MX2017002544A - Derivados de isoquinolinona utiles en el tratamiento contra el cancer. - Google Patents
Derivados de isoquinolinona utiles en el tratamiento contra el cancer.Info
- Publication number
- MX2017002544A MX2017002544A MX2017002544A MX2017002544A MX2017002544A MX 2017002544 A MX2017002544 A MX 2017002544A MX 2017002544 A MX2017002544 A MX 2017002544A MX 2017002544 A MX2017002544 A MX 2017002544A MX 2017002544 A MX2017002544 A MX 2017002544A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- treatment
- derivatives useful
- isoquinolinone derivatives
- compound
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- VDBNYAPERZTOOF-UHFFFAOYSA-N isoquinolin-1(2H)-one Chemical class C1=CC=C2C(=O)NC=CC2=C1 VDBNYAPERZTOOF-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14306352 | 2014-09-02 | ||
| PCT/EP2015/070082 WO2016034642A1 (en) | 2014-09-02 | 2015-09-02 | Isoquinolinone derivatives useful in the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2017002544A true MX2017002544A (es) | 2017-07-19 |
Family
ID=51494243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017002544A MX2017002544A (es) | 2014-09-02 | 2015-09-02 | Derivados de isoquinolinona utiles en el tratamiento contra el cancer. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9944641B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3189051A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2017525734A (cg-RX-API-DMAC7.html) |
| CN (1) | CN106795154B (cg-RX-API-DMAC7.html) |
| BR (1) | BR112017003651A2 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2017002544A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2690853C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016034642A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7061993B2 (ja) * | 2016-07-08 | 2022-05-02 | ライジェル ファーマシューティカルズ， インコーポレイテッド | チロシンキナーゼ阻害剤 |
| CN106699608A (zh) * | 2016-12-26 | 2017-05-24 | 常州大学 | 一种含有强吸电子基团的苯胍及其盐的制备方法 |
| CN111683976B (zh) | 2018-02-05 | 2022-11-18 | 生物辐射实验室股份有限公司 | 具有阴离子交换-疏水混合模式配体的色谱树脂 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO2783B1 (en) * | 2005-09-30 | 2014-03-15 | نوفارتيس ايه جي | Compounds 2-Amino-7, 8-dihydro-6H-Bayredo (3,4-D) Pyrimidine-5-Ones |
| EP2100894A1 (en) * | 2008-03-12 | 2009-09-16 | 4Sc Ag | Pyridopyrimidines used as Plk1 (polo-like kinase) inhibitors |
| US9029391B2 (en) | 2011-01-24 | 2015-05-12 | Viiv Healthcare Uk Limited | Isoquinoline compounds and methods for treating HIV |
| BR112014006643A2 (pt) * | 2011-09-20 | 2017-04-04 | Hoffmann La Roche | compostos de imidazopiridina, composições e métodos de uso dos mesmos |
| JP6128133B2 (ja) * | 2012-01-23 | 2017-05-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｉｇｆ−１ｒ／ｉｒ阻害剤としての５，８−ジヒドロ−６ｈ−ピラゾロ［３，４−ｈ］キナゾリン |
| US9718821B2 (en) * | 2012-02-23 | 2017-08-01 | Abbvie Inc. | Pyridopyrimidinone inhibitors of kinases |
| WO2014145909A2 (en) * | 2013-03-15 | 2014-09-18 | Dana-Farber Cancer Institute, Inc. | Pyrimido-diazepinone compounds and methods of treating disorders |
-
2015
- 2015-09-02 MX MX2017002544A patent/MX2017002544A/es unknown
- 2015-09-02 CN CN201580047253.7A patent/CN106795154B/zh not_active Expired - Fee Related
- 2015-09-02 RU RU2017108909A patent/RU2690853C2/ru not_active IP Right Cessation
- 2015-09-02 WO PCT/EP2015/070082 patent/WO2016034642A1/en not_active Ceased
- 2015-09-02 JP JP2017512003A patent/JP2017525734A/ja active Pending
- 2015-09-02 EP EP15762963.5A patent/EP3189051A1/en not_active Withdrawn
- 2015-09-02 BR BR112017003651A patent/BR112017003651A2/pt not_active IP Right Cessation
- 2015-09-02 US US15/507,941 patent/US9944641B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016034642A1 (en) | 2016-03-10 |
| JP2017525734A (ja) | 2017-09-07 |
| US20170240544A1 (en) | 2017-08-24 |
| CN106795154B (zh) | 2019-07-05 |
| RU2017108909A3 (cg-RX-API-DMAC7.html) | 2018-12-13 |
| BR112017003651A2 (pt) | 2017-12-05 |
| US9944641B2 (en) | 2018-04-17 |
| CN106795154A (zh) | 2017-05-31 |
| EP3189051A1 (en) | 2017-07-12 |
| RU2017108909A (ru) | 2018-10-03 |
| RU2690853C2 (ru) | 2019-06-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MD20170016A2 (ro) | Compuşi aminopirimidinici ca inhibitori JAK | |
| PH12017500281A1 (en) | Pyrrolopyrimidine compounds used as tlr7 agonist | |
| MA39986A (fr) | Dérivés de purine en tant qu'inhibiteurs de cd73 pour le traitement du cancer | |
| PH12016501898A1 (en) | Quinoxaline derivatives useful as fgfr kinase modulators | |
| EA033266B1 (ru) | Гидроксисложноэфирные производные, способ их получения и фармацевтические композиции, содержащие их | |
| MY176235A (en) | Compounds that inhibit mcl-1 protein | |
| MD20170070A2 (ro) | Derivaţi de chinazolină utilizaţi în tratamentul HIV | |
| MX2017008518A (es) | Compuestos de isoquinolina para el tratamiento de virus de inmunodeficiencia humana (vih). | |
| PH12016502378A1 (en) | Substituted dihydroisoquinolinone compounds | |
| PH12018500061A1 (en) | Oxysterols and methods of use thereof | |
| MD4684B1 (ro) | Formulări pe bază de imidazopirazine în calitate de inhibitori SYK | |
| EA201891063A1 (ru) | Производные дигидроимидазопиразинона, применимые в лечении рака | |
| MY194116A (en) | Pharmaceutical compounds | |
| TW201613864A (en) | Novel compounds | |
| MY181641A (en) | Amino pyran ring derivative and composition and use thereof | |
| MX2016003522A (es) | Derivados de quinazolinas y su uso como inhibidores de la adn metiltransferasa. | |
| TR201819805T4 (tr) | Flavaglin türevleri̇. | |
| PH12018500378B1 (en) | Novel annelated phenoxyacetamides | |
| MY178379A (en) | Naphthyridinedione derivatives as suppressors of non-sense mutations | |
| MX2017013099A (es) | Metodos para el tratamiento de trastornos inflamatorios. | |
| PH12016501997B1 (en) | Cycloalkyl-linked diheterocycle derivatives | |
| MX2017002544A (es) | Derivados de isoquinolinona utiles en el tratamiento contra el cancer. | |
| MX2017002627A (es) | Derivados de polieteres macrociclicos de n-aril-2-amino-4-aril-pir imidina como inhibidores de ftl3 y jak. | |
| PH12016502480A1 (en) | Compounds, pharmaceutical composition and their use in treating neurodegenerative diseases | |
| MX2017002747A (es) | Derivados de polieteres macrociclicos de n-aril-triciclopirimidin- 2-amino como inhibidores de ftl3 y jak. |