MX2021003959A - Composicion para modular genes responsables de las funciones generales de la piel, metodo para modular la expresion de genes responsables de las funciones generales de la piel y uso de un extracto vegetal. - Google Patents

Composicion para modular genes responsables de las funciones generales de la piel, metodo para modular la expresion de genes responsables de las funciones generales de la piel y uso de un extracto vegetal.

Info

Publication number
MX2021003959A
MX2021003959A MX2021003959A MX2021003959A MX2021003959A MX 2021003959 A MX2021003959 A MX 2021003959A MX 2021003959 A MX2021003959 A MX 2021003959A MX 2021003959 A MX2021003959 A MX 2021003959A MX 2021003959 A MX2021003959 A MX 2021003959A
Authority
MX
Mexico
Prior art keywords
modulating
genes responsible
general skin
skin functions
expression
Prior art date
Application number
MX2021003959A
Other languages
English (en)
Inventor
Fabiana Paes
Romeu Clarissa Capelas
Oliveira Reis Eduardo Alexandre De
Savietto Joice Panzarin
Moncayo Priscila Carollo
Simone Andrea Emidio
De Moura Soraya Baione
Daniela Zimbardi
De Oliveira Ricardo Augusto Santos
D'annolfo Kassandra Tadini
Original Assignee
Natura Cosmeticos Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BR102016011807-7A external-priority patent/BR102016011807A2/pt
Priority claimed from BR102016011810-7A external-priority patent/BR102016011810A2/pt
Priority claimed from BR102016011816-6A external-priority patent/BR102016011816A2/pt
Priority claimed from BR102016011821-2A external-priority patent/BR102016011821A2/pt
Priority claimed from BR102016022683-0A external-priority patent/BR102016022683A2/pt
Priority claimed from BR102016022681-3A external-priority patent/BR102016022681A2/pt
Priority claimed from BR102016022679-1A external-priority patent/BR102016022679A2/pt
Priority claimed from BR102016022682-1A external-priority patent/BR102016022682A2/pt
Application filed by Natura Cosmeticos Sa filed Critical Natura Cosmeticos Sa
Publication of MX2021003959A publication Critical patent/MX2021003959A/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/164Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/22Anacardiaceae (Sumac family), e.g. smoketree, sumac or poison oak
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/76Salicaceae (Willow family), e.g. poplar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10General cosmetic use

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Birds (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

La presente invención se refiere a composiciones para modular genes responsables de las funciones generales de la piel que comprenden al menos un extracto vegetal y al menos un vehículo cosméticamente aceptable, así como a un método para modular la expresión de los genes responsables de las funciones generales de la piel, y uso del extracto vegetal en la preparación de una composición para modular genes responsables de las funciones generales de la piel.
MX2021003959A 2016-05-24 2018-11-23 Composicion para modular genes responsables de las funciones generales de la piel, metodo para modular la expresion de genes responsables de las funciones generales de la piel y uso de un extracto vegetal. MX2021003959A (es)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
BR102016011807-7A BR102016011807A2 (pt) 2016-05-24 2016-05-24 Composition for modulation of genes responsible for general skin functions, method for modulating expression of genes responsible for general skin functions and use of camellia sinensis and espilantol
BR102016011810-7A BR102016011810A2 (pt) 2016-05-24 2016-05-24 Composition for the modulation of genes responsible for general skin functions, method for modulating expression of genes responsible for general skin functions and use of jatobá xyloglucan and a sodium cocoil amino acids and sarcosin and potassium aspartate and magnesium aspartate mix
BR102016011816-6A BR102016011816A2 (pt) 2016-05-24 2016-05-24 Composition for the modulation of genes responsible for general skin functions, method for modulating expression of genes responsible for general skin functions and use of cases sylvestris, schinus terebinthifolius and paeonia albiflora
BR102016011821-2A BR102016011821A2 (pt) 2016-05-24 2016-05-24 Composition for the modulation of genes responsible for general skin functions, method for modulating expression of genes responsible for general skin functions and use of ceramidas de maracujá and cichorium intybus
BR102016022683-0A BR102016022683A2 (pt) 2016-09-29 2016-09-29 Composição para a modulação de genes responsáveis pelas funções gerais da pele, método para a modulação da expressão de genes responsáveis pelas funções gerais da pele e uso de spilol e ácido hialurônico
BR102016022681-3A BR102016022681A2 (pt) 2016-09-29 2016-09-29 Composição para a modulação de genes responsáveis pelas funções gerais da pele, método para a modulação da expressão de genes responsáveis pelas funções gerais da pele e uso de hymenaea courbaril, paeonia albiflora, secale cereale e avena sativa
BR102016022679-1A BR102016022679A2 (pt) 2016-09-29 2016-09-29 Composição para a modulação de genes responsáveis pelas funções gerais da pele, método para a modulação da expressão de genes responsáveis pelas funções gerais da pele e uso de schinus terebinthfolius e cafeína
BR102016022682-1A BR102016022682A2 (pt) 2016-09-29 2016-09-29 Composição para a modulação de genes responsáveis pelas funções gerais da pele, método para a modulação da expressão de genes responsáveis pelas funções gerais da pele e uso de casearia sylvestris, schinus terebinthfolius e ácido hialurônico

Publications (1)

Publication Number Publication Date
MX2021003959A true MX2021003959A (es) 2021-05-27

Family

ID=60411020

Family Applications (6)

Application Number Title Priority Date Filing Date
MX2018014431A MX2018014431A (es) 2016-05-24 2017-05-24 Composicion para modular genes responsables de las funciones generales de la piel, metodo para modular la expresion de genes responsables de las funciones generales de la piel y uso de un extracto vegetal.
MX2021003952A MX2021003952A (es) 2016-05-24 2017-05-24 Una composición que comprende una combinación de extracto de schinus terebinthifolius y cafeína.
MX2021003950A MX2021003950A (es) 2016-05-24 2018-11-23 Composicion para modular genes responsables de las funciones generales de la piel, metodo para modular la expresion de genes responsables de las funciones generales de la piel y uso de un extracto vegetal.
MX2021003959A MX2021003959A (es) 2016-05-24 2018-11-23 Composicion para modular genes responsables de las funciones generales de la piel, metodo para modular la expresion de genes responsables de las funciones generales de la piel y uso de un extracto vegetal.
MX2021003951A MX2021003951A (es) 2016-05-24 2018-11-23 Composicion para modular genes responsables de las funciones generales de la piel, metodo para modular la expresion de genes responsables de las funciones generales de la piel y uso de un extracto vegetal.
MX2021003953A MX2021003953A (es) 2016-05-24 2018-11-23 Composicion para modular genes responsables de las funciones generales de la piel, metodo para modular la expresion de genes responsables de las funciones generales de la piel y uso de un extracto vegetal.

Family Applications Before (3)

Application Number Title Priority Date Filing Date
MX2018014431A MX2018014431A (es) 2016-05-24 2017-05-24 Composicion para modular genes responsables de las funciones generales de la piel, metodo para modular la expresion de genes responsables de las funciones generales de la piel y uso de un extracto vegetal.
MX2021003952A MX2021003952A (es) 2016-05-24 2017-05-24 Una composición que comprende una combinación de extracto de schinus terebinthifolius y cafeína.
MX2021003950A MX2021003950A (es) 2016-05-24 2018-11-23 Composicion para modular genes responsables de las funciones generales de la piel, metodo para modular la expresion de genes responsables de las funciones generales de la piel y uso de un extracto vegetal.

Family Applications After (2)

Application Number Title Priority Date Filing Date
MX2021003951A MX2021003951A (es) 2016-05-24 2018-11-23 Composicion para modular genes responsables de las funciones generales de la piel, metodo para modular la expresion de genes responsables de las funciones generales de la piel y uso de un extracto vegetal.
MX2021003953A MX2021003953A (es) 2016-05-24 2018-11-23 Composicion para modular genes responsables de las funciones generales de la piel, metodo para modular la expresion de genes responsables de las funciones generales de la piel y uso de un extracto vegetal.

Country Status (5)

Country Link
US (1) US20200315950A1 (es)
BR (1) BR112018074219A2 (es)
CL (8) CL2018003354A1 (es)
MX (6) MX2018014431A (es)
WO (1) WO2017201597A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR102017016427A2 (pt) * 2017-07-31 2019-03-26 Natura Cosméticos S.A. Método para avaliar hidratação bioativa de um ingrediente ou mistura de ingredientes, composições cosméticas para a modulação de genes responsáveis pela hidratação bioativa da pele e método para a modulação da expressão de genes responsáveis pela hidratação bioativa da pele
EP4072513A1 (en) 2019-12-10 2022-10-19 Mary Kay, Inc. Herbal cosmetic composition for treating skin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2626469B1 (fr) * 1988-01-29 1990-07-20 Diot Michel Nouvelles preparations cosmetiques contenant un extrait des parties aeriennes de cichorium intybus l
JP2001322940A (ja) * 2000-05-12 2001-11-20 Kao Corp カテプシンd産生促進剤
JP2003055190A (ja) * 2001-08-07 2003-02-26 Koei Kogyo Kk コラゲナーゼ阻害剤及び抗老化用化粧料
FR3010313A1 (fr) * 2013-09-09 2015-03-13 Natura Cosmeticos Sa Composition comprenant un extrait de guacatonga et un extrait d'aroeira, son utilisation et methode pour empecher et/ou traiter les signes causes par le vieillissement de la peau

Also Published As

Publication number Publication date
CL2020002642A1 (es) 2020-12-18
CL2020002646A1 (es) 2020-12-18
CL2020002647A1 (es) 2020-12-18
CL2020002641A1 (es) 2020-12-18
MX2021003952A (es) 2022-07-19
MX2021003953A (es) 2021-05-27
MX2021003950A (es) 2021-05-27
CL2020002644A1 (es) 2020-12-18
CL2018003354A1 (es) 2019-08-23
CL2020002639A1 (es) 2020-12-18
WO2017201597A1 (pt) 2017-11-30
CL2020002643A1 (es) 2020-12-18
BR112018074219A2 (pt) 2019-03-06
MX2021003951A (es) 2021-05-27
MX2018014431A (es) 2019-03-28
US20200315950A1 (en) 2020-10-08

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