MX2019007574A - Metodos de tratamiento de sindrome de intestino irritable con formulaciones modificadas o de liberacion retardada de linaclotida. - Google Patents
Metodos de tratamiento de sindrome de intestino irritable con formulaciones modificadas o de liberacion retardada de linaclotida.Info
- Publication number
- MX2019007574A MX2019007574A MX2019007574A MX2019007574A MX2019007574A MX 2019007574 A MX2019007574 A MX 2019007574A MX 2019007574 A MX2019007574 A MX 2019007574A MX 2019007574 A MX2019007574 A MX 2019007574A MX 2019007574 A MX2019007574 A MX 2019007574A
- Authority
- MX
- Mexico
- Prior art keywords
- linaclotide
- delayed release
- modified
- methods
- release formulations
- Prior art date
Links
- 230000003111 delayed effect Effects 0.000 title abstract 2
- KXGCNMMJRFDFNR-WDRJZQOASA-N linaclotide Chemical compound C([C@H](NC(=O)[C@@H]1CSSC[C@H]2C(=O)N[C@H]3CSSC[C@H](N)C(=O)N[C@H](C(N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N2)=O)CSSC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC3=O)C(=O)N[C@H](C(NCC(=O)N1)=O)[C@H](O)C)C(O)=O)C1=CC=C(O)C=C1 KXGCNMMJRFDFNR-WDRJZQOASA-N 0.000 title abstract 2
- 229960000812 linaclotide Drugs 0.000 title abstract 2
- 108010024409 linaclotide Proteins 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- 208000002551 irritable bowel syndrome Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662437566P | 2016-12-21 | 2016-12-21 | |
| PCT/US2017/067814 WO2018119191A1 (en) | 2016-12-21 | 2017-12-21 | Methods of treating irritable bowel syndrome with modified or delayed release formulations of linaclotide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019007574A true MX2019007574A (es) | 2019-09-04 |
Family
ID=61022424
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019007574A MX2019007574A (es) | 2016-12-21 | 2017-12-21 | Metodos de tratamiento de sindrome de intestino irritable con formulaciones modificadas o de liberacion retardada de linaclotida. |
| MX2023008839A MX2023008839A (es) | 2016-12-21 | 2019-06-21 | Composicion de liberacion tardia de linaclotida para uso en el tratamiento de trastornos gastrointestinales. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023008839A MX2023008839A (es) | 2016-12-21 | 2019-06-21 | Composicion de liberacion tardia de linaclotida para uso en el tratamiento de trastornos gastrointestinales. |
Country Status (10)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3140528A1 (en) * | 2019-06-10 | 2020-12-17 | Wilmin Bartolini | Treatment of abdominal pain associated with diarrhea-predominant irritable bowel syndrome |
| KR20240111797A (ko) * | 2021-11-29 | 2024-07-17 | 아이언우드 파마슈티컬스, 인코포레이티드 | 내장 통증의 치료를 위한 제약 조성물 |
| WO2023196821A2 (en) * | 2022-04-04 | 2023-10-12 | Thomas Jefferson University | Targeting neuropod cell gucy2c to control visceral pain and appetite |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7371727B2 (en) | 2003-01-28 | 2008-05-13 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US7304036B2 (en) | 2003-01-28 | 2007-12-04 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| PL2328601T3 (pl) | 2008-08-15 | 2020-07-13 | Ironwood Pharmaceuticals, Inc. | Formulacje zawierające linaklotyd do podawania doustnego |
| EP2464373A1 (en) * | 2009-08-13 | 2012-06-20 | Ironwood Pharmaceuticals, Inc. | Method for modulating the pharmacodynamic effect of orally administered guanylate cyclase receptor agonists |
| PL2536742T3 (pl) | 2010-02-17 | 2017-11-30 | Ironwood Pharmaceuticals, Inc. | Leczenie zaburzeń żołądkowo-jelitowych |
| ES2763404T3 (es) * | 2010-08-11 | 2020-05-28 | Ironwood Pharmaceuticals Inc | Formulaciones estables de linaclotida |
| US9708371B2 (en) * | 2011-08-17 | 2017-07-18 | Ironwood Pharmaceuticals, Inc. | Treatments for gastrointestinal disorders |
| BR112015016917B1 (pt) * | 2013-01-15 | 2022-08-30 | Ironwood Pharmaceuticals, Inc | Forma de dosagem oral de retenção gástrica, e, uso de um sequestrante de ácido biliar |
| UA119335C2 (uk) * | 2013-12-11 | 2019-06-10 | Айронвуд Фармасьютикалз, Інк. | Композиції лінаклотиду з затриманим вивільненням |
| WO2016197042A1 (en) * | 2015-06-05 | 2016-12-08 | Ironwood Pharmaceuticals, Inc. | Modified or targeted release formulations of linaclotide |
-
2017
- 2017-12-21 BR BR112019012689-9A patent/BR112019012689A2/pt unknown
- 2017-12-21 MA MA047112A patent/MA47112A/fr unknown
- 2017-12-21 JP JP2019533167A patent/JP2020512292A/ja active Pending
- 2017-12-21 MX MX2019007574A patent/MX2019007574A/es unknown
- 2017-12-21 WO PCT/US2017/067814 patent/WO2018119191A1/en not_active Application Discontinuation
- 2017-12-21 CN CN201780087073.0A patent/CN110475564A/zh active Pending
- 2017-12-21 AU AU2017379082A patent/AU2017379082A1/en not_active Abandoned
- 2017-12-21 EP EP17833050.2A patent/EP3558337A1/en not_active Withdrawn
- 2017-12-21 EA EA201991531A patent/EA201991531A1/ru unknown
- 2017-12-21 CA CA3048195A patent/CA3048195A1/en active Pending
-
2019
- 2019-06-21 MX MX2023008839A patent/MX2023008839A/es unknown
-
2022
- 2022-04-27 JP JP2022073214A patent/JP2022093472A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA3048195A1 (en) | 2018-06-28 |
| BR112019012689A2 (pt) | 2019-11-19 |
| JP2022093472A (ja) | 2022-06-23 |
| EA201991531A1 (ru) | 2019-11-29 |
| WO2018119191A9 (en) | 2018-10-18 |
| EP3558337A1 (en) | 2019-10-30 |
| MA47112A (fr) | 2019-10-30 |
| JP2020512292A (ja) | 2020-04-23 |
| MX2023008839A (es) | 2023-08-14 |
| WO2018119191A1 (en) | 2018-06-28 |
| CN110475564A (zh) | 2019-11-19 |
| AU2017379082A1 (en) | 2019-07-04 |
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