MX2021002561A - Expresion recombinante de la fumonisina amina oxidasa. - Google Patents

Expresion recombinante de la fumonisina amina oxidasa.

Info

Publication number
MX2021002561A
MX2021002561A MX2021002561A MX2021002561A MX2021002561A MX 2021002561 A MX2021002561 A MX 2021002561A MX 2021002561 A MX2021002561 A MX 2021002561A MX 2021002561 A MX2021002561 A MX 2021002561A MX 2021002561 A MX2021002561 A MX 2021002561A
Authority
MX
Mexico
Prior art keywords
fumonisin
products
amine oxidase
oxidase activity
heterologous polypeptide
Prior art date
Application number
MX2021002561A
Other languages
English (en)
Inventor
Christopher Peter Garnham
Mark William Sumarah
Justin Beneteau Renaud
Patrick Gordon Telmer
Shane Gordon Butler
Original Assignee
Her Majesty The Queen In Right Of Canada As Represented By The Mini Of Agriculture And Agri Food
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Her Majesty The Queen In Right Of Canada As Represented By The Mini Of Agriculture And Agri Food filed Critical Her Majesty The Queen In Right Of Canada As Represented By The Mini Of Agriculture And Agri Food
Publication of MX2021002561A publication Critical patent/MX2021002561A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
    • A23L5/25—Removal of unwanted matter, e.g. deodorisation or detoxification using enzymes
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D8/00—Methods for preparing or baking dough
    • A21D8/02—Methods for preparing dough; Treating dough prior to baking
    • A21D8/04—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes
    • A21D8/047—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes with yeasts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
    • A23K10/38—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material from distillers' or brewers' waste
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A62—LIFE-SAVING; FIRE-FIGHTING
    • A62D—CHEMICAL MEANS FOR EXTINGUISHING FIRES OR FOR COMBATING OR PROTECTING AGAINST HARMFUL CHEMICAL AGENTS; CHEMICAL MATERIALS FOR USE IN BREATHING APPARATUS
    • A62D3/00—Processes for making harmful chemical substances harmless or less harmful, by effecting a chemical change in the substances
    • A62D3/02—Processes for making harmful chemical substances harmless or less harmful, by effecting a chemical change in the substances by biological methods, i.e. processes using enzymes or microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/002—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with a cytochrome as acceptor (1.4.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/02—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with a cytochrome as acceptor (1.4.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/66—Aspergillus
    • C12R2001/685—Aspergillus niger
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/85—Saccharomyces
    • C12R2001/865—Saccharomyces cerevisiae
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87—Re-use of by-products of food processing for fodder production

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Animal Husbandry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Physiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Business, Economics & Management (AREA)
  • Emergency Management (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Las fumonisinas son un tipo de micotoxinas que contaminan diferentes productos, por ejemplo, piensos y productos alimenticios, incluidos los productos a base de maíz, lo que puede provocar graves riesgos para la salud de los seres humanos y del ganado. Los métodos actuales para destoxificar productos contaminados con fumonisinas son complejos y costosos. La presente descripción proporciona una célula anfitriona microbiana recombinante que expresa un polipéptido heterólogo que tiene actividad fumonisina amina oxidasa, donde la célula anfitriona microbiana recombinante comprende una molécula de ácido nucleico heteróloga que codifica el polipéptido heterólogo que tiene actividad fumonisina amina oxidasa, una variante de esta o un fragmento de esta. El polipéptido heterólogo que tiene actividad fumonisina amina oxidasa se puede usar para destoxificar una micotoxina fumonisina presente en piensos y productos alimenticios, por ejemplo de cereales y productos derivados de cereales.
MX2021002561A 2018-09-05 2019-09-04 Expresion recombinante de la fumonisina amina oxidasa. MX2021002561A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862727217P 2018-09-05 2018-09-05
PCT/CA2019/051230 WO2020047656A1 (en) 2018-09-05 2019-09-04 Recombinant expression of fumonisin amine oxidase

Publications (1)

Publication Number Publication Date
MX2021002561A true MX2021002561A (es) 2021-11-12

Family

ID=69722723

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021002561A MX2021002561A (es) 2018-09-05 2019-09-04 Expresion recombinante de la fumonisina amina oxidasa.

Country Status (7)

Country Link
US (1) US20210337838A1 (es)
EP (1) EP3847249A4 (es)
BR (1) BR112021003985A2 (es)
CA (1) CA3110572A1 (es)
MX (1) MX2021002561A (es)
PH (1) PH12021550463A1 (es)
WO (1) WO2020047656A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210403841A1 (en) 2020-03-12 2021-12-30 Poet Research, Inc. Enzymatic degradation of mycotoxins during grain processing
CN117835830A (zh) * 2021-09-09 2024-04-05 波特研究公司 霉菌毒素在发酵期间和发酵后的酶促降解
CN113817696B (zh) * 2021-09-27 2023-09-19 天津科技大学 一种胺氧化酶asao、制备方法和应用
CN113817695B (zh) * 2021-09-27 2023-09-01 天津科技大学 一种胺氧化酶ndao、制备方法和应用
WO2023144753A2 (en) 2022-01-26 2023-08-03 Danstar Ferment Ag Recombinant expression of fumonisin esterase, compositions and uses thereof
WO2024044249A1 (en) * 2022-08-23 2024-02-29 Poet Research, Inc. Methods and systems for propagating microorganisms for mitigating mycotoxin contamination, and related systems and methods
EP4357460A1 (en) * 2022-10-21 2024-04-24 Consejo Superior De Investigaciones Científicas Fumonisin enzymatic degradation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002520058A (ja) * 1998-07-15 2002-07-09 パイオニア ハイ−ブレッド インターナショナル， インコーポレイテッド アミノポリオールアミンオキシダーゼポリヌクレオチド類および関連のポリペプチド類ならびに使用方法
US7611897B2 (en) * 2001-02-06 2009-11-03 Pioneer Hi-Bred International, Inc. AP1 amine oxidase variants

Also Published As

Publication number Publication date
PH12021550463A1 (en) 2021-11-22
BR112021003985A2 (pt) 2021-05-25
EP3847249A1 (en) 2021-07-14
CA3110572A1 (en) 2020-03-12
EP3847249A4 (en) 2022-08-03
WO2020047656A1 (en) 2020-03-12
US20210337838A1 (en) 2021-11-04

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