MX2016016295A - Metodos para tratar enfermedades cardiovasculares. - Google Patents
Metodos para tratar enfermedades cardiovasculares.Info
- Publication number
- MX2016016295A MX2016016295A MX2016016295A MX2016016295A MX2016016295A MX 2016016295 A MX2016016295 A MX 2016016295A MX 2016016295 A MX2016016295 A MX 2016016295A MX 2016016295 A MX2016016295 A MX 2016016295A MX 2016016295 A MX2016016295 A MX 2016016295A
- Authority
- MX
- Mexico
- Prior art keywords
- cardiovascular diseases
- methods
- heart
- treating
- ameliorating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/906—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7)
- G01N2333/90605—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4)
- G01N2333/90633—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3) in general
- G01N2333/90638—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3) in general with a definite EC number (1.4.3.-)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/326—Arrhythmias, e.g. ventricular fibrillation, tachycardia, atrioventricular block, torsade de pointes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Vascular Medicine (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Surgery (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
En el presente documento se proporcionan los métodos que se relacionan con una nueva estrategia terapéutica para el tratamiento de enfermedades cardiacas y/o cardiovasculares. El método incluye la administración de inhibidores de LOXL2 para tratar, prevenir, o mejorar al menos un síntoma asociado con las enfermedades cardiacas y/o cardiovasculares.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462010929P | 2014-06-11 | 2014-06-11 | |
PCT/US2015/034217 WO2015191362A1 (en) | 2014-06-11 | 2015-06-04 | Methods for treating cardiovascular diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016016295A true MX2016016295A (es) | 2017-03-31 |
Family
ID=53404947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016016295A MX2016016295A (es) | 2014-06-11 | 2015-06-04 | Metodos para tratar enfermedades cardiovasculares. |
Country Status (14)
Country | Link |
---|---|
US (2) | US20150361182A1 (es) |
EP (1) | EP3155016A1 (es) |
JP (1) | JP6353082B2 (es) |
KR (1) | KR20170018383A (es) |
CN (1) | CN106456772A (es) |
AR (1) | AR105752A1 (es) |
AU (2) | AU2015274987A1 (es) |
BR (1) | BR112016028750A2 (es) |
CA (1) | CA2951535A1 (es) |
EA (1) | EA201692202A1 (es) |
MX (1) | MX2016016295A (es) |
SG (1) | SG11201609522TA (es) |
TW (1) | TW201613639A (es) |
WO (1) | WO2015191362A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017031182A2 (en) * | 2015-08-17 | 2017-02-23 | Temple University Of The Commonwealth System Of Higher Education | Bag3 compositions and methods |
CN107596373A (zh) * | 2017-09-28 | 2018-01-19 | 韩庆亮 | 一种用于治疗心血管疾病的方法 |
US11679178B2 (en) | 2019-02-25 | 2023-06-20 | University Of Rochester | Methods for improving mechanical properties of a tissue or for regenerating an injured or diseased tissue |
IL266433B (en) * | 2019-05-02 | 2020-11-30 | Sagi Irit | Compositions comprising the propeptide of lysyl oxidase and uses thereof |
WO2021113401A2 (en) * | 2019-12-02 | 2021-06-10 | The Regents Of The University Of Colorado, A Body Corporate | Histone deacytlase 6 modulation of titin protein mediated cardiac tissue stiffness and method for same |
Family Cites Families (39)
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US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
US4965288A (en) | 1988-02-25 | 1990-10-23 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
US5021456A (en) | 1988-02-25 | 1991-06-04 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
US4943593A (en) | 1988-02-25 | 1990-07-24 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
US5252608A (en) | 1988-02-25 | 1993-10-12 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
US5182297A (en) | 1988-02-25 | 1993-01-26 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
US5059714A (en) | 1988-02-25 | 1991-10-22 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
US5120764A (en) | 1988-11-01 | 1992-06-09 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
US4997854A (en) | 1989-08-25 | 1991-03-05 | Trustees Of Boston University | Anti-fibrotic agents and methods for inhibiting the activity of lysyl oxidase in-situ using adjacently positioned diamine analogue substrates |
US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
US5279833A (en) | 1990-04-04 | 1994-01-18 | Yale University | Liposomal transfection of nucleic acids into animal cells |
US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
EP0546073B1 (en) | 1990-08-29 | 1997-09-10 | GenPharm International, Inc. | production and use of transgenic non-human animals capable of producing heterologous antibodies |
US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
GB9022788D0 (en) | 1990-10-19 | 1990-12-05 | Cortecs Ltd | Pharmaceutical formulations |
US5283185A (en) | 1991-08-28 | 1994-02-01 | University Of Tennessee Research Corporation | Method for delivering nucleic acids into cells |
DE69233528T2 (de) | 1991-11-25 | 2006-03-16 | Enzon, Inc. | Verfahren zur Herstellung von multivalenten antigenbindenden Proteinen |
US5908635A (en) | 1994-08-05 | 1999-06-01 | The United States Of America As Represented By The Department Of Health And Human Services | Method for the liposomal delivery of nucleic acids |
US6096716A (en) | 1994-12-12 | 2000-08-01 | The Board Of Regents, The University Of Texas System | Liposome-mediated transfection of central nervous system cells |
WO2001083702A2 (en) | 2000-05-03 | 2001-11-08 | University Of Hawaii | Novel members of the lysyl oxidases family of amine oxidases related applications |
WO2002061092A2 (en) * | 2001-01-29 | 2002-08-08 | Bayer Aktiengesellschaft | Regulation of human lysyl oxidase |
FR2828206B1 (fr) | 2001-08-03 | 2004-09-24 | Centre Nat Rech Scient | Utilisation d'inhibiteurs des lysyl oxydases pour la culture cellulaire et le genie tissulaire |
SI2185198T1 (sl) | 2007-08-02 | 2015-04-30 | Gilead Biologics, Inc. | Inhibitorji LOX in LOXL2 ter njihova uporaba |
JP6134142B2 (ja) | 2010-02-04 | 2017-05-24 | ギリアド バイオロジクス, インク.Gilead Biologics, Inc. | リシルオキシダーゼ様2(loxl2)に結合する抗体及びその使用方法 |
KR20140048156A (ko) * | 2011-06-01 | 2014-04-23 | 길리아드 바이오로직스, 인크. | 리실 옥시다제-유사 2 검정 및 그의 사용 방법 |
CN102868278B (zh) * | 2011-07-08 | 2017-05-10 | 德昌电机(深圳)有限公司 | 有刷电机及其转子 |
KR20150074179A (ko) * | 2012-10-30 | 2015-07-01 | 길리애드 사이언시즈, 인코포레이티드 | 리실 옥시다제-유사 2 (loxl2)와 관련된 치료 및 진단 방법 |
-
2015
- 2015-06-04 WO PCT/US2015/034217 patent/WO2015191362A1/en active Application Filing
- 2015-06-04 SG SG11201609522TA patent/SG11201609522TA/en unknown
- 2015-06-04 EP EP15729710.2A patent/EP3155016A1/en not_active Withdrawn
- 2015-06-04 CN CN201580031568.2A patent/CN106456772A/zh active Pending
- 2015-06-04 MX MX2016016295A patent/MX2016016295A/es unknown
- 2015-06-04 JP JP2016570098A patent/JP6353082B2/ja not_active Expired - Fee Related
- 2015-06-04 KR KR1020177000438A patent/KR20170018383A/ko active Search and Examination
- 2015-06-04 BR BR112016028750A patent/BR112016028750A2/pt not_active Application Discontinuation
- 2015-06-04 EA EA201692202A patent/EA201692202A1/ru unknown
- 2015-06-04 AU AU2015274987A patent/AU2015274987A1/en not_active Abandoned
- 2015-06-04 CA CA2951535A patent/CA2951535A1/en not_active Abandoned
- 2015-06-04 US US14/730,897 patent/US20150361182A1/en not_active Abandoned
- 2015-06-08 TW TW104118480A patent/TW201613639A/zh unknown
- 2015-06-10 AR ARP150101836A patent/AR105752A1/es unknown
-
2017
- 2017-10-19 US US15/788,604 patent/US20180155447A1/en not_active Abandoned
-
2018
- 2018-05-11 AU AU2018203309A patent/AU2018203309A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP6353082B2 (ja) | 2018-07-04 |
KR20170018383A (ko) | 2017-02-17 |
EA201692202A1 (ru) | 2017-06-30 |
SG11201609522TA (en) | 2016-12-29 |
CN106456772A (zh) | 2017-02-22 |
US20150361182A1 (en) | 2015-12-17 |
AU2015274987A1 (en) | 2016-11-24 |
TW201613639A (en) | 2016-04-16 |
BR112016028750A2 (pt) | 2017-11-14 |
CA2951535A1 (en) | 2015-12-17 |
AR105752A1 (es) | 2017-11-08 |
JP2017520534A (ja) | 2017-07-27 |
EP3155016A1 (en) | 2017-04-19 |
WO2015191362A1 (en) | 2015-12-17 |
AU2018203309A1 (en) | 2018-05-31 |
US20180155447A1 (en) | 2018-06-07 |
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