AU2017326654C1 - Purified human milk oligosaccharides compositions - Google Patents

Purified human milk oligosaccharides compositions Download PDF

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Publication number
AU2017326654C1
AU2017326654C1 AU2017326654A AU2017326654A AU2017326654C1 AU 2017326654 C1 AU2017326654 C1 AU 2017326654C1 AU 2017326654 A AU2017326654 A AU 2017326654A AU 2017326654 A AU2017326654 A AU 2017326654A AU 2017326654 C1 AU2017326654 C1 AU 2017326654C1
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AU
Australia
Prior art keywords
permeate
hmo
lactase
human milk
purified
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Active
Application number
AU2017326654A
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English (en)
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AU2017326654B2 (en
AU2017326654A1 (en
Inventor
Tin D. HUYNH
Annabelle LE BOUEDEC
Adam SUN
Kim Thu TRAN
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Prolacta Bioscience Inc
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Prolacta Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Prolacta Bioscience Inc filed Critical Prolacta Bioscience Inc
Publication of AU2017326654A1 publication Critical patent/AU2017326654A1/en
Publication of AU2017326654B2 publication Critical patent/AU2017326654B2/en
Priority to AU2022202598A priority Critical patent/AU2022202598B2/en
Application granted granted Critical
Publication of AU2017326654C1 publication Critical patent/AU2017326654C1/en
Priority to AU2024204350A priority patent/AU2024204350A1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
    • A23C9/1422—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by ultrafiltration, microfiltration or diafiltration of milk, e.g. for separating protein and lactose; Treatment of the UF permeate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/1203—Addition of, or treatment with, enzymes or microorganisms other than lactobacteriaceae
    • A23C9/1206—Lactose hydrolysing enzymes, e.g. lactase, beta-galactosidase
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • A23C9/206—Colostrum; Human milk
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01108—Lactase (3.2.1.108)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/324—Foods, ingredients or supplements having a functional effect on health having an effect on the immune system
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/28—Oligosaccharides
    • A23V2250/282—Oligosaccharides, digestible
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Water Supply & Treatment (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Dairy Products (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AU2017326654A 2016-09-19 2017-09-19 Purified human milk oligosaccharides compositions Active AU2017326654C1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2022202598A AU2022202598B2 (en) 2016-09-19 2022-04-20 Purified human milk oligosaccharides compositions
AU2024204350A AU2024204350A1 (en) 2016-09-19 2024-06-25 Purified human milk oligosaccharides compositions

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662396779P 2016-09-19 2016-09-19
US62/396,779 2016-09-19
PCT/US2017/052332 WO2018053535A1 (en) 2016-09-19 2017-09-19 Purified human milk oligosaccharides compositions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2022202598A Division AU2022202598B2 (en) 2016-09-19 2022-04-20 Purified human milk oligosaccharides compositions

Publications (3)

Publication Number Publication Date
AU2017326654A1 AU2017326654A1 (en) 2019-03-14
AU2017326654B2 AU2017326654B2 (en) 2022-01-20
AU2017326654C1 true AU2017326654C1 (en) 2022-07-21

Family

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Application Number Title Priority Date Filing Date
AU2017326654A Active AU2017326654C1 (en) 2016-09-19 2017-09-19 Purified human milk oligosaccharides compositions
AU2022202598A Active AU2022202598B2 (en) 2016-09-19 2022-04-20 Purified human milk oligosaccharides compositions
AU2024204350A Pending AU2024204350A1 (en) 2016-09-19 2024-06-25 Purified human milk oligosaccharides compositions

Family Applications After (2)

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AU2022202598A Active AU2022202598B2 (en) 2016-09-19 2022-04-20 Purified human milk oligosaccharides compositions
AU2024204350A Pending AU2024204350A1 (en) 2016-09-19 2024-06-25 Purified human milk oligosaccharides compositions

Country Status (12)

Country Link
US (2) US20200054035A1 (https=)
EP (1) EP3515195A4 (https=)
JP (3) JP7143286B2 (https=)
KR (2) KR102821643B1 (https=)
CN (1) CN109843073A (https=)
AU (3) AU2017326654C1 (https=)
BR (1) BR112019005329A2 (https=)
CA (1) CA3037203A1 (https=)
IL (2) IL290057B2 (https=)
MX (1) MX2019002924A (https=)
RU (1) RU2754463C2 (https=)
WO (1) WO2018053535A1 (https=)

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TW202126317A (zh) 2019-09-24 2021-07-16 美商普拉塔生技公司 用於治療發炎和免疫疾病之組成物和方法
JP2022550680A (ja) * 2019-10-01 2022-12-05 グリコム・アクティーゼルスカブ 発酵ブロスからの中性オリゴ糖の分離
WO2022148549A1 (en) 2020-01-14 2022-07-14 Babylat Gmbh Apparatus and method for obtaining protein-enriched fractions from breast milk
WO2021250191A1 (en) * 2020-06-12 2021-12-16 Basf Se Improved demineralization of fermentation broths and purification of fine chemicals such as oligosaccharides
CA3188645A1 (en) 2020-08-14 2022-02-17 Prolacta Bioscience, Inc. Human milk oligosaccharide compositions for use with bacteriotherapies
EP4277634A1 (en) 2021-01-12 2023-11-22 Prolacta Bioscience, Inc. Synbiotic treatment regimens
JP2024504983A (ja) 2021-01-22 2024-02-02 プロラクタ バイオサイエンス，インコーポレイテッド ヒト乳局所製剤
EP4042875B1 (en) * 2021-02-15 2025-07-30 Rakesh Kumar Aggarwal A human milk fortifier
CN113899827A (zh) * 2021-09-29 2022-01-07 中国科学院合肥物质科学研究院 一种3’-唾液酸乳糖的检测方法及其应用
US20250297294A1 (en) * 2021-12-23 2025-09-25 Amyris, Inc. Compositions and methods for improved production of human milk oligosaccharides
EP4230050A4 (en) * 2021-12-29 2024-06-12 Beijing Sanyuan Foods Co., Ltd. METHOD FOR PREPARING MILK OLIGOSACCHARIDE, OLIGOSACCHARIDE POWDER PREPARED USING THE SAME, AND FOODS
WO2024130119A2 (en) 2022-12-16 2024-06-20 Prolacta Bioscience, Inc. Synbiotic compositions for short chain fatty acid production

Citations (1)

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US20130059815A1 (en) * 2008-12-02 2013-03-07 Prolacta Bioscience, Inc. Nutritional compositions containing human milk oligosaccharides and methods for using the same

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Also Published As

Publication number Publication date
AU2017326654B2 (en) 2022-01-20
IL265373A (en) 2019-05-30
RU2019110171A (ru) 2020-10-19
AU2022202598A1 (en) 2022-05-12
KR20230130667A (ko) 2023-09-12
WO2018053535A1 (en) 2018-03-22
KR102593408B1 (ko) 2023-10-25
IL265373B (en) 2022-02-01
RU2754463C2 (ru) 2021-09-02
CA3037203A1 (en) 2018-03-22
EP3515195A1 (en) 2019-07-31
US20200054035A1 (en) 2020-02-20
MX2019002924A (es) 2019-10-14
IL290057A (en) 2022-03-01
JP2019528740A (ja) 2019-10-17
JP2023002512A (ja) 2023-01-10
KR102821643B1 (ko) 2025-06-18
KR20190054097A (ko) 2019-05-21
AU2022202598B2 (en) 2024-04-04
RU2019110171A3 (https=) 2021-02-11
BR112019005329A2 (pt) 2019-06-18
IL290057B1 (en) 2023-05-01
JP7143286B2 (ja) 2022-09-28
AU2024204350A1 (en) 2024-07-11
US20250089732A1 (en) 2025-03-20
JP2024150451A (ja) 2024-10-23
AU2017326654A1 (en) 2019-03-14
CN109843073A (zh) 2019-06-04
IL290057B2 (en) 2023-09-01
EP3515195A4 (en) 2020-05-27
JP7510978B2 (ja) 2024-07-04

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT FILED 09 JUN 2022