MX2018009221A - Metodo para medir rasgos de flujo en un inhalador, inhalador y sistema. - Google Patents

Metodo para medir rasgos de flujo en un inhalador, inhalador y sistema.

Info

Publication number
MX2018009221A
MX2018009221A MX2018009221A MX2018009221A MX2018009221A MX 2018009221 A MX2018009221 A MX 2018009221A MX 2018009221 A MX2018009221 A MX 2018009221A MX 2018009221 A MX2018009221 A MX 2018009221A MX 2018009221 A MX2018009221 A MX 2018009221A
Authority
MX
Mexico
Prior art keywords
inhaler
capsule
feature
computing device
impact
Prior art date
Application number
MX2018009221A
Other languages
English (en)
Spanish (es)
Inventor
Ziegler Dominik
Pavkov Richard
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55272287&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2018009221(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2018009221A publication Critical patent/MX2018009221A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008—Electronic counters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/14—Detection of the presence or absence of a tube, a connector or a container in an apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/332—Force measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3327—Measuring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3334—Measuring or controlling the flow rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3375—Acoustical, e.g. ultrasonic, measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3553—Range remote, e.g. between patient's home and doctor's office
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3569—Range sublocal, e.g. between console and disposable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A61M2205/3592—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using telemetric means, e.g. radio or optical transmission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502—User interfaces, e.g. screens or keyboards
    • A61M2205/505—Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502—User interfaces, e.g. screens or keyboards
    • A61M2205/507—Head Mounted Displays [HMD]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/40—Respiratory characteristics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2018009221A 2016-01-28 2017-01-23 Metodo para medir rasgos de flujo en un inhalador, inhalador y sistema. MX2018009221A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16153186.8A EP3199193B1 (en) 2016-01-28 2016-01-28 Method for measuring flow features in an inhaler, inhaler and system
PCT/EP2017/051323 WO2017129521A1 (en) 2016-01-28 2017-01-23 Method for measuring flow features in an inhaler, inhaler and system

Publications (1)

Publication Number Publication Date
MX2018009221A true MX2018009221A (es) 2018-09-21

Family

ID=55272287

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018009221A MX2018009221A (es) 2016-01-28 2017-01-23 Metodo para medir rasgos de flujo en un inhalador, inhalador y sistema.

Country Status (19)

Country Link
US (1) US20190030262A1 (ja)
EP (2) EP3199193B1 (ja)
JP (1) JP7096154B2 (ja)
KR (1) KR20180103924A (ja)
CN (1) CN108601917B (ja)
AU (1) AU2017211903B2 (ja)
CA (1) CA3011543A1 (ja)
CY (1) CY1123380T1 (ja)
DK (2) DK3199193T3 (ja)
ES (2) ES2831451T3 (ja)
HR (2) HRP20220847T1 (ja)
HU (2) HUE051868T2 (ja)
LT (2) LT3199193T (ja)
MX (1) MX2018009221A (ja)
PL (2) PL3199193T3 (ja)
PT (2) PT3199193T (ja)
RU (1) RU2751814C2 (ja)
SI (2) SI3199193T1 (ja)
WO (1) WO2017129521A1 (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2877871C (en) 2012-06-25 2022-12-06 Gecko Health Innovations, Inc. Devices, systems, and methods for adherence monitoring and patient interaction
ES2816158T3 (es) 2013-08-28 2021-03-31 Gecko Health Innovations Inc Dispositivos, sistemas y métodos para monitorizar el cumplimiento y dispositivos, sistemas y métodos para monitorizar el uso de dispensadores de consumibles
EA036644B1 (ru) 2014-08-28 2020-12-03 Майкродоуз Терапьютикс, Инк. Приводимый в действие спокойным дыханием ингалятор сухого порошка с активацией с помощью миниатюрного датчика давления
AR101720A1 (es) 2014-08-28 2017-01-11 Microdose Therapeutx Inc Módulo de monitoreo de la docilidad para un inhalador
WO2016033419A1 (en) 2014-08-28 2016-03-03 Microdose Therapeutx, Inc. Compliance monitoring module for a breath-actuated inhaler
GB201420039D0 (en) 2014-11-11 2014-12-24 Teva Uk Ltd System for training a user in administering a medicament
US10058661B2 (en) 2014-12-04 2018-08-28 Norton (Waterford) Limited Inhalation monitoring system and method
ES2897697T3 (es) 2015-07-03 2022-03-02 Novartis Ag Inhalador adaptado para leer información almacenada en un medio de almacenamiento de datos de un recipiente
CN114159656A (zh) 2016-11-18 2022-03-11 诺顿（沃特福特）有限公司 吸入器
EP3552646B1 (en) 2016-11-18 2021-07-07 Norton (Waterford) Limited Drug delivery device with electronics
US11419995B2 (en) * 2019-04-30 2022-08-23 Norton (Waterford) Limited Inhaler system
CA3138446A1 (en) 2019-04-30 2020-11-05 Norton (Waterford) Limited Inhaler system
CN114025815A (zh) 2019-05-17 2022-02-08 诺尔顿沃特福德有限公司 具有电子器件的药物递送设备
EP3789065B1 (en) 2019-09-09 2022-06-22 Presspart Gmbh & Co. Kg An electronic system comprising a dry powder inhaler and an external device
US11464923B2 (en) 2020-06-19 2022-10-11 Norton (Waterford) Limited Inhaler system

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6099481A (en) * 1997-11-03 2000-08-08 Ntc Technology, Inc. Respiratory profile parameter determination method and apparatus
EP1718354B1 (en) * 2004-02-24 2020-04-29 MicroDose Therapeutx, Inc. Inhaler with a directional flow sensor
GB0410712D0 (en) 2004-05-13 2004-06-16 Novartis Ag Organic compounds
JP2006153760A (ja) * 2004-11-30 2006-06-15 Osaka Prefecture 周期運動体の状態監視方法、監視装置、監視システム、コンピュータプログラム及び記録媒体
ATE540715T1 (de) 2006-03-07 2012-01-15 Bang & Olufsen Medicom As Akustische inhalator-flussmessung
NZ575943A (en) * 2009-04-01 2009-07-31 Nexus6 Ltd Improvements in or Relating to Medicament Delivery Devices
US9016147B2 (en) * 2009-11-03 2015-04-28 Mannkind Corporation Apparatus and method for simulating inhalation efforts
JP5135367B2 (ja) 2010-02-24 2013-02-06 関西電力株式会社 流量計測装置及び方法
GB201006901D0 (en) 2010-04-26 2010-06-09 Sagentia Ltd Device for monitoring status and use of an inhalation or nasal drug delivery device
PT2686049E (pt) 2011-03-15 2015-07-06 Novartis Ag Inalador
WO2013016784A1 (en) * 2011-08-04 2013-02-07 Victor Esteve Dry powder inhaler
WO2013063449A1 (en) 2011-10-27 2013-05-02 Aldana Mark W Handheld therapeutic gas delivery
EP2890301B1 (en) 2012-08-29 2019-10-09 The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin System for monitoring use of a device
CN106794325B (zh) 2014-02-21 2020-06-30 瑞必治公司 粉末吸入器、系统和方法
WO2016033419A1 (en) * 2014-08-28 2016-03-03 Microdose Therapeutx, Inc. Compliance monitoring module for a breath-actuated inhaler
KR101619611B1 (ko) * 2014-09-22 2016-05-19 순천향대학교 산학협력단 마이크로폰을 이용한 호흡률 추정 장치 및 기법

Also Published As

Publication number Publication date
PL3407945T3 (pl) 2022-10-03
RU2751814C2 (ru) 2021-07-19
DK3199193T3 (da) 2020-10-26
AU2017211903A1 (en) 2018-07-19
PT3407945T (pt) 2022-07-13
HUE051868T2 (hu) 2021-03-29
US20190030262A1 (en) 2019-01-31
HUE059191T2 (hu) 2022-10-28
PL3199193T3 (pl) 2020-11-30
AU2017211903B2 (en) 2019-11-14
ES2831451T3 (es) 2021-06-08
EP3199193A1 (en) 2017-08-02
JP7096154B2 (ja) 2022-07-05
KR20180103924A (ko) 2018-09-19
PT3199193T (pt) 2020-10-22
LT3199193T (lt) 2020-10-12
HRP20220847T1 (hr) 2022-10-14
RU2018130824A3 (ja) 2020-04-27
JP2019506939A (ja) 2019-03-14
SI3407945T1 (sl) 2022-08-31
CA3011543A1 (en) 2017-08-03
EP3407945A1 (en) 2018-12-05
WO2017129521A1 (en) 2017-08-03
ES2921606T3 (es) 2022-08-30
CN108601917B (zh) 2022-01-18
CY1123380T1 (el) 2021-12-31
HRP20201668T1 (hr) 2020-12-25
CN108601917A (zh) 2018-09-28
EP3407945B1 (en) 2022-05-04
RU2018130824A (ru) 2020-02-28
LT3407945T (lt) 2022-08-25
SI3199193T1 (sl) 2020-12-31
DK3407945T3 (da) 2022-07-25
EP3199193B1 (en) 2020-08-26
BR112018014614A2 (pt) 2018-12-11

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