MX2019010289A - Composicion en emulsion acida que contiene anestesico local. - Google Patents

Composicion en emulsion acida que contiene anestesico local.

Info

Publication number
MX2019010289A
MX2019010289A MX2019010289A MX2019010289A MX2019010289A MX 2019010289 A MX2019010289 A MX 2019010289A MX 2019010289 A MX2019010289 A MX 2019010289A MX 2019010289 A MX2019010289 A MX 2019010289A MX 2019010289 A MX2019010289 A MX 2019010289A
Authority
MX
Mexico
Prior art keywords
local anesthetic
anesthetic agent
composition containing
emulsion composition
acidic emulsion
Prior art date
Application number
MX2019010289A
Other languages
English (en)
Inventor
Okamoto Kazuki
MASUI Kuniharu
Nomura Mai
CHIDA Yuichiro
Original Assignee
Maruishi Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maruishi Pharma filed Critical Maruishi Pharma
Publication of MX2019010289A publication Critical patent/MX2019010289A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/25—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids with polyoxyalkylated alcohols, e.g. esters of polyethylene glycol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Un objeto de la presente invención es proporcionar una composición que contiene anestésico local caracterizada por (1) ejercer un efecto medicinal inmediato y duradero sin liberación sostenida después de la administración, y/o (2) tener estabilidad de almacenamiento. La presente invención proporciona una composición en emulsión ácida que comprende un anestésico local y un glicérido en el que un(os) ácido(s) graso(s) que tiene(n) de 6 a 12 átomos de carbono está/están unido(s) a glicerina a través de un enlace(s)de éster.
MX2019010289A 2017-03-06 2018-03-06 Composicion en emulsion acida que contiene anestesico local. MX2019010289A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017042253 2017-03-06
PCT/JP2018/008572 WO2018164121A1 (ja) 2017-03-06 2018-03-06 局所麻酔薬含有酸性エマルション組成物

Publications (1)

Publication Number Publication Date
MX2019010289A true MX2019010289A (es) 2019-10-21

Family

ID=63448429

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019010289A MX2019010289A (es) 2017-03-06 2018-03-06 Composicion en emulsion acida que contiene anestesico local.

Country Status (10)

Country Link
US (1) US20200030305A1 (es)
EP (1) EP3593801A4 (es)
JP (1) JPWO2018164121A1 (es)
KR (1) KR20190121752A (es)
CN (1) CN110402142A (es)
BR (1) BR112019018105A2 (es)
CA (1) CA3055277A1 (es)
MX (1) MX2019010289A (es)
RU (1) RU2019131370A (es)
WO (1) WO2018164121A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021173624A1 (en) * 2020-02-25 2021-09-02 The University Of North Carolina At Chapel Hill Eutectic based anesthetic compositions and applications thereof
CN115414324A (zh) * 2021-05-31 2022-12-02 中国科学院过程工程研究所 一种载局部麻醉药的乳剂及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5212277A (en) 1975-07-18 1977-01-29 Furukawa Electric Co Ltd Process for producing crosslinked polyolefin foam
JP3701693B2 (ja) 1993-12-28 2005-10-05 日本製薬株式会社 鎮痛薬含有注射用徐放性脂肪乳剤
EP0770387B1 (en) 1995-10-28 1999-08-11 B. Braun Melsungen Ag Pharmaceutical composition containing a local anesthetic and/or centrally acting analgesic
ES2343767T3 (es) 1997-09-18 2010-08-09 Pacira Pharmaceuticals, Inc. Composiciones anestesicas liposomicas de liberacion sostenida.
JP2001151668A (ja) * 1999-11-22 2001-06-05 Jcr Pharmaceuticals Co Ltd 経皮吸収製剤
WO2004052354A1 (ja) * 2002-12-06 2004-06-24 Otsuka Pharmaceutical Factory, Inc. プロポフォール含有脂肪乳剤
CN101904814A (zh) * 2009-06-04 2010-12-08 上海恒瑞医药有限公司 制备载药乳剂的方法
FR2983731B1 (fr) * 2011-12-07 2014-04-25 Univ Paris Descartes Emulsions topiques a base de melanges eutectiques d'anesthesiques locaux et d'acide gras
JPWO2015132985A1 (ja) 2014-03-03 2017-04-06 丸石製薬株式会社 セボフルラン含有エマルション組成物
CN107789628B (zh) * 2016-12-29 2021-07-23 天津键凯科技有限公司 一种聚乙二醇和局部麻醉药的结合物在非麻醉镇痛中的应用

Also Published As

Publication number Publication date
EP3593801A1 (en) 2020-01-15
CN110402142A (zh) 2019-11-01
CA3055277A1 (en) 2018-09-13
RU2019131370A3 (es) 2021-06-24
US20200030305A1 (en) 2020-01-30
EP3593801A4 (en) 2021-01-13
RU2019131370A (ru) 2021-04-07
BR112019018105A2 (pt) 2020-03-24
KR20190121752A (ko) 2019-10-28
WO2018164121A1 (ja) 2018-09-13
JPWO2018164121A1 (ja) 2020-01-16

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