MX2020003786A - Composiciones orales para el tratamiento de reflujo gastroesofagico. - Google Patents
Composiciones orales para el tratamiento de reflujo gastroesofagico.Info
- Publication number
- MX2020003786A MX2020003786A MX2020003786A MX2020003786A MX2020003786A MX 2020003786 A MX2020003786 A MX 2020003786A MX 2020003786 A MX2020003786 A MX 2020003786A MX 2020003786 A MX2020003786 A MX 2020003786A MX 2020003786 A MX2020003786 A MX 2020003786A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- oral compositions
- gastroesophageal reflux
- composition
- gastroesophageal
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 208000021302 gastroesophageal reflux disease Diseases 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 abstract 1
- 229920001287 Chondroitin sulfate Polymers 0.000 abstract 1
- 229920002000 Xyloglucan Polymers 0.000 abstract 1
- 229940059329 chondroitin sulfate Drugs 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003232 mucoadhesive effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención describe una composición mucoadhesiva que comprende sulfato de condroitina, xiloglucano y glicerol para uso en el tratamiento y prevención de flujo gastroesofagico; también se describe un procedimiento para la preparación de tal composición, una forma de dosificación para su administración y un kit que comprende la misma.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT102017000108526A IT201700108526A1 (it) | 2017-09-28 | 2017-09-28 | Composizioni orali per il trattamento del refluso gastroesofageo. |
PCT/EP2018/075200 WO2019063363A1 (en) | 2017-09-28 | 2018-09-18 | ORAL COMPOSITIONS FOR THE TREATMENT OF GASTRO-ESOPHAGEAL REFLUX |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020003786A true MX2020003786A (es) | 2020-08-03 |
Family
ID=61024911
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020003786A MX2020003786A (es) | 2017-09-28 | 2018-09-18 | Composiciones orales para el tratamiento de reflujo gastroesofagico. |
Country Status (7)
Country | Link |
---|---|
US (1) | US11241452B2 (es) |
EP (1) | EP3687494A1 (es) |
CN (2) | CN111093628B (es) |
EA (1) | EA202090827A1 (es) |
IT (1) | IT201700108526A1 (es) |
MX (1) | MX2020003786A (es) |
WO (1) | WO2019063363A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT202000022471A1 (it) * | 2020-09-23 | 2022-03-23 | Sofar Swiss Sa | Composizioni comprendenti una condroitina vegetale o un suo analogo e loro uso nel trattamento disturbi della mucosa del tratto orale, faringo-laringeo e/o gastro-esofageo |
TWI777673B (zh) * | 2021-07-16 | 2022-09-11 | 陳昭誠 | 由β-1-4-葡聚醣形成之纖維於製備用於治療或預防胃食道逆流之組成物之用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU7201998A (en) * | 1997-05-06 | 1998-11-27 | Zhi Liu | Drug delivery system |
GB9910212D0 (en) | 1999-05-05 | 1999-06-30 | Reckitt & Colmann Prod Ltd | Improvements in or relating to organic compositions |
US7504387B2 (en) | 2002-10-16 | 2009-03-17 | Arthrodynamic Technologies, Animal Health Division, Inc. | Glycosaminoglycan composition and method for treatment and prevention of interstitial cystitis |
GB2398496A (en) * | 2003-02-20 | 2004-08-25 | Reckitt Benckiser Healthcare | Suspensions of water-swellable polymer particles which are substantially water-free or contain insufficient water to fully swell the particles |
ITBO20050388A1 (it) | 2005-06-06 | 2006-12-07 | Alfa Wassermann Spa | Formulazione mucoadesive utili in dispositivi medici in preparazioni farmaceutiche |
DE202008017456U1 (de) * | 2007-08-27 | 2009-08-27 | Biogenerix Ag | Flüssig-Formulierung von G-CSF-Konjugaten |
US9241953B2 (en) * | 2008-05-13 | 2016-01-26 | Apharm S.R.L. | Glycosaminoglycan oral use and compositions |
PT2296670E (pt) | 2008-05-13 | 2013-03-25 | Apharm Srl | Utilização oral de glicosaminoglicana e composições |
EP2208500A1 (en) * | 2009-01-16 | 2010-07-21 | Bionap S.r.L. | Compositions for the treatment of gerd (gastroesophageal reflux disease) |
PT2435021E (pt) | 2009-05-25 | 2013-09-30 | Sofar Swiss Sa | Utilização de uma combinação fixa de glicosaminoglicano e composição mastigável compreendendo a referida combinação fixa |
IT1397132B1 (it) * | 2009-12-01 | 2013-01-04 | Alfa Wassermann Spa | Composizioni comprendenti antiinfiammatori non steroidei. |
JP2014501258A (ja) * | 2010-12-23 | 2014-01-20 | コルゲート・パーモリブ・カンパニー | 構造化剤を含む流体組成物 |
-
2017
- 2017-09-28 IT IT102017000108526A patent/IT201700108526A1/it unknown
-
2018
- 2018-09-18 EA EA202090827A patent/EA202090827A1/ru unknown
- 2018-09-18 WO PCT/EP2018/075200 patent/WO2019063363A1/en unknown
- 2018-09-18 US US16/349,711 patent/US11241452B2/en active Active
- 2018-09-18 MX MX2020003786A patent/MX2020003786A/es unknown
- 2018-09-18 CN CN201880059051.8A patent/CN111093628B/zh active Active
- 2018-09-18 EP EP18770024.0A patent/EP3687494A1/en active Pending
- 2018-09-18 CN CN202311516607.0A patent/CN117503794A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2019063363A1 (en) | 2019-04-04 |
IT201700108526A1 (it) | 2019-03-28 |
CN111093628B (zh) | 2023-11-17 |
CN117503794A (zh) | 2024-02-06 |
EP3687494A1 (en) | 2020-08-05 |
US11241452B2 (en) | 2022-02-08 |
EA202090827A1 (ru) | 2020-06-24 |
CN111093628A (zh) | 2020-05-01 |
US20190314402A1 (en) | 2019-10-17 |
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