MX2016005333A - Método para tratar la hemofilia induciendo tolerancia a factores sanguíneos. - Google Patents

Método para tratar la hemofilia induciendo tolerancia a factores sanguíneos.

Info

Publication number
MX2016005333A
MX2016005333A MX2016005333A MX2016005333A MX2016005333A MX 2016005333 A MX2016005333 A MX 2016005333A MX 2016005333 A MX2016005333 A MX 2016005333A MX 2016005333 A MX2016005333 A MX 2016005333A MX 2016005333 A MX2016005333 A MX 2016005333A
Authority
MX
Mexico
Prior art keywords
haemophilia
inducing tolerance
blood factors
relates
treating haemophilia
Prior art date
Application number
MX2016005333A
Other languages
English (en)
Inventor
Locroix-Desmazes Sébastien
Mondoulet Lucie
DIOSZEGHY Vincent
Original Assignee
Dbv Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dbv Tech filed Critical Dbv Tech
Publication of MX2016005333A publication Critical patent/MX2016005333A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches

Abstract

La presente invención se refiere al tratamiento de la hemofilia. Más específicamente, la invención se refiere a un nuevo método para inducir una tolerancia inmunitaria frente al menos un factor sanguíneo usado para tratar la hemofilia a través de la ruta epicutánea mediante la aplicación de un dispositivo de parche cutáneo que comprende un factor sanguíneo para continuar el tratamiento de la hemofilia. La presente invención también se refiere un dispositivo de parche cutáneo que contiene factor VIII.
MX2016005333A 2013-10-22 2014-10-21 Método para tratar la hemofilia induciendo tolerancia a factores sanguíneos. MX2016005333A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13306453 2013-10-22
PCT/EP2014/072508 WO2015059121A1 (en) 2013-10-22 2014-10-21 Method of treating haemophilia by inducing tolerance to blood factors

Publications (1)

Publication Number Publication Date
MX2016005333A true MX2016005333A (es) 2017-02-15

Family

ID=49513880

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016005333A MX2016005333A (es) 2013-10-22 2014-10-21 Método para tratar la hemofilia induciendo tolerancia a factores sanguíneos.

Country Status (12)

Country Link
US (1) US20160220644A1 (es)
EP (1) EP3060242A1 (es)
JP (1) JP2016534083A (es)
KR (1) KR20160090810A (es)
CN (1) CN105848670A (es)
AU (1) AU2014339034A1 (es)
BR (1) BR112016009064A2 (es)
CA (1) CA2928314A1 (es)
EA (1) EA201690817A1 (es)
IL (1) IL245285A0 (es)
MX (1) MX2016005333A (es)
WO (1) WO2015059121A1 (es)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5560922A (en) * 1986-05-30 1996-10-01 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process
SE465222C5 (sv) 1989-12-15 1998-02-10 Pharmacia & Upjohn Ab Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning
GB2267435A (en) * 1992-06-01 1993-12-08 British Tech Group Factor VIII
US6458563B1 (en) 1996-06-26 2002-10-01 Emory University Modified factor VIII
WO2002060917A2 (en) * 2000-12-01 2002-08-08 Regents Of The University Of Minnesota Method to treat hemophilia
FR2822049B1 (fr) 2001-03-13 2003-08-01 Dbv Medica 1 Patch destine notamment a depister l'etat de sensibilisation d'un sujet a un allergene, procede de fabrication et utilisation
US7635488B2 (en) 2001-03-13 2009-12-22 Dbv Technologies Patches and uses thereof
WO2006003183A1 (de) 2004-07-02 2006-01-12 Alois Jungbauer Peptide zur blockierung von fviii-inhibitoren
ES2821832T3 (es) * 2004-11-12 2021-04-27 Bayer Healthcare Llc Modificación de FVIII dirigida al sitio
US8071545B2 (en) * 2005-03-15 2011-12-06 Lewis S. Coleman, Md, Inc. Therapies and compositions for controlling the stress mechanism and for stabilizing hemostasis in an organism
EP1985631A1 (en) 2007-04-20 2008-10-29 LFB Biotechnologies Demannosylated recombinant factor VIII for the treatment of patients with hemophiila A
FR2921562B1 (fr) 2007-10-01 2012-06-15 Dbv Tech Dispositif adhesif pour application cutanee
WO2009058446A1 (en) * 2007-11-01 2009-05-07 University Of Rochester Recombinant factor viii having increased stability
FR2926466B1 (fr) 2008-01-23 2010-11-12 Dbv Tech Procede de fabrication de patchs par electrospray
GB0801513D0 (en) * 2008-01-28 2008-03-05 Circassia Ltd Peptides from factor VIII

Also Published As

Publication number Publication date
AU2014339034A1 (en) 2016-05-19
IL245285A0 (en) 2016-06-30
JP2016534083A (ja) 2016-11-04
BR112016009064A2 (pt) 2017-09-19
EA201690817A1 (ru) 2016-08-31
CA2928314A1 (en) 2015-04-30
EP3060242A1 (en) 2016-08-31
CN105848670A (zh) 2016-08-10
WO2015059121A1 (en) 2015-04-30
KR20160090810A (ko) 2016-08-01
US20160220644A1 (en) 2016-08-04

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