MX2021004937A - Glicerolesteres del acido nicotinico bioenergetico, composiciones y metodos para utilizar el mismo. - Google Patents

Glicerolesteres del acido nicotinico bioenergetico, composiciones y metodos para utilizar el mismo.

Info

Publication number
MX2021004937A
MX2021004937A MX2021004937A MX2021004937A MX2021004937A MX 2021004937 A MX2021004937 A MX 2021004937A MX 2021004937 A MX2021004937 A MX 2021004937A MX 2021004937 A MX2021004937 A MX 2021004937A MX 2021004937 A MX2021004937 A MX 2021004937A
Authority
MX
Mexico
Prior art keywords
nicotinic acid
acid glycerol
methods
cellular
bioenergetic
Prior art date
Application number
MX2021004937A
Other languages
English (en)
Inventor
Bijan Harichian
Van Au
Jose Guillermo Rosa
John Chun-Sing Nip
Original Assignee
Unilever Ip Holdings B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Ip Holdings B V filed Critical Unilever Ip Holdings B V
Publication of MX2021004937A publication Critical patent/MX2021004937A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/062—Oil-in-water emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describen compuestos de gliceroléster del ácido nicotínico (NAE) novedosos; composiciones para el cuidado personal tópica que contienen NAE; y métodos para modular o activar los niveles de AMPK celulares; y para aumentar los bioenergéticos celulares de la piel. Se describen el uso de uno o más de los compuestos de gliceroléster del ácido nicotínico para modular o activar los niveles de AMPK celulares; y para aumentar los bioenergéticos celulares de la piel. Se describen el uso de un agente benéfico para la piel que comprende ciertos compuestos de gliceroléster del ácido nicotínico en la fabricación de una composición tópica para el cuidado personal para modular o activar los niveles de AMPK celulares; y para aumentar los bioenergéticos celulares de la piel.
MX2021004937A 2018-11-02 2019-10-29 Glicerolesteres del acido nicotinico bioenergetico, composiciones y metodos para utilizar el mismo. MX2021004937A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18204203 2018-11-02
PCT/EP2019/079543 WO2020089236A1 (en) 2018-11-02 2019-10-29 Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same

Publications (1)

Publication Number Publication Date
MX2021004937A true MX2021004937A (es) 2021-06-08

Family

ID=64426633

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021004937A MX2021004937A (es) 2018-11-02 2019-10-29 Glicerolesteres del acido nicotinico bioenergetico, composiciones y metodos para utilizar el mismo.

Country Status (5)

Country Link
US (1) US11767314B2 (es)
EP (1) EP3873415A1 (es)
CN (1) CN112955115B (es)
MX (1) MX2021004937A (es)
WO (1) WO2020089236A1 (es)

Family Cites Families (52)

* Cited by examiner, † Cited by third party
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Also Published As

Publication number Publication date
CN112955115B (zh) 2023-06-30
US20210380564A1 (en) 2021-12-09
US11767314B2 (en) 2023-09-26
WO2020089236A1 (en) 2020-05-07
EP3873415A1 (en) 2021-09-08
CN112955115A (zh) 2021-06-11

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