MX2020001766A - Composiciones de aminoacidos para el tratamiento de lesion neuronal. - Google Patents
Composiciones de aminoacidos para el tratamiento de lesion neuronal.Info
- Publication number
- MX2020001766A MX2020001766A MX2020001766A MX2020001766A MX2020001766A MX 2020001766 A MX2020001766 A MX 2020001766A MX 2020001766 A MX2020001766 A MX 2020001766A MX 2020001766 A MX2020001766 A MX 2020001766A MX 2020001766 A MX2020001766 A MX 2020001766A
- Authority
- MX
- Mexico
- Prior art keywords
- amino acids
- chain amino
- branched
- treatment
- neuronal injury
- Prior art date
Links
- 208000027418 Wounds and injury Diseases 0.000 title abstract 2
- 150000005693 branched-chain amino acids Chemical class 0.000 title abstract 2
- 230000006378 damage Effects 0.000 title abstract 2
- 208000014674 injury Diseases 0.000 title abstract 2
- 230000001537 neural effect Effects 0.000 title abstract 2
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 abstract 1
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 abstract 1
- 208000030886 Traumatic Brain injury Diseases 0.000 abstract 1
- 229960004308 acetylcysteine Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000009529 traumatic brain injury Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
- A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A61K38/063—Glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/02—Acid
- A23V2250/06—Amino acid
- A23V2250/0626—Isoleucine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/02—Acid
- A23V2250/06—Amino acid
- A23V2250/0628—Leucine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/02—Acid
- A23V2250/06—Amino acid
- A23V2250/0634—N-Acetyl-Cysteine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/02—Acid
- A23V2250/06—Amino acid
- A23V2250/0654—Valine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/30—Other Organic compounds
- A23V2250/306—Creatine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Abstract
Se describen composiciones que comprenden aminoácidos ramificados, N-acetilcisteína y acetil-L-carnitina para usarse en el tratamiento o prevención de lesión neuronal en un sujeto, por ejemplo, un sujeto en riesgo de o que tiene lesión cerebral traumática o accidente cerebrovascular.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762545364P | 2017-08-14 | 2017-08-14 | |
US201862614198P | 2018-01-05 | 2018-01-05 | |
US201862697690P | 2018-07-13 | 2018-07-13 | |
PCT/US2018/046659 WO2019036442A1 (en) | 2017-08-14 | 2018-08-14 | AMINO ACIDS BRANCHED FOR THE TREATMENT OF NEURONAL INJURY |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020001766A true MX2020001766A (es) | 2020-07-29 |
Family
ID=63449701
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020001766A MX2020001766A (es) | 2017-08-14 | 2018-08-14 | Composiciones de aminoacidos para el tratamiento de lesion neuronal. |
Country Status (18)
Country | Link |
---|---|
US (1) | US20190046486A1 (es) |
EP (1) | EP3684350A1 (es) |
JP (2) | JP7370960B2 (es) |
KR (1) | KR20200040276A (es) |
CN (1) | CN111295186A (es) |
AU (1) | AU2018318091A1 (es) |
BR (1) | BR112020002244A2 (es) |
CA (1) | CA3072092A1 (es) |
CL (1) | CL2020000383A1 (es) |
CO (1) | CO2020001627A2 (es) |
IL (1) | IL272336A (es) |
JO (1) | JOP20200035A1 (es) |
MA (1) | MA50155A (es) |
MX (1) | MX2020001766A (es) |
PE (1) | PE20200748A1 (es) |
SG (1) | SG11202001131TA (es) |
TW (1) | TW201919602A (es) |
WO (1) | WO2019036442A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JOP20190146A1 (ar) | 2016-12-19 | 2019-06-18 | Axcella Health Inc | تركيبات حمض أميني وطرق لمعالجة أمراض الكبد |
CN110678172A (zh) | 2017-04-28 | 2020-01-10 | 胺细拉健康公司 | 用于治疗创伤性脑损伤的氨基酸组合物及其使用方法 |
CN111295187A (zh) | 2017-08-14 | 2020-06-16 | 胺细拉健康公司 | 用于治疗肝脏疾病的氨基酸组合物 |
CU20200106A7 (es) | 2018-06-20 | 2021-08-06 | Axcella Health Inc | Composiciones y métodos para el tratamiento de hemoglobinopatías y talasemias |
AR115585A1 (es) | 2018-06-20 | 2021-02-03 | Axcella Health Inc | Composiciones y métodos para el tratamiento de la infiltración de grasa en músculo |
EP3810168A1 (en) | 2018-06-20 | 2021-04-28 | Axcella Health Inc. | Methods of manufacturing amino acid compositions |
EP4192441A1 (en) * | 2020-08-06 | 2023-06-14 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Oleylcysteineamide or derivatives thereof and their use in therapy |
US20220218640A1 (en) * | 2021-01-14 | 2022-07-14 | Rob Dickerman | Amino acid delivery system |
US11931127B1 (en) * | 2021-04-08 | 2024-03-19 | T-Mobile Usa, Inc. | Monitoring users biological indicators using a 5G telecommunication network |
TW202315605A (zh) | 2021-07-26 | 2023-04-16 | 美商胺細拉健康公司 | 用於治療covid—19急性後期後遺症的胺基酸組合物及方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4438144A (en) * | 1980-07-31 | 1984-03-20 | Blackburn George L | Amino acid preparation and therapy for treatment of stress and injury |
US20050107338A1 (en) * | 2003-11-17 | 2005-05-19 | Seidman Michael D. | Nutritional supplement enhancing mitochondrial function |
JP5290744B2 (ja) * | 2005-03-21 | 2013-09-18 | アボット・ラボラトリーズ | 糖耐性を改善するためのアミノ酸組成物 |
CN101693740B (zh) * | 2009-10-16 | 2011-09-07 | 中国人民解放军第四军医大学 | Homer1蛋白及其在治疗或预防脑损伤疾病中的应用 |
JP6099574B2 (ja) * | 2011-02-04 | 2017-03-22 | ハフ イヤ インスティテュート | 外傷性脳損傷を処置する方法 |
WO2012125020A1 (en) * | 2011-03-14 | 2012-09-20 | N.V. Nutricia | Method for treating neurotrauma |
US20130090356A1 (en) * | 2011-06-24 | 2013-04-11 | Jon D. Kaiser | Compositions and methods for treatment of neuropsychological deficits |
CA2799127C (en) * | 2012-12-18 | 2021-05-18 | Matthew Bennett | Compositions and methods for treating traumatic brain injury |
US20160058726A1 (en) * | 2013-04-16 | 2016-03-03 | The Children's Hospital Of Philadelphia | Compositions and methods for the treatment of brain injury |
CN106361738A (zh) * | 2016-08-25 | 2017-02-01 | 南通大学 | 治疗、预防脑白质损伤的医药组合物及其医药用途 |
US20180133185A1 (en) * | 2016-11-11 | 2018-05-17 | The Children's Hospital Of Philadelphia | Compositions and Methods for the Improvement of Memory |
JOP20190147A1 (ar) * | 2016-12-19 | 2019-06-18 | Axcella Health Inc | تركيبات حمض أميني وطرق لمعالجة أمراض واضطرابات العضلات |
JOP20190146A1 (ar) * | 2016-12-19 | 2019-06-18 | Axcella Health Inc | تركيبات حمض أميني وطرق لمعالجة أمراض الكبد |
-
2018
- 2018-08-14 KR KR1020207007011A patent/KR20200040276A/ko not_active Application Discontinuation
- 2018-08-14 CA CA3072092A patent/CA3072092A1/en not_active Abandoned
- 2018-08-14 MA MA050155A patent/MA50155A/fr unknown
- 2018-08-14 JO JOP/2020/0035A patent/JOP20200035A1/ar unknown
- 2018-08-14 EP EP18762716.1A patent/EP3684350A1/en active Pending
- 2018-08-14 SG SG11202001131TA patent/SG11202001131TA/en unknown
- 2018-08-14 US US16/103,200 patent/US20190046486A1/en not_active Abandoned
- 2018-08-14 PE PE2020000251A patent/PE20200748A1/es unknown
- 2018-08-14 WO PCT/US2018/046659 patent/WO2019036442A1/en unknown
- 2018-08-14 AU AU2018318091A patent/AU2018318091A1/en not_active Abandoned
- 2018-08-14 MX MX2020001766A patent/MX2020001766A/es unknown
- 2018-08-14 JP JP2020507989A patent/JP7370960B2/ja active Active
- 2018-08-14 TW TW107128277A patent/TW201919602A/zh unknown
- 2018-08-14 BR BR112020002244-6A patent/BR112020002244A2/pt not_active Application Discontinuation
- 2018-08-14 CN CN201880065642.6A patent/CN111295186A/zh active Pending
-
2020
- 2020-01-29 IL IL272336A patent/IL272336A/en unknown
- 2020-02-13 CO CONC2020/0001627A patent/CO2020001627A2/es unknown
- 2020-02-14 CL CL2020000383A patent/CL2020000383A1/es unknown
-
2023
- 2023-07-07 JP JP2023112589A patent/JP2023145496A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
SG11202001131TA (en) | 2020-03-30 |
BR112020002244A2 (pt) | 2020-08-04 |
JOP20200035A1 (ar) | 2020-02-13 |
US20190046486A1 (en) | 2019-02-14 |
IL272336A (en) | 2020-03-31 |
AU2018318091A1 (en) | 2020-02-13 |
JP2020530843A (ja) | 2020-10-29 |
JP7370960B2 (ja) | 2023-10-30 |
CA3072092A1 (en) | 2019-02-21 |
EP3684350A1 (en) | 2020-07-29 |
JP2023145496A (ja) | 2023-10-11 |
CL2020000383A1 (es) | 2020-08-28 |
WO2019036442A9 (en) | 2020-02-13 |
TW201919602A (zh) | 2019-06-01 |
CN111295186A (zh) | 2020-06-16 |
AU2018318091A8 (en) | 2020-03-12 |
WO2019036442A1 (en) | 2019-02-21 |
PE20200748A1 (es) | 2020-07-24 |
CO2020001627A2 (es) | 2020-06-09 |
KR20200040276A (ko) | 2020-04-17 |
MA50155A (fr) | 2020-07-29 |
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