MX2016004316A - Inhalador de polvo seco. - Google Patents

Inhalador de polvo seco.

Info

Publication number
MX2016004316A
MX2016004316A MX2016004316A MX2016004316A MX2016004316A MX 2016004316 A MX2016004316 A MX 2016004316A MX 2016004316 A MX2016004316 A MX 2016004316A MX 2016004316 A MX2016004316 A MX 2016004316A MX 2016004316 A MX2016004316 A MX 2016004316A
Authority
MX
Mexico
Prior art keywords
dose
dry powder
patient
powder inhaler
salmeterol
Prior art date
Application number
MX2016004316A
Other languages
English (en)
Inventor
Dalvi Mukul
Kee Tee Seah
Original Assignee
Teva Branded Pharmaceutical Products R&D Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51743574&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2016004316(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Branded Pharmaceutical Products R&D Inc filed Critical Teva Branded Pharmaceutical Products R&D Inc
Publication of MX2016004316A publication Critical patent/MX2016004316A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0076—Mechanical counters having a display or indicator on a drum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0078—Mechanical counters having a display or indicator on a strip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Abstract

Esta invención proporciona un inhalador de polvo seco que comprende: un medicamento en polvo seco que comprende propionato de fluticasona, xinafoato de salmeterol y un vehículo de lactosa; en donde, la dosis suministrada de salmeterol por accionamiento es menor a 50 µg; y en donde la dosis proporciona un FEV1 ajustado al valor inicial en un paciente de más de 150 mL dentro de los 30 minutos de haber recibido la dosis. Un método de tratamiento de un paciente incluye la administración a un paciente de un medicamento en polvo seco que tiene propionato de fluticasona, xinafoato de salmeterol y un vehículo de lactosa; en donde, la dosis suministrada de salmeterol por accionamiento es menor a 50 µg; y en donde la dosis proporciona un FEV1 ajustado al valor inicial en un paciente de más de 150 mL dentro de los 30 minutos de haber recibido la dosis.
MX2016004316A 2013-10-07 2014-10-06 Inhalador de polvo seco. MX2016004316A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361887589P 2013-10-07 2013-10-07
US201361888301P 2013-10-08 2013-10-08
PCT/US2014/059285 WO2015054124A2 (en) 2013-10-07 2014-10-06 Dry powder inhaler

Publications (1)

Publication Number Publication Date
MX2016004316A true MX2016004316A (es) 2016-10-12

Family

ID=51743574

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016004316A MX2016004316A (es) 2013-10-07 2014-10-06 Inhalador de polvo seco.

Country Status (23)

Country Link
US (2) US20160243320A1 (es)
EP (1) EP3054920B1 (es)
JP (1) JP6543620B2 (es)
KR (1) KR102364945B1 (es)
CN (1) CN105636630B (es)
AU (1) AU2014332191B2 (es)
BR (1) BR112016007771B1 (es)
CA (1) CA2926432A1 (es)
CL (1) CL2016000735A1 (es)
DK (1) DK3054920T3 (es)
EA (1) EA035329B1 (es)
ES (1) ES2863198T3 (es)
HK (2) HK1219444A1 (es)
HU (1) HUE055042T2 (es)
IL (1) IL244959B (es)
MX (1) MX2016004316A (es)
PE (1) PE20160543A1 (es)
PH (1) PH12016500619A1 (es)
PL (1) PL3054920T3 (es)
PT (1) PT3054920T (es)
TW (1) TWI673070B (es)
WO (1) WO2015054124A2 (es)
ZA (1) ZA201601960B (es)

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CA2846899C (en) 2011-09-07 2019-12-03 Syphase, Llc Dry powder inhalation device
MX2016004316A (es) * 2013-10-07 2016-10-12 Teva Branded Pharmaceutical Products R&D Inc Inhalador de polvo seco.
AU356104S (en) * 2013-11-29 2014-06-24 Norton Waterford Ltd Respiratory apparatus
AU356105S (en) * 2013-11-29 2014-06-24 Norton Waterford Ltd Respiratory apparatus
USD752734S1 (en) 2014-03-10 2016-03-29 Civitas Therapeutics, Inc. Inhaler grip
USD752204S1 (en) * 2014-03-10 2016-03-22 Civitas Therapeutics, Inc. Indicator for an inhaler
USD755367S1 (en) * 2014-03-10 2016-05-03 Civitas Therapeutics, Inc. Indicator for an inhaler
MA41378A (fr) * 2015-01-20 2017-11-28 Teva Branded Pharmaceutical Prod R & D Inc Inhalateur de poudre sèche comprenant du propionate de fluticasone et du xinafoate de salmétérol
CN107095875B (zh) * 2016-02-23 2022-03-18 天津金耀集团有限公司 一种昔奈酸沙美特罗丙酸氟替卡松复方粉吸入剂组合物
JP7231410B2 (ja) * 2016-04-12 2023-03-01 バイオコープ プロダクション エス．アー． 定量吸入器用アドオン装置、遵守向上システム、及び定量吸入器における使用の遵守向上のための方法
CN106267484A (zh) * 2016-08-08 2017-01-04 中山市美捷时包装制品有限公司 一种干粉吸入装置的定量供料机构
USD832997S1 (en) * 2016-10-21 2018-11-06 Norton (Waterford) Limited Inhaler
USD832998S1 (en) * 2016-10-21 2018-11-06 Norton (Waterford) Limited Inhaler
USD852947S1 (en) * 2016-10-21 2019-07-02 Norton (Waterford) Limited Inhaler
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USD853555S1 (en) * 2017-01-03 2019-07-09 Norton (Waterford) Limited Inhaler
GB201700727D0 (en) * 2017-01-16 2017-03-01 Teva Pharma Inhalers and airflow adaptors therefor
AU2018244582A1 (en) 2017-03-28 2019-09-19 Concentrx Pharmaceuticals, Inc. Devices and methods for delivering dry powder medicaments
CN107737393B (zh) * 2017-10-12 2020-08-28 上海新黄河制药有限公司 一种用于粉雾剂吸入装置的制剂雾化流道
CN107715264B (zh) * 2017-10-12 2021-01-29 上海新黄河制药有限公司 一种粉雾剂装置制剂粉末团聚物的分散/解聚装置
BR112020011285A2 (pt) 2017-12-13 2020-11-24 Emphasys Importadora Exportadora E Distribuidora Ltda. inalador de pó seco
USD948704S1 (en) * 2019-07-26 2022-04-12 Lupin Ltd. Inhaler
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USD949324S1 (en) * 2019-07-26 2022-04-19 Lupin Ltd. Inhaler
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GB202012742D0 (en) * 2020-08-14 2020-09-30 Norton Waterford Ltd An inhalable medicament
EP4196105A1 (en) 2020-08-14 2023-06-21 Norton (Waterford) Limited An inhalable formulation of fluticasone propionate and albuterol sulfate

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Also Published As

Publication number Publication date
TW201542252A (zh) 2015-11-16
HUE055042T2 (hu) 2021-10-28
EA035329B1 (ru) 2020-05-28
CL2016000735A1 (es) 2016-11-11
US9066957B2 (en) 2015-06-30
KR20160065204A (ko) 2016-06-08
EP3054920A2 (en) 2016-08-17
CN105636630B (zh) 2020-05-19
TWI673070B (zh) 2019-10-01
AU2014332191A1 (en) 2016-04-21
PT3054920T (pt) 2021-03-23
PL3054920T3 (pl) 2021-07-05
WO2015054124A3 (en) 2015-09-03
CN105636630A (zh) 2016-06-01
KR102364945B1 (ko) 2022-02-17
HK1222127A1 (zh) 2017-06-23
BR112016007771A2 (es) 2017-08-01
IL244959A0 (en) 2016-05-31
PH12016500619B1 (en) 2016-06-13
ES2863198T3 (es) 2021-10-08
CA2926432A1 (en) 2015-04-16
JP2016536043A (ja) 2016-11-24
DK3054920T3 (da) 2021-03-29
EA201690738A1 (ru) 2016-08-31
PE20160543A1 (es) 2016-06-05
EP3054920B1 (en) 2021-03-03
US20160243320A1 (en) 2016-08-25
AU2014332191B2 (en) 2020-04-02
HK1219444A1 (zh) 2017-04-07
ZA201601960B (en) 2017-08-30
NZ718315A (en) 2021-10-29
BR112016007771B1 (pt) 2023-03-28
IL244959B (en) 2020-11-30
JP6543620B2 (ja) 2019-07-10
PH12016500619A1 (en) 2016-06-13
WO2015054124A2 (en) 2015-04-16
US20150099726A1 (en) 2015-04-09

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