MX2016013710A - Solucion oftalmica acuosa y metodo para tratar el sindrome del ojo seco. - Google Patents
Solucion oftalmica acuosa y metodo para tratar el sindrome del ojo seco.Info
- Publication number
- MX2016013710A MX2016013710A MX2016013710A MX2016013710A MX2016013710A MX 2016013710 A MX2016013710 A MX 2016013710A MX 2016013710 A MX2016013710 A MX 2016013710A MX 2016013710 A MX2016013710 A MX 2016013710A MX 2016013710 A MX2016013710 A MX 2016013710A
- Authority
- MX
- Mexico
- Prior art keywords
- dry eye
- ophthalmic solution
- eye syndrome
- aqueous ophthalmic
- treating dry
- Prior art date
Links
- 208000003556 Dry Eye Syndromes Diseases 0.000 title abstract 3
- 206010013774 Dry eye Diseases 0.000 title abstract 3
- 229940054534 ophthalmic solution Drugs 0.000 title abstract 3
- 239000002997 ophthalmic solution Substances 0.000 title abstract 3
- 229920001661 Chitosan Polymers 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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- A61K9/0048—Eye, e.g. artificial tears
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- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
-
- A—HUMAN NECESSITIES
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- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
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Abstract
La presente invención se refiere a una solución oftálmica acuosa estéril que comprende de aproximadamente 0,05% a aproximadamente 0,5% (peso/peso) de N-(N5 acetilcisteinil)quitosano o una de sus sales farmacéuticamente aceptables en una solución portadora, en donde el N-(N-acetilcisteinil)quitosano tiene un contenido de grupos tiol libres en una cantidad de 80 µmol/g de polímero a 280 µmol/g de polímero. La invención también se refiere a un contenedor que contiene la solución oftálmica, así como también al uso de ésta en la prevención o tratamiento del síndrome del ojo seco o de los signos y/o síntomas de ojos secos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14167381 | 2014-05-07 | ||
PCT/EP2015/059674 WO2015169728A1 (en) | 2014-05-07 | 2015-05-04 | Aqueous ophthalmic solution and method for treating dry eye syndrome |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016013710A true MX2016013710A (es) | 2017-03-31 |
Family
ID=50693490
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016013710A MX2016013710A (es) | 2014-05-07 | 2015-05-04 | Solucion oftalmica acuosa y metodo para tratar el sindrome del ojo seco. |
Country Status (27)
Country | Link |
---|---|
US (2) | US10342759B2 (es) |
EP (1) | EP3139903B1 (es) |
JP (1) | JP6639480B2 (es) |
KR (1) | KR102378391B1 (es) |
CN (1) | CN106456536B (es) |
AR (1) | AR100334A1 (es) |
AU (1) | AU2015257874B2 (es) |
BR (1) | BR112016024454B1 (es) |
CA (1) | CA2947065C (es) |
CL (1) | CL2016002815A1 (es) |
CY (1) | CY1122122T1 (es) |
DK (1) | DK3139903T3 (es) |
ES (1) | ES2747808T3 (es) |
HR (1) | HRP20191667T1 (es) |
HU (1) | HUE046425T2 (es) |
IL (1) | IL248804B (es) |
LT (1) | LT3139903T (es) |
MA (1) | MA39767B1 (es) |
ME (1) | ME03505B (es) |
MX (1) | MX2016013710A (es) |
PL (1) | PL3139903T3 (es) |
PT (1) | PT3139903T (es) |
RS (1) | RS59383B1 (es) |
RU (1) | RU2688935C2 (es) |
SG (1) | SG11201608402WA (es) |
SI (1) | SI3139903T1 (es) |
WO (1) | WO2015169728A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY181959A (en) | 2014-05-07 | 2021-01-15 | Bristol Myers Squibb Co | Pyrrolidine gpr40 modulators for the treatment of diseases such as diabetes |
US9463201B2 (en) | 2014-10-19 | 2016-10-11 | M.G. Therapeutics Ltd | Compositions and methods for the treatment of meibomian gland dysfunction |
FR3039765B1 (fr) * | 2015-08-07 | 2018-08-24 | Oreal | Procede cosmetique de traitement des matieres keratiniques |
US10688122B2 (en) | 2015-09-28 | 2020-06-23 | Azura Ophthalmics Ltd. | Thiol and disulfide-containing agents for increasing meibomian gland lipid secretion |
KR20180066104A (ko) | 2015-10-30 | 2018-06-18 | 크로마-파르마 게젤샤프트 엠.베.하. | 무균 수성 안과용 액제의 치료적 용도 |
KR20180066240A (ko) | 2015-10-30 | 2018-06-18 | 크로마-파르마 게젤샤프트 엠.베.하. | 무균 수성 안과용 액제의 치료적 용도 |
US10391119B2 (en) * | 2015-12-22 | 2019-08-27 | Nof Corporation | Lacrimal oily layer stabilizer and eye drops comprising same |
CN109310665A (zh) | 2016-04-14 | 2019-02-05 | 阿祖拉眼科有限公司 | 用于治疗睑板腺功能障碍的二硫化硒组合物 |
ES2650981B2 (es) | 2016-07-20 | 2018-05-04 | Ocupharm Diagnostics, Sl | Preparación y uso de un extracto de Artemia salina para tratar la superficie ocular |
US10618986B2 (en) * | 2016-10-19 | 2020-04-14 | Alcon Inc. | Hydrophilic copolymer with pendant thiol groups |
AR110125A1 (es) * | 2016-11-07 | 2019-02-27 | Croma Pharma Ges M B H | Compuestos poliméricos que liberan sulfuro de hidrógeno |
ES2669446B1 (es) * | 2016-11-24 | 2019-03-13 | Saiz Manuel Munoz | Producto oftálmico |
KR102541236B1 (ko) * | 2017-03-29 | 2023-06-08 | 아주라 오프탈믹스 엘티디 | 마이봄샘 지질 분비 증가를 위한 작용제 |
WO2018202783A1 (en) | 2017-05-03 | 2018-11-08 | Croma-Pharma Gmbh | Sterile aqueous ophthalmic solution containing n-(n-acetylcysteinyl)-chitosan for treating non-infectious corneal disorders |
TWI833406B (zh) | 2018-02-28 | 2024-02-21 | 日商參天製藥股份有限公司 | 含有迪夸弗索(Diquafosol)及陽離子性聚合物之眼科用組合物 |
CN109793707B (zh) * | 2019-01-30 | 2022-04-08 | 温州医科大学 | 一种透明质酸—n-乙酰半胱氨酸—壳聚糖滴眼液及其制备方法 |
TW202122094A (zh) * | 2019-08-27 | 2021-06-16 | 日商參天製藥股份有限公司 | 含有迪夸弗索(diquafosol)或其鹽、及聚乙烯吡咯烷酮之水性眼科用組合物 |
US20210145861A1 (en) * | 2019-11-18 | 2021-05-20 | Gregory J. PAMEL | Chitosan containing compositions and methods relating to same |
EP4087655A4 (en) | 2020-01-10 | 2024-02-21 | Azura Ophthalmics Ltd | INSTRUCTIONS FOR COMPOSITION AND SENSITIVITY |
CN114848670B (zh) * | 2022-05-26 | 2023-06-02 | 青岛博益特生物材料股份有限公司 | 一种滴眼液及其制备方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
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IT1258781B (it) | 1992-01-16 | 1996-02-29 | Zambon Spa | Composizione farmaceutica oftalmica contenente n-acetilcisteina e polivinilalcol |
FR2692582B1 (fr) | 1992-06-18 | 1998-09-18 | Flamel Tech Sa | Nouveaux derives reticulables de collagene, leur procede d'obtention et leur application a la preparation de biomateriaux. |
AU5015296A (en) * | 1995-04-04 | 1996-10-23 | Otsuka Pharmaceutical Co., Ltd. | Package holding a procaterol hydrochloride aqueous solution formulation, and a procaterol hydrochloride aqueous solution formulation |
EP0938896A1 (en) * | 1998-01-15 | 1999-09-01 | Novartis AG | Autoclavable pharmaceutical compositions containing a chelating agent |
AT406054B (de) * | 1998-11-04 | 2000-02-25 | Andreas Bernkop-Schnuerch | Verfahren zur verbesserung der mucoadhäsion von polymeren sowie deren herstellung und verwendung |
JP2000302803A (ja) | 1999-04-22 | 2000-10-31 | Noevir Co Ltd | アミノ酸及びペプチドにより遊離アミノ基が選択的に置換され、実質的に水酸基の置換のない部分脱アセチル化キチン・キトサン誘導体、及びその製造方法 |
ITRM20010438A1 (it) * | 2001-07-23 | 2003-01-23 | Farmigea Spa | Preparato oftalmico a base di n-acetilcisteina per il trattamento della sindrome dell'occhio secco. |
US20080093247A1 (en) * | 2006-10-24 | 2008-04-24 | Alcon Manufacturing Ltd. | Packaging materials for formulations containing 2-pyrrolidone derivatives |
ATE545436T1 (de) * | 2006-12-22 | 2012-03-15 | Croma Pharma Ges M B H | Verwendung von thiolierten polysacchariden zum gewebeaufbau |
JP5541926B2 (ja) | 2007-01-31 | 2014-07-09 | アラーガン、インコーポレイテッド | 眼薬物送達用の新規生体材料ならびにその製造および使用方法 |
US9452592B2 (en) | 2007-08-28 | 2016-09-27 | Cryovac, Inc. | Multilayer film having an active oxygen barrier layer with radiation enhanced active barrier properties |
CN102159220A (zh) | 2008-04-24 | 2011-08-17 | 麦德托尼克公司 | 硫醇化的壳聚糖凝胶 |
AU2009240513B2 (en) | 2008-04-24 | 2015-03-26 | Medtronic, Inc. | Chitosan-containing protective composition |
AU2009240512B2 (en) | 2008-04-24 | 2014-07-10 | Medtronic, Inc. | Protective gel based on chitosan and oxidized polysaccharide |
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2015
- 2015-05-04 PT PT157189564T patent/PT3139903T/pt unknown
- 2015-05-04 CA CA2947065A patent/CA2947065C/en active Active
- 2015-05-04 MX MX2016013710A patent/MX2016013710A/es active IP Right Grant
- 2015-05-04 AU AU2015257874A patent/AU2015257874B2/en active Active
- 2015-05-04 LT LTEP15718956.4T patent/LT3139903T/lt unknown
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