MX2018012511A - Combinaciones para el tratamiento de neoplasias usando localizacion de celulas quiescentes e inhibidores de egfr. - Google Patents

Combinaciones para el tratamiento de neoplasias usando localizacion de celulas quiescentes e inhibidores de egfr.

Info

Publication number
MX2018012511A
MX2018012511A MX2018012511A MX2018012511A MX2018012511A MX 2018012511 A MX2018012511 A MX 2018012511A MX 2018012511 A MX2018012511 A MX 2018012511A MX 2018012511 A MX2018012511 A MX 2018012511A MX 2018012511 A MX2018012511 A MX 2018012511A
Authority
MX
Mexico
Prior art keywords
treatment
neoplasms
combinations
cell targeting
egfr inhibitors
Prior art date
Application number
MX2018012511A
Other languages
English (en)
Spanish (es)
Inventor
Vilenchik Maria
Frid Michael
Kuznetsova Alexandra
Gankin Yuriy
Duey Marc
Original Assignee
Felicitex Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Felicitex Therapeutics Inc filed Critical Felicitex Therapeutics Inc
Publication of MX2018012511A publication Critical patent/MX2018012511A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2018012511A 2016-04-15 2017-04-14 Combinaciones para el tratamiento de neoplasias usando localizacion de celulas quiescentes e inhibidores de egfr. MX2018012511A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662323537P 2016-04-15 2016-04-15
PCT/US2017/027719 WO2017181075A1 (en) 2016-04-15 2017-04-14 Combinations for the treatment of neoplasms using quiescent cell targeting and egfr inhibitors

Publications (1)

Publication Number Publication Date
MX2018012511A true MX2018012511A (es) 2019-07-08

Family

ID=60039950

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2018012511A MX2018012511A (es) 2016-04-15 2017-04-14 Combinaciones para el tratamiento de neoplasias usando localizacion de celulas quiescentes e inhibidores de egfr.
MX2023000549A MX2023000549A (es) 2016-04-15 2018-10-12 Combinaciones para el tratamiento de neoplasias usando localizacion de celulas quiescentes e inhibidores de egfr.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2023000549A MX2023000549A (es) 2016-04-15 2018-10-12 Combinaciones para el tratamiento de neoplasias usando localizacion de celulas quiescentes e inhibidores de egfr.

Country Status (11)

Country Link
US (3) US10322128B2 (OSRAM)
EP (1) EP3442505A4 (OSRAM)
JP (2) JP7123806B2 (OSRAM)
KR (2) KR20230020565A (OSRAM)
CN (1) CN109562176A (OSRAM)
AU (2) AU2017248762A1 (OSRAM)
BR (1) BR112018071031A2 (OSRAM)
CA (1) CA3021021A1 (OSRAM)
IL (2) IL262323B (OSRAM)
MX (2) MX2018012511A (OSRAM)
WO (1) WO2017181075A1 (OSRAM)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017120349A1 (en) * 2016-01-05 2017-07-13 The Trustees Of Columbia University In The City Of New York Compositions and methods for regulating activity of inhibitor of dna binding-2 (id2) protein
CN109562176A (zh) 2016-04-15 2019-04-02 费利克斯疗法公司 使用静止细胞靶向和egfr抑制剂的用于治疗肿瘤的组合
BR112018071023A2 (pt) 2016-04-15 2019-02-05 Felicitex Therapeutics Inc combinações para o tratamento de neoplasmas utilizando o direcionamento de células inativas e inibidores da mitose
CA3168211A1 (en) 2019-01-18 2020-07-23 Voronoi Co., Ltd. Pyrrolopyridine derivative and use thereof for preventing or treating protein kinase related disease
KR20200135743A (ko) * 2019-05-22 2020-12-03 보로노이 주식회사 암의 예방 및/또는 치료를 위한 피롤로-피리딘 유도체 화합물의 신규 용도
KR20220081631A (ko) 2020-12-09 2022-06-16 보로노이 주식회사 염증성 질환의 예방 및/또는 치료를 위한 피롤로-피리딘 유도체 화합물의 신규 용도
WO2022265950A1 (en) * 2021-06-15 2022-12-22 Genentech, Inc. Egfr inhibitor and perk activator in combination therapy and their use for treating cancer
CA3242316A1 (en) 2021-12-30 2023-07-06 Biomea Fusion, Inc. Pyrazine compounds as inhibitors of flt3
CN115947673B (zh) * 2022-12-19 2024-03-15 湖南岳靶生物医药有限公司 一种化疗药物增敏剂、组合物及其应用
CN116212030A (zh) * 2023-03-03 2023-06-06 河南真实生物科技有限公司 包含阿兹夫定的抗肿瘤药物组合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2560004A1 (de) * 2011-08-19 2013-02-20 DST Diagnostische Systeme & Technologien GmbH Neues PoC-Testsystem und Verfahren
PL2744797T3 (pl) * 2011-08-19 2016-01-29 Diaxonhit Inhibitory dyrk1 i ich zastosowanie
US20150292032A1 (en) * 2012-10-10 2015-10-15 Felicitex Therapeutics, Inc. Treatment of cancer by targeting quiescent cancer cells
CA2854542A1 (en) * 2013-06-18 2014-12-18 4Sc Discovery Gmbh Method of inhibiting dyrk1b
PE20170127A1 (es) 2014-03-20 2017-03-30 Samumed Llc Indazol-3-carboxamidas 5-sustituidas y preparacion y uso de las mismas
WO2016038610A1 (en) 2014-09-08 2016-03-17 Yeda Research And Development Co. Ltd. Compositions and methods for treating cancer resistant to a tyrosine kinase inhibitor (tki)
US20170304313A1 (en) * 2014-10-06 2017-10-26 Novartis Ag Therapeutic Combination For The Treatment Of Cancer
CN108135871B (zh) * 2015-07-23 2022-11-04 博蔚医药生物科技股份有限公司 阻断疾病的泛素化-蛋白酶体系统的胺萘醌化合物及医药组合物
CN109562176A (zh) 2016-04-15 2019-04-02 费利克斯疗法公司 使用静止细胞靶向和egfr抑制剂的用于治疗肿瘤的组合
BR112018071023A2 (pt) 2016-04-15 2019-02-05 Felicitex Therapeutics Inc combinações para o tratamento de neoplasmas utilizando o direcionamento de células inativas e inibidores da mitose

Also Published As

Publication number Publication date
AU2023200428A1 (en) 2023-03-02
EP3442505A4 (en) 2019-12-18
AU2017248762A1 (en) 2018-11-01
WO2017181075A1 (en) 2017-10-19
US20190298723A1 (en) 2019-10-03
US11202779B2 (en) 2021-12-21
CN109562176A (zh) 2019-04-02
IL288777A (en) 2022-02-01
JP7123806B2 (ja) 2022-08-23
KR20180132882A (ko) 2018-12-12
MX2023000549A (es) 2023-02-13
CA3021021A1 (en) 2017-10-19
KR20230020565A (ko) 2023-02-10
BR112018071031A2 (pt) 2019-02-12
IL262323A (en) 2018-11-29
KR102494174B1 (ko) 2023-02-02
JP2019511554A (ja) 2019-04-25
US10322128B2 (en) 2019-06-18
JP2022145800A (ja) 2022-10-04
US20170296541A1 (en) 2017-10-19
EP3442505A1 (en) 2019-02-20
IL262323B (en) 2022-03-01
US20220110940A1 (en) 2022-04-14

Similar Documents

Publication Publication Date Title
MX2022012146A (es) Combinaciones para el tratamiento de neoplasias utilizando localizacion de celulas quiescentes e inhibidores de la mitosis.
MX2023000549A (es) Combinaciones para el tratamiento de neoplasias usando localizacion de celulas quiescentes e inhibidores de egfr.
PH12021500004A1 (en) Pd-1/pd-l1 inhibitors
PH12017500070A1 (en) Methods of treating cancer using tigit inhibitors and anti-cancer agents
PH12020551244A1 (en) Pd-1/pd-l1 inhibitors
EA201992251A1 (ru) Противораковые вакцины и способы лечения с их применением
PH12019502379A1 (en) Pd-1/pd-l1 inhibitors
BR112015011756A2 (pt) inibidores da glutamase e métodos de uso
PH12017502391A1 (en) Compositions and methods for inhibiting arginase activity
MX393818B (es) Terapias de combinación para el tratamiento de cáncer.
MX381582B (es) Terapia de combinacion para el tratamiento de neoplasias malignas.
MX2017010595A (es) Métodos, composiciones, y equipos para tratamiento de cáncer.
PH12016501550A1 (en) Combination of a pd-1 antagonist and an ido1 inhibitor for treating cancer
MX2015013177A (es) Combinacion de tratamientod de cancer usando microarns e inhibidores de egfr-tki.
MX2019013862A (es) Terapia de combinacion.
MX2020001727A (es) Terapia de combinacion.
MX394452B (es) Inhibicion de la actividad de olig2.
WO2017019721A3 (en) Combinations of ezh2 inhibitors with further agents for use in the treatment of cancer
ZA201901367B (en) Inhibition of olig2 activity
PH12016501838A1 (en) Compounds and their methods of use
MX2017013666A (es) Terapia de combinacion de agente anti-fuctactico y agente de inmunoterapia y composiciones para el tratamiento de cancer.
EA201592012A8 (ru) Применение флагеллина для улучшенной химиотерапии
JOP20180038A1 (ar) مثبطات pd-1/pd-l1
EA201992045A1 (ru) Ингибиторы pd-1/pd-l1
EA201691907A1 (ru) Комбинированная терапия кураксинами