MX2018009895A - Plantas que muestran una reduccion en el cambio de coloracion en la superficie inducido por heridas. - Google Patents
Plantas que muestran una reduccion en el cambio de coloracion en la superficie inducido por heridas.Info
- Publication number
- MX2018009895A MX2018009895A MX2018009895A MX2018009895A MX2018009895A MX 2018009895 A MX2018009895 A MX 2018009895A MX 2018009895 A MX2018009895 A MX 2018009895A MX 2018009895 A MX2018009895 A MX 2018009895A MX 2018009895 A MX2018009895 A MX 2018009895A
- Authority
- MX
- Mexico
- Prior art keywords
- gene
- modified
- induced
- plant
- induced surface
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
- A01H6/14—Asteraceae or Compositae, e.g. safflower, sunflower, artichoke or lettuce
- A01H6/1472—Lactuca sativa [lettuce]
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F11/00—Error detection; Error correction; Monitoring
- G06F11/07—Responding to the occurrence of a fault, e.g. fault tolerance
- G06F11/14—Error detection or correction of the data by redundancy in operation
- G06F11/1402—Saving, restoring, recovering or retrying
- G06F11/1446—Point-in-time backing up or restoration of persistent data
- G06F11/1458—Management of the backup or restore process
- G06F11/1464—Management of the backup or restore process for networked environments
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
- A01H5/12—Leaves
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8249—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving ethylene biosynthesis, senescence or fruit development, e.g. modified tomato ripening, cut flower shelf-life
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/13—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen (1.14.13)
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F11/00—Error detection; Error correction; Monitoring
- G06F11/07—Responding to the occurrence of a fault, e.g. fault tolerance
- G06F11/14—Error detection or correction of the data by redundancy in operation
- G06F11/1479—Generic software techniques for error detection or fault masking
- G06F11/1482—Generic software techniques for error detection or fault masking by means of middleware or OS functionality
- G06F11/1484—Generic software techniques for error detection or fault masking by means of middleware or OS functionality involving virtual machines
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F11/00—Error detection; Error correction; Monitoring
- G06F11/07—Responding to the occurrence of a fault, e.g. fault tolerance
- G06F11/16—Error detection or correction of the data by redundancy in hardware
- G06F11/20—Error detection or correction of the data by redundancy in hardware using active fault-masking, e.g. by switching out faulty elements or by switching in spare elements
- G06F11/2053—Error detection or correction of the data by redundancy in hardware using active fault-masking, e.g. by switching out faulty elements or by switching in spare elements where persistent mass storage functionality or persistent mass storage control functionality is redundant
- G06F11/2056—Error detection or correction of the data by redundancy in hardware using active fault-masking, e.g. by switching out faulty elements or by switching in spare elements where persistent mass storage functionality or persistent mass storage control functionality is redundant by mirroring
- G06F11/2071—Error detection or correction of the data by redundancy in hardware using active fault-masking, e.g. by switching out faulty elements or by switching in spare elements where persistent mass storage functionality or persistent mass storage control functionality is redundant by mirroring using a plurality of controllers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0073—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen 1.14.13
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/13—Plant traits
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Theoretical Computer Science (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Physiology (AREA)
- Developmental Biology & Embryology (AREA)
- Environmental Sciences (AREA)
- General Physics & Mathematics (AREA)
- Quality & Reliability (AREA)
- Nutrition Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Fruits And Vegetables (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Mycology (AREA)
- Retry When Errors Occur (AREA)
- Hardware Redundancy (AREA)
Abstract
La presente invención se relaciona con una planta que comprende un homólogo de gen F5H modificado, en donde el homólogo de gen comprende una modificación en comparación con su homólogo de gen F5H de tipo silvestre correspondiente, en donde la presencia del homólogo de gen F5H modificado en la planta da como resultado una reducción en el cambio de coloración de superficie inducida por heridas en comparación con una planta que no comprende el homólogo de gen F5H modificado. La invención también se relaciona con un homólogo de gen F5H modificado que da como resultado cambio de coloración en la superficie, inducido por heridas, reducido. La invención se relaciona adicionalmente con el uso de un gen en la crianza y producción de plantas que muestran cambio de coloración en la superficie inducido por heridas reducido.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EPPCT/EP2016/053895 | 2016-02-24 | ||
| EP2016053999 | 2016-02-25 | ||
| PCT/EP2017/054343 WO2017144669A1 (en) | 2016-02-24 | 2017-02-24 | Plants showing a reduced wound-induced surface discoloration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2018009895A true MX2018009895A (es) | 2018-09-11 |
| MX393975B MX393975B (es) | 2025-03-24 |
Family
ID=58162597
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018009895A MX393975B (es) | 2016-02-24 | 2017-02-24 | Plantas que muestran una reducción en el cambio de coloración en la superficie inducido por heridas. |
| MX2022008433A MX2022008433A (es) | 2016-02-24 | 2018-08-15 | Plantas que muestran una reduccion en el cambio de coloracion en la superficie inducido por heridas. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022008433A MX2022008433A (es) | 2016-02-24 | 2018-08-15 | Plantas que muestran una reduccion en el cambio de coloracion en la superficie inducido por heridas. |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10731174B2 (es) |
| EP (2) | EP3419416B1 (es) |
| JP (3) | JP7186618B2 (es) |
| CN (2) | CN115956507A (es) |
| AU (1) | AU2017222296B2 (es) |
| ES (1) | ES3036879T3 (es) |
| GB (1) | GB2608931A (es) |
| MX (2) | MX393975B (es) |
| WO (1) | WO2017144669A1 (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115956507A (zh) * | 2016-02-24 | 2023-04-14 | 瑞克斯旺种苗集团公司 | 显示减少的伤口诱导的表面变色的植物 |
| US20200068831A1 (en) | 2018-10-10 | 2020-03-05 | Nunhems B.V. | Lettuce variety nun 06132 ltl |
| US11224178B2 (en) | 2018-10-10 | 2022-01-18 | Nunhems B.V. | Lettuce variety NUN 01201 LTL |
| US11206779B2 (en) | 2018-10-10 | 2021-12-28 | Nunhems B.V. | Lettuce variety NUN 09111 LTL |
| CN109999202B (zh) * | 2019-01-18 | 2022-03-22 | 南阳师范学院 | 一种介导紫杉醇递送的多功能肽及其应用 |
| US11266089B2 (en) | 2019-08-02 | 2022-03-08 | Nunhems B.V. | Lettuce variety NUN 06237 LTL |
| US11503785B2 (en) | 2019-08-02 | 2022-11-22 | Nunhems B.V. | Lettuce variety NUN 09164 LTL |
| US11234390B2 (en) | 2019-08-02 | 2022-02-01 | Nunhems B.V. | Lettuce variety NUN 08208 LTL |
| US11445672B2 (en) | 2019-08-02 | 2022-09-20 | Nunhems B.V. | Lettuce variety nun 09093 LTL |
| WO2021046155A1 (en) * | 2019-09-03 | 2021-03-11 | Voyager Therapeutics, Inc. | Vectorized editing of nucleic acids to correct overt mutations |
| US11357187B2 (en) | 2019-11-22 | 2022-06-14 | Nunhems B.V. | Lettuce variety NUN 06186 LTL |
| US11547072B2 (en) | 2019-11-22 | 2023-01-10 | Nunhems B.V. | Lettuce variety NUN 09161 LTL |
| US11470795B2 (en) | 2019-11-22 | 2022-10-18 | Nunhems B.V. | Lettuce variety NUN 08223 LTL |
| US11399478B2 (en) | 2019-11-22 | 2022-08-02 | Nunhems B.V. | Lettuce variety NUN 08204 LTL |
| US11672217B2 (en) | 2020-07-30 | 2023-06-13 | Nunhems B.V. | Lettuce variety NUN 06574 LTL |
| US20220030790A1 (en) | 2020-07-30 | 2022-02-03 | Nunhems B.V. | Lettuce variety nun 09173 ltl |
| US11930753B2 (en) | 2020-08-13 | 2024-03-19 | Nunhems B.V. | Lettuce variety NUN 08230 LTL |
| US11576324B2 (en) | 2020-08-14 | 2023-02-14 | Nunhems B.V. | Lettuce variety NUN 09166 LTL |
| KR102272557B1 (ko) * | 2020-11-25 | 2021-07-05 | 주식회사 툴젠 | CRISPR/Cas9 시스템을 이용한 갈변 억제 감자 식물체의 제조방법 |
| US11957099B2 (en) | 2021-02-25 | 2024-04-16 | Nunhems B.V. | Lettuce variety NUN 06299 LTL |
| US12396415B2 (en) | 2021-11-10 | 2025-08-26 | Nunhems B.V. | Lettuce variety NUN 09187 LTL |
| US12137653B2 (en) | 2021-11-30 | 2024-11-12 | Nunhems B.V. | Lettuce variety NUN 06529 LTL |
| US12336471B2 (en) | 2021-11-30 | 2025-06-24 | Nunhems B.V. | Lettuce variety NUN 08235 LTL |
| US12356914B2 (en) | 2021-12-02 | 2025-07-15 | Nunhems B.V. | Lettuce variety NUN 08224 LTL |
| CN114763549B (zh) * | 2021-12-23 | 2023-09-29 | 西藏自治区农牧科学院农业研究所 | 一种青稞抗旱相关基因及鉴别抗旱青稞的试剂盒和方法 |
| WO2024114891A1 (en) | 2022-11-29 | 2024-06-06 | Bejo Zaden B.V. | No bleed lettuce |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040023262A1 (en) * | 2002-03-05 | 2004-02-05 | Pioneer Hi-Bred International, Inc. | Targeted manipulation of genes in plants |
| US7799906B1 (en) * | 2004-09-22 | 2010-09-21 | Arborgen, Llc | Compositions and methods for modulating lignin of a plant |
| CA2636084C (en) * | 2006-01-06 | 2021-11-02 | Rijk Zwaan Zaadteelt En Zaadhandel B.V. | Screening method for selecting plants that show a reduced wound-induced surface discolouration and plant and plant parts thus obtained |
| EP1973396B1 (en) * | 2006-01-06 | 2013-03-13 | Rijk Zwaan Zaadteelt en Zaadhandel B.V. | Screening method for selecting plants that show a reduced wound-induced surface discolouration and plant and plant parts thus obtained |
| US9309528B2 (en) * | 2006-11-21 | 2016-04-12 | The Samuel Roberts Noble Foundation, Inc. | Biofuel production methods and compositions |
| CN101041821A (zh) * | 2007-02-16 | 2007-09-26 | 中国农业科学院油料作物研究所 | 甘蓝型油菜木质素单体合成基因f5h及应用 |
| EP2011389A1 (en) * | 2007-07-06 | 2009-01-07 | Rijk Zwaan Zaadteelt en Zaadhandel B.V. | Method for identifying plant material that shows a reduced discolouration, plants thus identified and use of the identified plants for the production of commercial crop plants showing a reduced discolouration |
| US8898518B2 (en) * | 2010-05-18 | 2014-11-25 | Vmware, Inc. | Method and system for enabling checkpointing fault tolerance across remote virtual machines |
| AR085759A1 (es) * | 2011-04-21 | 2013-10-23 | Basf Plant Science Co Gmbh | Metodos para modificar la biosintesis de la lignina y mejorar la digestibilidad |
| US9814210B2 (en) * | 2014-04-08 | 2017-11-14 | Rijk Zwaan Zaadteelt En Zaadhandel B.V. | Lettuce variety 41-187 RZ |
| US9977704B1 (en) * | 2014-09-26 | 2018-05-22 | EMC IP Holding Company LLC | Automated backup and replication of virtual machine data centers |
| CN115956507A (zh) * | 2016-02-24 | 2023-04-14 | 瑞克斯旺种苗集团公司 | 显示减少的伤口诱导的表面变色的植物 |
| US11074143B2 (en) * | 2018-10-05 | 2021-07-27 | Rubrik, Inc. | Data backup and disaster recovery between environments |
-
2017
- 2017-02-24 CN CN202211323649.8A patent/CN115956507A/zh active Pending
- 2017-02-24 AU AU2017222296A patent/AU2017222296B2/en active Active
- 2017-02-24 EP EP17707291.5A patent/EP3419416B1/en active Active
- 2017-02-24 MX MX2018009895A patent/MX393975B/es unknown
- 2017-02-24 ES ES17707291T patent/ES3036879T3/es active Active
- 2017-02-24 WO PCT/EP2017/054343 patent/WO2017144669A1/en not_active Ceased
- 2017-02-24 CN CN201780013778.8A patent/CN108882692B/zh active Active
- 2017-02-24 JP JP2018544558A patent/JP7186618B2/ja active Active
- 2017-02-24 EP EP25181692.2A patent/EP4600374A3/en active Pending
-
2018
- 2018-08-15 MX MX2022008433A patent/MX2022008433A/es unknown
- 2018-08-21 US US16/106,684 patent/US10731174B2/en active Active
-
2020
- 2020-02-11 US US16/787,231 patent/US11702669B2/en active Active
-
2021
- 2021-04-15 JP JP2021069275A patent/JP2021118709A/ja active Pending
- 2021-04-26 GB GB2214587.4A patent/GB2608931A/en active Pending
-
2023
- 2023-03-15 JP JP2023040749A patent/JP7741119B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES3036879T3 (en) | 2025-09-25 |
| JP2023078288A (ja) | 2023-06-06 |
| AU2017222296B2 (en) | 2023-04-27 |
| EP3419416B1 (en) | 2025-06-11 |
| MX2022008433A (es) | 2022-08-02 |
| US20200165624A1 (en) | 2020-05-28 |
| JP7186618B2 (ja) | 2022-12-09 |
| CN108882692A (zh) | 2018-11-23 |
| MX393975B (es) | 2025-03-24 |
| US11702669B2 (en) | 2023-07-18 |
| GB2608931A (en) | 2023-01-18 |
| CN108882692B (zh) | 2022-10-28 |
| EP3419416A1 (en) | 2019-01-02 |
| US10731174B2 (en) | 2020-08-04 |
| JP2021118709A (ja) | 2021-08-12 |
| GB202214587D0 (en) | 2022-11-16 |
| JP7741119B2 (ja) | 2025-09-17 |
| EP4600374A2 (en) | 2025-08-13 |
| JP2019507595A (ja) | 2019-03-22 |
| AU2017222296A1 (en) | 2018-08-09 |
| WO2017144669A1 (en) | 2017-08-31 |
| EP4600374A3 (en) | 2025-10-22 |
| US20190136255A1 (en) | 2019-05-09 |
| CN115956507A (zh) | 2023-04-14 |
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