MX2018009829A - Purificacion de proteinas. - Google Patents
Purificacion de proteinas.Info
- Publication number
- MX2018009829A MX2018009829A MX2018009829A MX2018009829A MX2018009829A MX 2018009829 A MX2018009829 A MX 2018009829A MX 2018009829 A MX2018009829 A MX 2018009829A MX 2018009829 A MX2018009829 A MX 2018009829A MX 2018009829 A MX2018009829 A MX 2018009829A
- Authority
- MX
- Mexico
- Prior art keywords
- protein purification
- purification
- protein
- semi
- collected
- Prior art date
Links
- 238000001742 protein purification Methods 0.000 title 1
- 238000011210 chromatographic step Methods 0.000 abstract 1
- 239000012504 chromatography matrix Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente invención se refiere a un proceso para la purificación de una proteína que comprende una etapa de cromatografía semi-continua mediante la cual el flujo continuo se recolecta y vuelve a cargar en la matriz de cromatografía.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1602938.1A GB201602938D0 (en) | 2016-02-19 | 2016-02-19 | Protein purification |
| PCT/EP2017/053677 WO2017140881A1 (en) | 2016-02-19 | 2017-02-17 | Protein purification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018009829A true MX2018009829A (es) | 2018-09-11 |
Family
ID=55752913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018009829A MX2018009829A (es) | 2016-02-19 | 2017-02-17 | Purificacion de proteinas. |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US20190202859A1 (es) |
| EP (2) | EP3416974B1 (es) |
| JP (1) | JP6911040B2 (es) |
| KR (1) | KR102728998B1 (es) |
| CN (1) | CN108779143B (es) |
| AU (1) | AU2017220675B2 (es) |
| CA (1) | CA3014488A1 (es) |
| CL (1) | CL2018002373A1 (es) |
| CO (1) | CO2018009057A2 (es) |
| CY (1) | CY1123802T1 (es) |
| DK (2) | DK3730511T3 (es) |
| EA (1) | EA038538B1 (es) |
| ES (2) | ES2960723T3 (es) |
| FI (1) | FI3730511T3 (es) |
| GB (1) | GB201602938D0 (es) |
| HR (2) | HRP20231432T1 (es) |
| HU (2) | HUE050774T2 (es) |
| IL (1) | IL261040B (es) |
| LT (2) | LT3730511T (es) |
| MX (1) | MX2018009829A (es) |
| MY (1) | MY186560A (es) |
| PL (2) | PL3416974T3 (es) |
| PT (2) | PT3730511T (es) |
| RU (1) | RU2018133009A (es) |
| SG (1) | SG11201806852PA (es) |
| SI (2) | SI3730511T1 (es) |
| WO (1) | WO2017140881A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR102198A1 (es) | 2014-10-09 | 2017-02-08 | Regeneron Pharma | Proceso para reducir partículas subvisibles en una formulación farmacéutica |
| MX2019000935A (es) | 2016-08-16 | 2019-07-04 | Regeneron Pharma | Metodos para cuantificar anticuerpos individuales de una mezcla. |
| PL3532838T3 (pl) | 2016-10-25 | 2022-10-03 | Regeneron Pharmaceuticals, Inc. | Metody i systemy analizy danych chromatograficznych |
| MA47106A (fr) | 2016-12-21 | 2019-10-30 | Amgen Inc | Formulations d'anticorps anti-tnf alpha |
| GB201711481D0 (en) * | 2017-07-17 | 2017-08-30 | Ucb Biopharma Sprl | Protein purification |
| EP3684415A1 (en) | 2017-09-19 | 2020-07-29 | Regeneron Pharmaceuticals, Inc. | Methods of reducing particle formation and compositions formed thereby |
| GB201805142D0 (en) * | 2018-03-29 | 2018-05-16 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| TWI853823B (zh) | 2018-07-02 | 2024-09-01 | 美商里珍納龍藥品有限公司 | 自混合物製備多肽之系統及方法 |
| JP7063759B2 (ja) * | 2018-07-25 | 2022-05-09 | 株式会社日立プラントサービス | 精製装置 |
| CN110348089B (zh) * | 2019-06-28 | 2021-05-04 | 浙江大学 | 基于层析模型实现多柱连续流层析设计及分析的方法 |
| EP4587144A1 (en) * | 2022-09-13 | 2025-07-23 | Sanofi-Aventis Deutschland GmbH | Continuous gradient elution chromatographic fractionation |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6055162B2 (ja) * | 1977-05-26 | 1985-12-04 | 参松工業株式会社 | カラムクロマト分離法 |
| US9433922B2 (en) * | 2007-08-14 | 2016-09-06 | Emd Millipore Corporation | Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same |
| WO2009045897A1 (en) * | 2007-10-03 | 2009-04-09 | Dyax Corp. | Systems and methods for purifying proteins |
| CN101318991A (zh) | 2008-07-04 | 2008-12-10 | 陈志南 | 一种采用复合层析介质纯化Fc融合蛋白的方法 |
| GB201012603D0 (en) * | 2010-07-27 | 2010-09-08 | Ucb Pharma Sa | Protein purification |
| WO2012057676A1 (en) * | 2010-10-27 | 2012-05-03 | Ge Healthcare Bio-Sciences Ab | Chromatography system with guard columns |
| EP2748178B1 (en) * | 2011-08-25 | 2018-10-31 | F. Hoffmann-La Roche AG | Cation and anion exchange chromatography method |
| LT2776466T (lt) | 2011-11-11 | 2017-11-27 | Ucb Biopharma Sprl | Albuminą prisijungiantys antikūnai ir jų prisijungimo fragmentai |
| AU2013384204B2 (en) * | 2013-03-14 | 2017-03-16 | Abbvie Inc. | Low acidic species compositions and methods for producing and using the same |
-
2016
- 2016-02-19 GB GBGB1602938.1A patent/GB201602938D0/en not_active Ceased
-
2017
- 2017-02-17 EA EA201891878A patent/EA038538B1/ru unknown
- 2017-02-17 FI FIEP20179961.6T patent/FI3730511T3/fi active
- 2017-02-17 CN CN201780018403.0A patent/CN108779143B/zh active Active
- 2017-02-17 LT LTEP20179961.6T patent/LT3730511T/lt unknown
- 2017-02-17 HU HUE17706215A patent/HUE050774T2/hu unknown
- 2017-02-17 JP JP2018543619A patent/JP6911040B2/ja active Active
- 2017-02-17 HR HRP20231432TT patent/HRP20231432T1/hr unknown
- 2017-02-17 US US15/999,655 patent/US20190202859A1/en not_active Abandoned
- 2017-02-17 DK DK20179961.6T patent/DK3730511T3/da active
- 2017-02-17 SG SG11201806852PA patent/SG11201806852PA/en unknown
- 2017-02-17 ES ES20179961T patent/ES2960723T3/es active Active
- 2017-02-17 PT PT201799616T patent/PT3730511T/pt unknown
- 2017-02-17 SI SI201731428T patent/SI3730511T1/sl unknown
- 2017-02-17 WO PCT/EP2017/053677 patent/WO2017140881A1/en not_active Ceased
- 2017-02-17 KR KR1020187027129A patent/KR102728998B1/ko active Active
- 2017-02-17 CA CA3014488A patent/CA3014488A1/en active Pending
- 2017-02-17 DK DK17706215.5T patent/DK3416974T3/da active
- 2017-02-17 PL PL17706215T patent/PL3416974T3/pl unknown
- 2017-02-17 PT PT177062155T patent/PT3416974T/pt unknown
- 2017-02-17 ES ES17706215T patent/ES2822918T3/es active Active
- 2017-02-17 MY MYPI2018702843A patent/MY186560A/en unknown
- 2017-02-17 EP EP17706215.5A patent/EP3416974B1/en active Active
- 2017-02-17 AU AU2017220675A patent/AU2017220675B2/en active Active
- 2017-02-17 SI SI201730429T patent/SI3416974T1/sl unknown
- 2017-02-17 LT LTEP17706215.5T patent/LT3416974T/lt unknown
- 2017-02-17 HR HRP20201415TT patent/HRP20201415T1/hr unknown
- 2017-02-17 PL PL20179961.6T patent/PL3730511T3/pl unknown
- 2017-02-17 MX MX2018009829A patent/MX2018009829A/es unknown
- 2017-02-17 HU HUE20179961A patent/HUE064240T2/hu unknown
- 2017-02-17 EP EP20179961.6A patent/EP3730511B1/en active Active
- 2017-02-17 RU RU2018133009A patent/RU2018133009A/ru not_active Application Discontinuation
-
2018
- 2018-08-07 IL IL261040A patent/IL261040B/en unknown
- 2018-08-17 CL CL2018002373A patent/CL2018002373A1/es unknown
- 2018-08-28 CO CONC2018/0009057A patent/CO2018009057A2/es unknown
-
2020
- 2020-10-22 CY CY20201101003T patent/CY1123802T1/el unknown
-
2021
- 2021-05-24 US US17/327,865 patent/US11905310B2/en active Active
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