MX2017009768A - Ligadores lábiles para detección de biomarcadores. - Google Patents

Ligadores lábiles para detección de biomarcadores.

Info

Publication number
MX2017009768A
MX2017009768A MX2017009768A MX2017009768A MX2017009768A MX 2017009768 A MX2017009768 A MX 2017009768A MX 2017009768 A MX2017009768 A MX 2017009768A MX 2017009768 A MX2017009768 A MX 2017009768A MX 2017009768 A MX2017009768 A MX 2017009768A
Authority
MX
Mexico
Prior art keywords
biomarker detection
labile linkers
detection
labile
linkers
Prior art date
Application number
MX2017009768A
Other languages
English (en)
Inventor
A Heller Daniel
J Morin Trevor
b dunbar William
Shropshire Tyler
Original Assignee
Two Pore Guys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Two Pore Guys Inc filed Critical Two Pore Guys Inc
Publication of MX2017009768A publication Critical patent/MX2017009768A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/14—Streptococcus; Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/988—Lyases (4.), e.g. aldolases, heparinase, enolases, fumarase

Abstract

Se describen en la presente métodos y composiciones para detección y/o cuantificación electrónica de enzimas o actividad enzimática en una muestra utilizando un sistema de poros.
MX2017009768A 2015-02-02 2016-02-02 Ligadores lábiles para detección de biomarcadores. MX2017009768A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562111073P 2015-02-02 2015-02-02
PCT/US2016/016235 WO2016126748A1 (en) 2015-02-02 2016-02-02 Labile linkers for biomarker detection

Publications (1)

Publication Number Publication Date
MX2017009768A true MX2017009768A (es) 2017-12-11

Family

ID=56564619

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017009768A MX2017009768A (es) 2015-02-02 2016-02-02 Ligadores lábiles para detección de biomarcadores.

Country Status (12)

Country Link
US (1) US20180023114A1 (es)
EP (1) EP3254109A4 (es)
JP (1) JP2018503830A (es)
KR (1) KR20170109046A (es)
CN (1) CN107209182A (es)
AU (1) AU2016215455A1 (es)
CA (1) CA2973729A1 (es)
HK (1) HK1244318A1 (es)
IL (1) IL253382A0 (es)
MX (1) MX2017009768A (es)
RU (1) RU2712245C2 (es)
WO (1) WO2016126748A1 (es)

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US8870950B2 (en) 2009-12-08 2014-10-28 Mitral Tech Ltd. Rotation-based anchoring of an implant
US11653910B2 (en) 2010-07-21 2023-05-23 Cardiovalve Ltd. Helical anchor implantation
EP2948103B1 (en) 2013-01-24 2022-12-07 Cardiovalve Ltd Ventricularly-anchored prosthetic valves
KR102245192B1 (ko) * 2013-05-06 2021-04-29 온테라 인크. 나노포어를 이용한 표적 검출
ES2704902T3 (es) 2013-05-06 2019-03-20 Two Pore Guys Inc Un método de detección de objetivos biológicos usando un nanoporo y un agente de unión a proteínas de fusión
CN110141399B (zh) 2015-02-05 2021-07-27 卡迪尔维尔福股份有限公司 带有轴向滑动框架的人工瓣膜
JP2018537673A (ja) * 2015-11-23 2018-12-20 ツー ポア ガイズ インコーポレイテッド 追跡及び検出のための標的修飾
US10531866B2 (en) 2016-02-16 2020-01-14 Cardiovalve Ltd. Techniques for providing a replacement valve and transseptal communication
US11486873B2 (en) 2016-03-31 2022-11-01 Ontera Inc. Multipore determination of fractional abundance of polynucleotide sequences in a sample
WO2018029680A1 (en) 2016-08-10 2018-02-15 Mitraltech Ltd. Prosthetic valve with concentric frames
CN109564185A (zh) 2016-10-24 2019-04-02 双孔人公司 样品中多核苷酸序列的分数丰度
US10888421B2 (en) 2017-09-19 2021-01-12 Cardiovalve Ltd. Prosthetic heart valve with pouch
CN108760657B (zh) * 2018-05-31 2021-06-08 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 一种凝血酶检测方法及其试剂盒
US11028425B2 (en) 2018-06-08 2021-06-08 Glympse Bio, Inc. Diagnosis and monitoring of liver disease
US11732009B2 (en) 2018-06-08 2023-08-22 Glympse Bio, Inc. Activity sensor with tunable analyte
WO2023130146A2 (en) * 2022-01-03 2023-07-06 Nighthawk Biosciences, Inc. Cellular uptake peptide-therapeutic payload compositions and methods of use

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU689116B2 (en) * 1993-06-21 1998-03-26 Aventisub Ii Inc. Selectively cleavable linkers based on iminodiacetic acid ester bonds
DE10015797B4 (de) * 2000-03-26 2006-02-02 Bruker Daltonik Gmbh Multiplex-Analyse von DNA-Gemischen mittels photolytisch ablesbarer DNA-Chips
GB0523282D0 (en) * 2005-11-15 2005-12-21 Isis Innovation Methods using pores
US8734631B2 (en) * 2007-10-17 2014-05-27 Ohmx Corporation Chemistry used in biosensors
WO2010030716A1 (en) * 2008-09-10 2010-03-18 Igor Kutyavin Detection of nucleic acids by oligonucleotide probes cleaved in presence of endonuclease v
US9551703B2 (en) * 2009-08-04 2017-01-24 The Johns Hopkins University High precision quantitative assay composition and methods of use therefor
SG11201404892UA (en) * 2012-02-17 2014-09-26 Nvs Technologies Inc Polymer scaffolds for assay applications
US9670526B2 (en) * 2012-11-09 2017-06-06 Stratos Genomics, Inc. Concentrating a target molecule for sensing by a nanopore
ES2704902T3 (es) * 2013-05-06 2019-03-20 Two Pore Guys Inc Un método de detección de objetivos biológicos usando un nanoporo y un agente de unión a proteínas de fusión
US10597702B2 (en) * 2013-08-26 2020-03-24 Ontera Inc. Molecule detection using boronic acid substituted probes
CN104458813B (zh) * 2014-11-28 2016-08-31 中国科学院重庆绿色智能技术研究院 基于类金刚石薄膜的纳米孔测量系统及其制备方法
KR101945366B1 (ko) * 2015-03-11 2019-02-07 투 포어 가이즈, 인코포레이티드 경쟁 검정법을 통한 저분자의 나노포어 검출

Also Published As

Publication number Publication date
RU2017130853A3 (es) 2019-03-04
CN107209182A (zh) 2017-09-26
IL253382A0 (en) 2017-09-28
EP3254109A4 (en) 2018-07-04
EP3254109A1 (en) 2017-12-13
HK1244318A1 (zh) 2018-08-03
RU2017130853A (ru) 2019-03-04
CA2973729A1 (en) 2016-08-11
US20180023114A1 (en) 2018-01-25
JP2018503830A (ja) 2018-02-08
KR20170109046A (ko) 2017-09-27
RU2712245C2 (ru) 2020-01-27
AU2016215455A1 (en) 2017-08-17
WO2016126748A1 (en) 2016-08-11

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