MX2019012439A - Herramienta de diagnostico para determinar el borramiento del proceso del pie del podocito. - Google Patents

Herramienta de diagnostico para determinar el borramiento del proceso del pie del podocito.

Info

Publication number
MX2019012439A
MX2019012439A MX2019012439A MX2019012439A MX2019012439A MX 2019012439 A MX2019012439 A MX 2019012439A MX 2019012439 A MX2019012439 A MX 2019012439A MX 2019012439 A MX2019012439 A MX 2019012439A MX 2019012439 A MX2019012439 A MX 2019012439A
Authority
MX
Mexico
Prior art keywords
podocyte foot
process effacement
subject
foot process
disease associated
Prior art date
Application number
MX2019012439A
Other languages
English (en)
Inventor
Karlhans Endlich
Nicole Endlich
Florian Siegerist
Original Assignee
Ernst Moritz Arndt Univ Greifswald
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58701404&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2019012439(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ernst Moritz Arndt Univ Greifswald filed Critical Ernst Moritz Arndt Univ Greifswald
Publication of MX2019012439A publication Critical patent/MX2019012439A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

La presente invención se refiere a un método para diagnosticar o pre-diagnosticar una enfermedad asociada con el borramiento del proceso del pie del podocito en un sujeto o para determinar el riesgo de que un sujeto desarrolle una enfermedad asociada con el borramiento del proceso del pie del podocito, el método comprende los pasos de: a) determinar la longitud del diafragma de hendidura (lSD) formado por los procesos del pie del podocito en un área específica A en una muestra de tejido renal del sujeto mediante microscopia óptica de super resolución; b) comparar la longitud del diafragma de hendidura (lSD) formado por los procesos del pie del podocito en un área específica A como se determinó en el paso (a) con la longitud del diafragma de hendidura (lSD) formado por los procesos del pie del podocito en un área específica comparable A en una muestra del tejido renal de un sujeto quien en el momento del muestreo no mostró síntomas clínicos de una enfermedad asociada con el borramiento del proceso del pie del podocito, en donde una desviación indica una enfermedad asociada con el borramiento del proceso del pie del podocito.
MX2019012439A 2017-04-27 2018-04-26 Herramienta de diagnostico para determinar el borramiento del proceso del pie del podocito. MX2019012439A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17168506.8A EP3396380B1 (en) 2017-04-27 2017-04-27 Diagnostic tool to determine podocyte foot process effacement
PCT/EP2018/060779 WO2018197633A1 (en) 2017-04-27 2018-04-26 Diagnostic tool to determine podocyte foot process effacement

Publications (1)

Publication Number Publication Date
MX2019012439A true MX2019012439A (es) 2020-07-14

Family

ID=58701404

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019012439A MX2019012439A (es) 2017-04-27 2018-04-26 Herramienta de diagnostico para determinar el borramiento del proceso del pie del podocito.

Country Status (10)

Country Link
US (1) US11747326B2 (es)
EP (1) EP3396380B1 (es)
JP (1) JP7442083B2 (es)
KR (1) KR102510833B1 (es)
AU (1) AU2018260305A1 (es)
CA (1) CA3061214C (es)
DK (1) DK3396380T3 (es)
ES (1) ES2869302T3 (es)
MX (1) MX2019012439A (es)
WO (1) WO2018197633A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116558929B (zh) * 2023-07-07 2023-09-19 中日友好医院(中日友好临床医学研究所) 一种足细胞免疫荧光染色的方法及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005014849A2 (en) * 2003-07-03 2005-02-17 Euro-Celtique, S.A. Genes associated with responses to neuropathic pain
AU2007230724B2 (en) 2006-03-23 2014-01-30 Amgen Inc. Methods and compositions for making and using polymorphs of cinacalcet
CA2672560A1 (en) * 2006-12-15 2008-06-26 Ruprecht-Karls-Universitaet Heidelberg Methods for treating podocyte-related disorders
WO2010042202A1 (en) * 2008-10-07 2010-04-15 Fibrogen, Inc. Methods for treatment of podocyte injury
WO2010140024A1 (en) * 2009-06-03 2010-12-09 Institut National De La Sante Et De La Recherche Medicale (Inserm) Methods for diagnosing and treating a renal disease in an individual

Also Published As

Publication number Publication date
KR102510833B1 (ko) 2023-03-15
JP7442083B2 (ja) 2024-03-04
AU2018260305A1 (en) 2019-10-31
ES2869302T3 (es) 2021-10-25
EP3396380A1 (en) 2018-10-31
JP2020537739A (ja) 2020-12-24
WO2018197633A1 (en) 2018-11-01
DK3396380T3 (da) 2021-06-21
KR20190139997A (ko) 2019-12-18
EP3396380B1 (en) 2021-03-17
US11747326B2 (en) 2023-09-05
CA3061214C (en) 2023-08-01
CA3061214A1 (en) 2018-11-01
US20200049698A1 (en) 2020-02-13

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