MX2021003034A - Sales de compuestos de cicloserina y aplicaciones de estas. - Google Patents
Sales de compuestos de cicloserina y aplicaciones de estas.Info
- Publication number
- MX2021003034A MX2021003034A MX2021003034A MX2021003034A MX2021003034A MX 2021003034 A MX2021003034 A MX 2021003034A MX 2021003034 A MX2021003034 A MX 2021003034A MX 2021003034 A MX2021003034 A MX 2021003034A MX 2021003034 A MX2021003034 A MX 2021003034A
- Authority
- MX
- Mexico
- Prior art keywords
- salts
- formula
- compound
- cycloserine
- applications
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 4
- DYDCUQKUCUHJBH-UWTATZPHSA-N D-Cycloserine Chemical class N[C@@H]1CONC1=O DYDCUQKUCUHJBH-UWTATZPHSA-N 0.000 title 1
- DYDCUQKUCUHJBH-UHFFFAOYSA-N D-Cycloserine Natural products NC1CONC1=O DYDCUQKUCUHJBH-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229960003077 cycloserine Drugs 0.000 abstract 2
- -1 cycloserine compound Chemical class 0.000 abstract 2
- 150000001450 anions Chemical group 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 150000001768 cations Chemical group 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 201000008827 tuberculosis Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/30—Other Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se proporcionan en la presente sales de la Fórmula [A][B], en donde [A] es una forma catiónica de un compuesto de cicloserina y [B] es una forma aniónica de un compuesto de la Fórmula (I), en donde la relación entre el compuesto de cicloserina y el compuesto de la Fórmula (I) varía de 10:1 a 1:10; las sales descritas en la presente tienen propiedades mejoradas, que incluyen una estabilidad aumentada considerablemente y una higroscopicidad reducida; también se proporcionan en la presente métodos para tratar y/o reducir el riesgo de un trastorno neuropsiquiátrico y/o una enfermedad infecciosa bacteriana (por ejemplo, tuberculosis), que comprenden administrar a un sujeto que lo necesite una composición que comprende sales de la Fórmula [A][B] descrita en la presente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16/130,836 US10485790B1 (en) | 2018-09-13 | 2018-09-13 | Salts of cycloserine compounds and applications thereof |
PCT/CN2019/105564 WO2020052620A1 (en) | 2018-09-13 | 2019-09-12 | Salts of cycloserine compounds and applications thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021003034A true MX2021003034A (es) | 2021-05-27 |
Family
ID=68617782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021003034A MX2021003034A (es) | 2018-09-13 | 2019-09-12 | Sales de compuestos de cicloserina y aplicaciones de estas. |
Country Status (10)
Country | Link |
---|---|
US (2) | US10485790B1 (es) |
EP (1) | EP3849547A4 (es) |
JP (1) | JP7539709B2 (es) |
KR (1) | KR20210061348A (es) |
CN (1) | CN112714645A (es) |
CA (1) | CA3111655A1 (es) |
IL (1) | IL281229A (es) |
MX (1) | MX2021003034A (es) |
TW (1) | TWI784198B (es) |
WO (1) | WO2020052620A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10485790B1 (en) * | 2018-09-13 | 2019-11-26 | Syneurx International (Taiwan) Corp. | Salts of cycloserine compounds and applications thereof |
WO2023171106A1 (ja) * | 2022-03-08 | 2023-09-14 | ソシウム株式会社 | Tdp-43の凝集の抑制剤、tdp-43が過剰発現している細胞の細胞死の抑制剤、及びtdp-43の凝集を伴う疾患の治療又は予防剤 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2840565A (en) * | 1954-12-23 | 1958-06-24 | Merck & Co Inc | Optical isomers of 4-amino-3-isoxazolidone |
CS219409B1 (cs) * | 1964-03-06 | 1983-03-25 | Jiri Michalsky | Způsob výroby nových opticky aktivních a racemických derivátů kyseliny a-amino-ijS-aminooxypropionové |
KR20070007276A (ko) * | 2003-12-29 | 2007-01-15 | 제이슨 맥데빗 | 재발성 의학적 증상을 치료하기 위한 조성물 및 방법 |
GB0813211D0 (en) * | 2008-07-18 | 2008-08-27 | E Therapeutics Plc | Antibacterial combination therapy for the treatment of gram positive bacterial infections |
CN101596190A (zh) * | 2009-07-07 | 2009-12-09 | 山东大学 | D-环丝氨酸的制药用途 |
CN102382072A (zh) * | 2011-11-23 | 2012-03-21 | 济南诚汇双达化工有限公司 | 一种d-环丝氨酸的精制方法 |
CN105476976B (zh) * | 2015-12-22 | 2018-09-25 | 广州瑞尔医药科技有限公司 | 药物组合物及其制备方法和应用 |
US10485790B1 (en) * | 2018-09-13 | 2019-11-26 | Syneurx International (Taiwan) Corp. | Salts of cycloserine compounds and applications thereof |
-
2018
- 2018-09-13 US US16/130,836 patent/US10485790B1/en active Active
-
2019
- 2019-09-12 EP EP19860521.4A patent/EP3849547A4/en active Pending
- 2019-09-12 WO PCT/CN2019/105564 patent/WO2020052620A1/en unknown
- 2019-09-12 KR KR1020217008088A patent/KR20210061348A/ko not_active Application Discontinuation
- 2019-09-12 CN CN201980060025.1A patent/CN112714645A/zh active Pending
- 2019-09-12 MX MX2021003034A patent/MX2021003034A/es unknown
- 2019-09-12 US US17/275,794 patent/US20220047561A1/en active Pending
- 2019-09-12 JP JP2021513786A patent/JP7539709B2/ja active Active
- 2019-09-12 CA CA3111655A patent/CA3111655A1/en active Pending
- 2019-09-12 TW TW108133040A patent/TWI784198B/zh active
-
2021
- 2021-03-03 IL IL281229A patent/IL281229A/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP3849547A1 (en) | 2021-07-21 |
CA3111655A1 (en) | 2020-03-19 |
CN112714645A (zh) | 2021-04-27 |
US10485790B1 (en) | 2019-11-26 |
EP3849547A4 (en) | 2022-06-22 |
TWI784198B (zh) | 2022-11-21 |
US20220047561A1 (en) | 2022-02-17 |
TW202023546A (zh) | 2020-07-01 |
WO2020052620A1 (en) | 2020-03-19 |
JP7539709B2 (ja) | 2024-08-26 |
KR20210061348A (ko) | 2021-05-27 |
JP2022500397A (ja) | 2022-01-04 |
IL281229A (en) | 2021-04-29 |
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