MX2019002924A - Composiciones purificadas de oligosacaridos de leche humana. - Google Patents

Composiciones purificadas de oligosacaridos de leche humana.

Info

Publication number
MX2019002924A
MX2019002924A MX2019002924A MX2019002924A MX2019002924A MX 2019002924 A MX2019002924 A MX 2019002924A MX 2019002924 A MX2019002924 A MX 2019002924A MX 2019002924 A MX2019002924 A MX 2019002924A MX 2019002924 A MX2019002924 A MX 2019002924A
Authority
MX
Mexico
Prior art keywords
human milk
purified human
milk oligosaccharides
compositions
oligosaccharides compositions
Prior art date
Application number
MX2019002924A
Other languages
English (en)
Spanish (es)
Inventor
Sun Adam
D Huynh Tin
Le Bouedec Annabelle
Thu Tran Kim
Original Assignee
Prolacta Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prolacta Bioscience Inc filed Critical Prolacta Bioscience Inc
Publication of MX2019002924A publication Critical patent/MX2019002924A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • C07H1/06Separation; Purification
    • C07H1/08Separation; Purification from natural products
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/14Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/142Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/14Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/142Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
    • A23C9/1422Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by ultrafiltration, microfiltration or diafiltration of milk, e.g. for separating protein and lactose; Treatment of the UF permeate
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/12Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/1203Addition of, or treatment with, enzymes or microorganisms other than lactobacteriaceae
    • A23C9/1206Lactose hydrolysing enzymes, e.g. lactase, beta-galactosidase
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/20Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/20Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • A23C9/206Colostrum; Human milk
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02Monosaccharides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04Disaccharides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/14Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01108Lactase (3.2.1.108)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/324Foods, ingredients or supplements having a functional effect on health having an effect on the immune system
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00Food ingredients
    • A23V2250/28Oligosaccharides
    • A23V2250/282Oligosaccharides, digestible
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20Milk; Whey; Colostrum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Water Supply & Treatment (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Dairy Products (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
MX2019002924A 2016-09-19 2017-09-19 Composiciones purificadas de oligosacaridos de leche humana. MX2019002924A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662396779P 2016-09-19 2016-09-19
PCT/US2017/052332 WO2018053535A1 (en) 2016-09-19 2017-09-19 Purified human milk oligosaccharides compositions

Publications (1)

Publication Number Publication Date
MX2019002924A true MX2019002924A (es) 2019-10-14

Family

ID=61620164

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019002924A MX2019002924A (es) 2016-09-19 2017-09-19 Composiciones purificadas de oligosacaridos de leche humana.

Country Status (12)

Country Link
US (2) US20200054035A1 (https=)
EP (1) EP3515195A4 (https=)
JP (3) JP7143286B2 (https=)
KR (2) KR102821643B1 (https=)
CN (1) CN109843073A (https=)
AU (3) AU2017326654C1 (https=)
BR (1) BR112019005329A2 (https=)
CA (1) CA3037203A1 (https=)
IL (2) IL290057B2 (https=)
MX (1) MX2019002924A (https=)
RU (1) RU2754463C2 (https=)
WO (1) WO2018053535A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202126317A (zh) 2019-09-24 2021-07-16 美商普拉塔生技公司 用於治療發炎和免疫疾病之組成物和方法
JP2022550680A (ja) * 2019-10-01 2022-12-05 グリコム・アクティーゼルスカブ 発酵ブロスからの中性オリゴ糖の分離
WO2022148549A1 (en) 2020-01-14 2022-07-14 Babylat Gmbh Apparatus and method for obtaining protein-enriched fractions from breast milk
WO2021250191A1 (en) * 2020-06-12 2021-12-16 Basf Se Improved demineralization of fermentation broths and purification of fine chemicals such as oligosaccharides
CA3188645A1 (en) 2020-08-14 2022-02-17 Prolacta Bioscience, Inc. Human milk oligosaccharide compositions for use with bacteriotherapies
EP4277634A1 (en) 2021-01-12 2023-11-22 Prolacta Bioscience, Inc. Synbiotic treatment regimens
JP2024504983A (ja) 2021-01-22 2024-02-02 プロラクタ バイオサイエンス,インコーポレイテッド ヒト乳局所製剤
EP4042875B1 (en) * 2021-02-15 2025-07-30 Rakesh Kumar Aggarwal A human milk fortifier
CN113899827A (zh) * 2021-09-29 2022-01-07 中国科学院合肥物质科学研究院 一种3’-唾液酸乳糖的检测方法及其应用
US20250297294A1 (en) * 2021-12-23 2025-09-25 Amyris, Inc. Compositions and methods for improved production of human milk oligosaccharides
EP4230050A4 (en) * 2021-12-29 2024-06-12 Beijing Sanyuan Foods Co., Ltd. METHOD FOR PREPARING MILK OLIGOSACCHARIDE, OLIGOSACCHARIDE POWDER PREPARED USING THE SAME, AND FOODS
WO2024130119A2 (en) 2022-12-16 2024-06-20 Prolacta Bioscience, Inc. Synbiotic compositions for short chain fatty acid production

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2459619B1 (fr) * 1979-06-26 1983-07-29 Agronomique Inst Nat Rech Procede pour l'obtention a partir de lactoserum, d'un produit enrichi en alpha-lactalbumine et applications dudit procede
JPH0631286B2 (ja) * 1987-12-24 1994-04-27 雪印乳業株式会社 シアル酸類含有組成物の製造法
US6045854A (en) * 1997-03-31 2000-04-04 Abbott Laboraties Nutritional formulations containing oligosaccharides
US6288222B1 (en) * 2000-02-16 2001-09-11 Neose Technologies, Inc. Method of filtration of a dairy stream
DK1733730T3 (da) * 2003-10-24 2008-10-13 Nutricia Nv Immunmodulerende oligosaccharider
BRPI0707620A2 (pt) * 2006-02-10 2011-05-10 Nestec Sa mistura de oligossacarÍdeo
US7531632B2 (en) 2006-02-16 2009-05-12 Gtc Biotherapeutics, Inc. Clarification of transgenic milk using depth filtration
JP2012510476A (ja) 2008-12-02 2012-05-10 プロラクタ バイオサイエンス,インコーポレイテッド ヒト乳透過組成物ならびにその製造および使用方法
NZ595174A (en) * 2009-03-13 2013-04-26 Univ California Prebiotic galacto oligosaccharides used to stimulate growth or colonisation of beneficial bifidobacterium bacteria in gut
TWI527522B (zh) * 2010-08-13 2016-04-01 愛之味股份有限公司 製備富含半乳寡醣及低乳糖之易吸收乳製品之方法及以該方法製備之機能性乳製品
ES2708924T3 (es) * 2010-12-31 2019-04-12 Abbott Lab Procedimientos de uso de oligosacáridos de la leche humana para mejorar la salud respiratoria de las vías respiratorias
MY197622A (en) * 2010-12-31 2023-06-28 Abbott Lab Methods for decreasing the incidence of necrotizing enterocolitis in infants, toddlers, or children using human milk oligosaccharides
US20140087404A1 (en) 2011-03-14 2014-03-27 Godo Shusei Co., Ltd. Method for assaying arylsulfatase activity
EP2526784A1 (en) 2011-05-24 2012-11-28 Nestec S.A. Milk oligosaccharide-galactooligosaccharide composition for infant formula containing the soluble oligosaccharide fraction present in milk, and having a low level of monosaccharides, and a process to produce the composition
NL2007931C2 (en) * 2011-12-07 2013-06-10 Friesland Brands Bv Methods for providing sialylated oligosaccharides and products obtainable thereby.
PT2797436T (pt) * 2012-01-01 2020-10-20 Botanical Water Tech Ip Ltd Métodos para preparação de bebidas à base de plantas
EP2620506A1 (en) * 2012-01-25 2013-07-31 Arla Foods Amba Method of producing a galacto-oligosaccharide-containing composition
KR101379450B1 (ko) * 2013-07-23 2014-03-31 장세현 모유 성분인 갈락토실락토스가 강화된 갈락토올리고당의 제조 방법
PL2845905T3 (pl) * 2013-09-10 2021-09-27 Chr. Hansen HMO GmbH Wytwarzanie oligosacharydów
EP3212197A4 (en) * 2014-10-29 2018-07-11 Glycom A/S Synthetic composition and method for treating irritable bowel syndrome
BR112017011607A2 (pt) 2014-12-05 2018-01-09 Godo Shusei Kk solução de lactase e produto lácteo usando a mesma

Also Published As

Publication number Publication date
AU2017326654B2 (en) 2022-01-20
IL265373A (en) 2019-05-30
AU2017326654C1 (en) 2022-07-21
RU2019110171A (ru) 2020-10-19
AU2022202598A1 (en) 2022-05-12
KR20230130667A (ko) 2023-09-12
WO2018053535A1 (en) 2018-03-22
KR102593408B1 (ko) 2023-10-25
IL265373B (en) 2022-02-01
RU2754463C2 (ru) 2021-09-02
CA3037203A1 (en) 2018-03-22
EP3515195A1 (en) 2019-07-31
US20200054035A1 (en) 2020-02-20
IL290057A (en) 2022-03-01
JP2019528740A (ja) 2019-10-17
JP2023002512A (ja) 2023-01-10
KR102821643B1 (ko) 2025-06-18
KR20190054097A (ko) 2019-05-21
AU2022202598B2 (en) 2024-04-04
RU2019110171A3 (https=) 2021-02-11
BR112019005329A2 (pt) 2019-06-18
IL290057B1 (en) 2023-05-01
JP7143286B2 (ja) 2022-09-28
AU2024204350A1 (en) 2024-07-11
US20250089732A1 (en) 2025-03-20
JP2024150451A (ja) 2024-10-23
AU2017326654A1 (en) 2019-03-14
CN109843073A (zh) 2019-06-04
IL290057B2 (en) 2023-09-01
EP3515195A4 (en) 2020-05-27
JP7510978B2 (ja) 2024-07-04

Similar Documents

Publication Publication Date Title
MX2019002924A (es) Composiciones purificadas de oligosacaridos de leche humana.
EP3565892A4 (en) Cell-free production of sugars
MA42038A (fr) Dérivés de cyclohexane à substitution amido
MX390064B (es) Formas cristalinas de mononucleotido de beta-nicotinamida.
EP3402567A4 (en) IMPLANTABLE RELAY MODULE
EP3490490A4 (en) TEETH ALIGNMENT SYSTEM
BR112019004785A2 (pt) variantes de alfa-glicosidase ácida e usos das mesmas
MX2017015579A (es) Formas de dosificacion solidas de palbociclib.
BR112017009374A2 (pt) ?composições de ramnolipídeo de baixa viscosidade concentradas?
EP3606559C0 (en) BIOORTHOGONAL COMPOSITIONS
MX2017002469A (es) Composiciones de matrices extracelulares.
BR112019004783A2 (pt) variantes de alfa-glicosidase ácida e usos das mesmas
MX2018007390A (es) Composiciones que comprenden acido 15-hidroxi eicosapentaenoico (15-hepe) y metodos de uso del mismo.
PT4129270T (pt) Formulações de aminoácidos administradas por via oral de libertação modificada
CR20170008A (es) Compuestos de [1,2,4] triazol e imidazol sustituidos
DK3244878T3 (da) Faste orale sammensætningsformer
EP3549590A4 (en) CELL PREPARATION
EP3554472A4 (en) PETROLATUM SUBSTITUTION PREPARATION
EP3998092C0 (en) ANTIBIOTIC FORMULATIONS FOR LOWER BAR PAIN
UY36500A (es) Composiciones del inhibidor de la nitrificación y métodos de preparación de las mismas
MX2016012784A (es) Composiciones farmaceuticas solidas que comprenden derivados de biopterina y usos de tales composiciones.
MX2017005578A (es) Métodos de administración de composiciones de amantadina.
BR112018012943A2 (pt) forma cristalina de gencitabina
UY35997A (es) Derivados de isoquinoleína, su procedimiento de preparación y las composiciones farmacéuticas que los contienen
DK3706724T3 (da) Orale rifamycin-sv-sammensætninger