MX2020013669A - Formulaciones para vectores adenovirales de simio que tienen estabilidad mejorada. - Google Patents
Formulaciones para vectores adenovirales de simio que tienen estabilidad mejorada.Info
- Publication number
- MX2020013669A MX2020013669A MX2020013669A MX2020013669A MX2020013669A MX 2020013669 A MX2020013669 A MX 2020013669A MX 2020013669 A MX2020013669 A MX 2020013669A MX 2020013669 A MX2020013669 A MX 2020013669A MX 2020013669 A MX2020013669 A MX 2020013669A
- Authority
- MX
- Mexico
- Prior art keywords
- formulations
- adenoviral vectors
- enhanced stability
- simian adenoviral
- simian
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10041—Use of virus, viral particle or viral elements as a vector
- C12N2710/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
La invención se refiere a formulaciones líquidas de adenovirus de simio y métodos para obtener las formulaciones. Las formulaciones comprenden un azúcar amorfo, succinato de Vitamina E y albúmina de suero humano recombinante en una solución amortiguada.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18179977.6A EP3587581A1 (en) | 2018-06-26 | 2018-06-26 | Formulations for simian adenoviral vectors having enhanced storage stability |
PCT/IB2019/055347 WO2020003126A1 (en) | 2018-06-26 | 2019-06-25 | Formulations for simian adenoviral vectors having enhanced stability |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020013669A true MX2020013669A (es) | 2021-03-02 |
Family
ID=62837592
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020013669A MX2020013669A (es) | 2018-06-26 | 2019-06-25 | Formulaciones para vectores adenovirales de simio que tienen estabilidad mejorada. |
Country Status (8)
Country | Link |
---|---|
US (1) | US20210207171A1 (es) |
EP (2) | EP3587581A1 (es) |
JP (1) | JP7279086B2 (es) |
CN (1) | CN112469831A (es) |
BR (1) | BR112020025620A2 (es) |
CA (1) | CA3104601A1 (es) |
MX (1) | MX2020013669A (es) |
WO (1) | WO2020003126A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW202043256A (zh) | 2019-01-10 | 2020-12-01 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
JP2022536137A (ja) * | 2019-06-11 | 2022-08-12 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 粘膜ワクチン製剤 |
PE20221182A1 (es) | 2019-11-18 | 2022-08-05 | Janssen Biotech Inc | Vacunas basadas en calr y jak2 mutantes y sus usos |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU228327B1 (en) | 2001-06-22 | 2013-03-28 | Wistar Inst | Methods of inducing a cytotoxic immune response and recombinant simian adenovirus compositions useful therein |
ATE449105T1 (de) | 2004-01-23 | 2009-12-15 | Angeletti P Ist Richerche Bio | Impfstoffträger für schimpansen-adenovirus |
SG172935A1 (en) | 2009-02-02 | 2011-08-29 | Okairos Ag | Simian adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof |
WO2011103114A1 (en) * | 2010-02-17 | 2011-08-25 | Hememics Biotechnologies, Inc. | Preservation solutions for biologics and methods related thereto |
EP2764014B1 (en) | 2011-10-05 | 2022-02-09 | GenVec, Inc. | Adenoviral vectors and methods of use |
IN2014DN03005A (es) | 2011-10-05 | 2015-05-08 | Genvec Inc | |
US9629906B2 (en) | 2011-10-05 | 2017-04-25 | Genvec, Inc. | Affenadenovirus (gorilla) or adenoviral vectors and methods of use |
CN108025058B (zh) | 2015-06-12 | 2022-12-16 | 葛兰素史密丝克莱恩生物有限公司 | 腺病毒多核苷酸和多肽 |
GB201513010D0 (en) | 2015-07-23 | 2015-09-09 | Glaxosmithkline Biolog Sa | Novel formulation |
GB201701239D0 (en) * | 2017-01-25 | 2017-03-08 | Glaxosmithkline Biologicals Sa | Novel formulation |
KR102582561B1 (ko) | 2017-07-05 | 2023-09-26 | 노우스콤 아게 | 비인간 대형 유인원 아데노바이러스 핵산-서열 및 아미노산-서열, 이를 포함하는 벡터 및 그의 용도 |
-
2018
- 2018-06-26 EP EP18179977.6A patent/EP3587581A1/en not_active Ceased
-
2019
- 2019-06-25 CN CN201980050157.6A patent/CN112469831A/zh active Pending
- 2019-06-25 EP EP19762474.5A patent/EP3814511A1/en active Pending
- 2019-06-25 WO PCT/IB2019/055347 patent/WO2020003126A1/en unknown
- 2019-06-25 MX MX2020013669A patent/MX2020013669A/es unknown
- 2019-06-25 JP JP2020571758A patent/JP7279086B2/ja active Active
- 2019-06-25 BR BR112020025620-0A patent/BR112020025620A2/pt unknown
- 2019-06-25 US US17/251,518 patent/US20210207171A1/en not_active Abandoned
- 2019-06-25 CA CA3104601A patent/CA3104601A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2021529178A (ja) | 2021-10-28 |
EP3814511A1 (en) | 2021-05-05 |
JP7279086B2 (ja) | 2023-05-22 |
US20210207171A1 (en) | 2021-07-08 |
CN112469831A (zh) | 2021-03-09 |
EP3587581A1 (en) | 2020-01-01 |
WO2020003126A1 (en) | 2020-01-02 |
CA3104601A1 (en) | 2020-01-02 |
BR112020025620A2 (pt) | 2021-03-23 |
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