1bbl辅助的重组修饰的安卡拉痘苗病毒(mva)的医疗用途
WO2021207171A1 (en) * 2020-04-06 2021-10-14 St. Jude Children's Research Hospital, Inc. B7-h3 chimeric antigen receptors
US12295997B2 (en) 2020-07-06 2025-05-13 Janssen Biotech, Inc. Prostate neoantigens and their uses
WO2022036495A1 (en) 2020-08-17 2022-02-24 Utc Therapeutics Inc. Lymphocytes-antigen presenting cells co-stimulators and uses thereof
WO2023076768A1 (en) * 2021-10-26 2023-05-04 Navicure Biopharmaceuticals Limited Combination therapies against cancer and infectious diseases
EP4452305A1 (en) * 2021-12-23 2024-10-30 Bavarian Nordic A/S Recombinant mva viruses for intraperitoneal administration for treating cancer
US20250049903A1 (en) 2021-12-23 2025-02-13 Bavarian Nordic A/S Therapy for Modulating Immune Response with Recombinant MVA Encoding IL-12
CN117004579B (zh) * 2023-06-29 2024-11-15 苏州恩立维生物科技有限公司 重组溶瘤牛痘病毒及其应用

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