MX2018011425A - Construcciones de anticuerpos de adn y método para utilizarlas. - Google Patents
Construcciones de anticuerpos de adn y método para utilizarlas.Info
- Publication number
- MX2018011425A MX2018011425A MX2018011425A MX2018011425A MX2018011425A MX 2018011425 A MX2018011425 A MX 2018011425A MX 2018011425 A MX2018011425 A MX 2018011425A MX 2018011425 A MX2018011425 A MX 2018011425A MX 2018011425 A MX2018011425 A MX 2018011425A
- Authority
- MX
- Mexico
- Prior art keywords
- same
- antibody constructs
- dna antibody
- combination
- nucleic acid
- Prior art date
Links
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical group 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
En la presente, se describe una composicion que comprende la combinacion de una secuencia de acido nucleico que codifica un polinucleotido deseado que provoca una respuesta inmunitaria en un mamifero y una secuencia de acido nucleico que codifica un anticuerpo, un fragmento de este, una variante de este, o una combinacion de estos.
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662311316P | 2016-03-21 | 2016-03-21 | |
US201662332381P | 2016-05-05 | 2016-05-05 | |
US201662376162P | 2016-08-17 | 2016-08-17 | |
US201662396748P | 2016-09-19 | 2016-09-19 | |
US201662396750P | 2016-09-19 | 2016-09-19 | |
US201662417093P | 2016-11-03 | 2016-11-03 | |
US201662429473P | 2016-12-02 | 2016-12-02 | |
US201662429454P | 2016-12-02 | 2016-12-02 | |
PCT/US2017/023479 WO2017165460A1 (en) | 2016-03-21 | 2017-03-29 | Dna antibody constructs and method of using same |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018011425A true MX2018011425A (es) | 2019-09-04 |
Family
ID=59900715
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018011425A MX2018011425A (es) | 2016-03-21 | 2017-03-21 | Construcciones de anticuerpos de adn y método para utilizarlas. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20190091322A1 (es) |
EP (1) | EP3432918A4 (es) |
JP (2) | JP2019509350A (es) |
KR (2) | KR20180138204A (es) |
CN (1) | CN109890407A (es) |
AU (1) | AU2017238168A1 (es) |
BR (1) | BR112018069297A2 (es) |
CA (1) | CA3018566A1 (es) |
MX (1) | MX2018011425A (es) |
SG (2) | SG11201808152PA (es) |
WO (1) | WO2017165460A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9789175B2 (en) * | 2013-03-15 | 2017-10-17 | The Trustees Of The University Of Pennsylvania | Synthetic immunogens for prophylaxis or treatment of tuberculosis |
AU2017261305A1 (en) * | 2016-05-05 | 2018-12-20 | Inovio Pharmaceuticals, Inc. | DNA monoclonal antibodies targeting influenza virus |
CA3035932A1 (en) * | 2016-09-14 | 2018-03-22 | Abbvie Biotherapeutics Inc. | Anti-pd-1 antibodies and their uses |
US11925685B2 (en) * | 2016-09-19 | 2024-03-12 | The Trustees Of The University Of Pennsylvania | DNA antibody constructs encoding anti-ZIKV envelope antibodies |
WO2018102657A1 (en) * | 2016-12-02 | 2018-06-07 | Weiner David B | Dna antibody constructs for use against ebola virus |
US20200216519A1 (en) * | 2017-09-15 | 2020-07-09 | The Wistar Institute Of Anatomy And Biology | Dna antibody constructs for use against ebola virus |
WO2019075300A2 (en) * | 2017-10-12 | 2019-04-18 | The Wistar Institute Of Anatomy And Biology | ANTIGENS MAYARO VIRUS CONSENSUS, DNA TYPE ANTIBODY CONSTRUCTS FOR USE AGAINST THE MAYARO VIRUS, AND THEIR COMBINATIONS |
US20210047388A1 (en) * | 2018-01-31 | 2021-02-18 | The Wistar Institute Of Anatomy And Biology | Nucleic acid antibody constructs for use against ebola virus |
WO2019152599A1 (en) * | 2018-01-31 | 2019-08-08 | The Wistar Institute Of Anatomy And Biology | Nucleic acid monoclonal antibodies targeting pcsk9 and methods of use |
WO2019152603A1 (en) * | 2018-01-31 | 2019-08-08 | The Wistar Institute Of Anatomy And Biology | Nucleic acid antibody constructs for use against zika virus |
US20220298211A1 (en) * | 2019-06-04 | 2022-09-22 | Qiang Chen | PLANT-PRODUCED mABs AGAINST CHIKUNGUNYA VIRUS WITH ENHANCED EFFECTOR FUNCTION AND EFFICACY |
WO2021226343A1 (en) * | 2020-05-07 | 2021-11-11 | The Wistar Institute Of Anatomy Andbiology | Dna antibody constructs for use against hepatitis b virus |
WO2021252519A1 (en) * | 2020-06-08 | 2021-12-16 | University Of Florida Research Foundation, Inc. | Materials and methods for the diagnosis and treatment of cancer |
WO2023183818A2 (en) * | 2022-03-21 | 2023-09-28 | University Of Georgia Research Foundation, Inc. | A novel h1n1 antibody |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9606425D0 (en) * | 1996-03-27 | 1996-06-05 | Binding Site Ltd | Improvements in and relating to the production of antibodies and test kits incorporating antibodies |
CN1480215A (zh) * | 2003-07-07 | 2004-03-10 | 叶新新 | Sars病毒抗原抗体复合疫苗及实验动物模型与方法 |
JP5744719B2 (ja) * | 2008-04-04 | 2015-07-08 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | チクングニヤウィルスタンパク質の共通配列、これをコードする核酸分子、並びにこれを使用する組成物および方法 |
US20110045534A1 (en) * | 2009-08-20 | 2011-02-24 | Cell Signaling Technology, Inc. | Nucleic Acid Cassette For Producing Recombinant Antibodies |
MX346784B (es) * | 2010-11-12 | 2017-03-31 | Inovio Pharmaceuticals Inc | Antigenos prostaticos de consenso, molecula de acido nucleico que los codifica y vacuna y usos que los comprenden. |
EA201591131A1 (ru) * | 2012-12-13 | 2015-12-30 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Днк-конструкции антитела и способ их применения |
CN105829341A (zh) * | 2013-12-13 | 2016-08-03 | 宾夕法尼亚大学理事会 | Dna抗体构建体及其使用方法 |
-
2017
- 2017-03-21 MX MX2018011425A patent/MX2018011425A/es unknown
- 2017-03-21 BR BR112018069297A patent/BR112018069297A2/pt unknown
- 2017-03-21 SG SG11201808152PA patent/SG11201808152PA/en unknown
- 2017-03-21 CA CA3018566A patent/CA3018566A1/en active Pending
- 2017-03-21 KR KR1020187030167A patent/KR20180138204A/ko not_active IP Right Cessation
- 2017-03-21 SG SG10202009182RA patent/SG10202009182RA/en unknown
- 2017-03-21 KR KR1020227045775A patent/KR20230012070A/ko not_active Application Discontinuation
- 2017-03-21 JP JP2019500741A patent/JP2019509350A/ja active Pending
- 2017-03-21 CN CN201780031478.2A patent/CN109890407A/zh active Pending
- 2017-03-21 AU AU2017238168A patent/AU2017238168A1/en active Pending
- 2017-03-21 US US16/087,146 patent/US20190091322A1/en active Pending
- 2017-03-21 EP EP17771020.9A patent/EP3432918A4/en active Pending
- 2017-03-29 WO PCT/US2017/023479 patent/WO2017165460A1/en active Application Filing
-
2022
- 2022-06-01 JP JP2022089687A patent/JP2022121440A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3432918A1 (en) | 2019-01-30 |
KR20230012070A (ko) | 2023-01-25 |
SG11201808152PA (en) | 2018-10-30 |
JP2019509350A (ja) | 2019-04-04 |
JP2022121440A (ja) | 2022-08-19 |
BR112018069297A2 (pt) | 2019-01-22 |
CN109890407A (zh) | 2019-06-14 |
EP3432918A4 (en) | 2020-02-12 |
US20190091322A1 (en) | 2019-03-28 |
SG10202009182RA (en) | 2020-11-27 |
KR20180138204A (ko) | 2018-12-28 |
WO2017165460A1 (en) | 2017-09-28 |
CA3018566A1 (en) | 2017-09-28 |
WO2017165460A9 (en) | 2017-11-09 |
AU2017238168A1 (en) | 2018-10-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2018011425A (es) | Construcciones de anticuerpos de adn y método para utilizarlas. | |
PH12019500540A1 (en) | Anti-pd-1 antibodies and their uses | |
PH12019501357A1 (en) | Anti-ox40 antibodies and their uses | |
CY1124806T1 (el) | Αντισωματα enanti-cd40 και χρησεις αυτων | |
PH12018501280A1 (en) | Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use | |
PH12017501115A1 (en) | Anti-myostatin antibodies, polypeptides containing variant fc regions, and method of use | |
PH12019501973A1 (en) | Anti-phf-tau antibodies and uses thereof | |
MX2017006094A (es) | Anticuerpos anti-interleucina-33 y sus usos. | |
MX2022001085A (es) | Anticuerpos anti-c1s humanizados y metodos para usarlos. | |
MX2018002106A (es) | Vacunas terapeuticas contra el hpv18. | |
WO2018035084A8 (en) | Monovalent asymmetric tandem fab bispecific antibodies | |
MX2016013985A (es) | Cepas de vacunas de listeria recombinante y metodos para producir las mismas. | |
MX2017016169A (es) | Anticuerpos anti-her2 y metodos de uso. | |
MX2017014397A (es) | Anticuerpos anti-receptor neonatal de fragmento cristalizable(fcrn). | |
MX2016010791A (es) | Inmunoterapia con multiples objetivos dirigida por biomarcadores. | |
MX2019013370A (es) | Constructos de anticuerpos de ácidos nucleicos optimizados. | |
WO2016172551A8 (en) | METHODS OF IDENTIFYING BACTERIA COMPRISING BINDING POLYPEPTIDES | |
MX2016017380A (es) | Antagonistas del anticuerpo interferon alfa y omega. | |
AU2015279552A8 (en) | Neural cells expressing adenovirus E4ORF1, and methods of making and using the same | |
PH12020550483A1 (en) | Anti-apoc3 antibodies and methods of use thereof | |
WO2014151834A3 (en) | Methods and compositions relating to anti-ccr7 antigen binding proteins | |
WO2018060368A3 (en) | COMPOSITIONS AND METHODS FOR ENHANCING STABILITY OF TRANSGENES IN POXVIRUSES | |
MX2023003934A (es) | Antigenos de consenso de filovirus, construcciones de acido nucleico y vacunas realizadas a partir de estos, y metodos para utilizarlos. | |
EA201892124A1 (ru) | Днк-конструкции антител и способы их применения | |
MX2018013521A (es) | Anticuerpos monoclonales de adn dirigidos al virus de la influenza. |