MX2016014166A - Compuestos de triaminopirimidina utiles para evitar o tratar la malaria. - Google Patents

Compuestos de triaminopirimidina utiles para evitar o tratar la malaria.

Info

Publication number
MX2016014166A
MX2016014166A MX2016014166A MX2016014166A MX2016014166A MX 2016014166 A MX2016014166 A MX 2016014166A MX 2016014166 A MX2016014166 A MX 2016014166A MX 2016014166 A MX2016014166 A MX 2016014166A MX 2016014166 A MX2016014166 A MX 2016014166A
Authority
MX
Mexico
Prior art keywords
triaminopirimidine
compounds
useful
avoid
treat malaria
Prior art date
Application number
MX2016014166A
Other languages
English (en)
Other versions
MX374458B (es
Inventor
Hameed Peer Mohamed Shahul
Patil Vikas
Murugan Kannan
Vithalrao Bellale Eknath
Raichurkar Anandkumar
LANDGE Sudhir
PUTTUR Jayashree
Roy CHOUDHURY Nilanjana
SHANBHAG Gajanan
Koushik Krishna
Iyer Pravin
Kirthika SAMBANDAMURTHY Vasan
Solapure Suresh
Narayanan Shridhar
Original Assignee
Medicines For Malaria Venture Mmv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicines For Malaria Venture Mmv filed Critical Medicines For Malaria Venture Mmv
Publication of MX2016014166A publication Critical patent/MX2016014166A/es
Publication of MX374458B publication Critical patent/MX374458B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se relaciona con triaminopirimidinas y con sales farmacéuticamente aceptables de las mismas, con su uso en el tratamiento o prevención de la malaria causada por especies de Plasmodium y con sus métodos de preparación.
MX2016014166A 2014-04-28 2015-03-26 Compuestos de triaminopirimidina útiles para evitar o tratar la malaria. MX374458B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2142CH2014 2014-04-28
PCT/EP2015/056496 WO2015165660A1 (en) 2014-04-28 2015-03-26 Triaminopyrimidine compounds useful for preventing or treating malaria

Publications (2)

Publication Number Publication Date
MX2016014166A true MX2016014166A (es) 2017-02-14
MX374458B MX374458B (es) 2025-03-06

Family

ID=52779638

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016014166A MX374458B (es) 2014-04-28 2015-03-26 Compuestos de triaminopirimidina útiles para evitar o tratar la malaria.

Country Status (22)

Country Link
US (1) US9957253B2 (es)
EP (1) EP3137455B1 (es)
JP (1) JP6529983B2 (es)
CN (1) CN106255685B (es)
AP (1) AP2016009570A0 (es)
BR (1) BR112016024467B1 (es)
CA (1) CA2946654C (es)
CY (1) CY1120700T1 (es)
DK (1) DK3137455T3 (es)
ES (1) ES2696350T3 (es)
HR (1) HRP20181816T1 (es)
HU (1) HUE042043T2 (es)
LT (1) LT3137455T (es)
MX (1) MX374458B (es)
MY (1) MY178971A (es)
PH (1) PH12016502322B1 (es)
PL (1) PL3137455T3 (es)
PT (1) PT3137455T (es)
RS (1) RS58124B1 (es)
SI (1) SI3137455T1 (es)
SM (1) SMT201800588T1 (es)
WO (1) WO2015165660A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105699584B (zh) * 2016-02-03 2018-02-09 昆药集团股份有限公司 一种蒿甲醚相关物质的检测方法
WO2018079629A1 (ja) 2016-10-26 2018-05-03 カルナバイオサイエンス株式会社 抗マラリア活性を有する新規ピリミジン誘導体
CN106727584A (zh) * 2017-02-08 2017-05-31 于贵庆 一种治疗骨病的药物组合物
CA3071226A1 (en) 2017-09-05 2019-03-14 Cadila Healthcare Limited A process for preparation of triaminopyrimidine compound and intermediates thereof
CN117327007B (zh) * 2023-09-26 2024-09-13 上海陶术生物科技有限公司 一种vt107的制备方法
WO2025115034A1 (en) * 2023-11-30 2025-06-05 Zydus Lifesciences Limited A process for the preparation of a triaminopyrimidine compound and novel intermediates thereof
EP4574143A1 (en) 2023-12-21 2025-06-25 Universität Regensburg Inhibitors of plasmodia remodeling enzymes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004037814A1 (en) * 2002-10-25 2004-05-06 Vertex Pharmaceuticals Incorporated Indazolinone compositions useful as kinase inhibitors
BRPI0516746A (pt) * 2004-09-30 2008-09-23 Tibotec Pharm Ltd 5-heterociclil pirimidinas para inibição de hiv
WO2014058685A1 (en) * 2012-10-08 2014-04-17 Merck Sharp & Dohme Corp. Inhibitors of irak4 activity

Also Published As

Publication number Publication date
US20170050951A1 (en) 2017-02-23
EP3137455A1 (en) 2017-03-08
CA2946654C (en) 2022-08-23
LT3137455T (lt) 2018-10-25
JP6529983B2 (ja) 2019-06-12
MY178971A (en) 2020-10-26
HUE042043T2 (hu) 2019-06-28
HK1231478A1 (en) 2017-12-22
ES2696350T3 (es) 2019-01-15
SI3137455T1 (sl) 2019-01-31
PH12016502322B1 (en) 2022-03-23
SMT201800588T1 (it) 2019-01-11
AP2016009570A0 (en) 2016-11-30
US9957253B2 (en) 2018-05-01
BR112016024467A2 (pt) 2017-08-15
PL3137455T3 (pl) 2019-01-31
EP3137455B1 (en) 2018-08-15
PT3137455T (pt) 2018-11-21
DK3137455T3 (en) 2018-12-10
CY1120700T1 (el) 2019-12-11
CA2946654A1 (en) 2015-11-05
CN106255685A (zh) 2016-12-21
CN106255685B (zh) 2019-08-20
PH12016502322A1 (en) 2017-01-30
WO2015165660A1 (en) 2015-11-05
RS58124B1 (sr) 2019-02-28
BR112016024467B1 (pt) 2022-11-29
JP2017514804A (ja) 2017-06-08
HRP20181816T1 (hr) 2018-12-28
MX374458B (es) 2025-03-06

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