MX2016002911A - Composiciones y metodos para evaluar el rechazo agudo en el trasplante renal. - Google Patents

Composiciones y metodos para evaluar el rechazo agudo en el trasplante renal.

Info

Publication number
MX2016002911A
MX2016002911A MX2016002911A MX2016002911A MX2016002911A MX 2016002911 A MX2016002911 A MX 2016002911A MX 2016002911 A MX2016002911 A MX 2016002911A MX 2016002911 A MX2016002911 A MX 2016002911A MX 2016002911 A MX2016002911 A MX 2016002911A
Authority
MX
Mexico
Prior art keywords
compositions
methods
acute rejection
renal transplantation
assessing acute
Prior art date
Application number
MX2016002911A
Other languages
English (en)
Inventor
Minnie M Sarwal
Original Assignee
Immucor Gti Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immucor Gti Diagnostics Inc filed Critical Immucor Gti Diagnostics Inc
Publication of MX2016002911A publication Critical patent/MX2016002911A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se proporcionan en la presente métodos, composiciones y kits para diagnosticar rechazo agudo de trasplantes renales usando el perfil de expresión genética de conjuntos de genes clasificadores; tales métodos y composiciones son independientes de factores de confusión externos como edad del receptor, centro de trasplante, fuente de ARN, ensayo, causa de enfermedad renal de etapa terminal, co-morbilidades, uso de inmunosupresión y similares.
MX2016002911A 2013-09-06 2014-09-05 Composiciones y metodos para evaluar el rechazo agudo en el trasplante renal. MX2016002911A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361874970P 2013-09-06 2013-09-06
US201461987342P 2014-05-01 2014-05-01
PCT/US2014/054342 WO2015035203A1 (en) 2013-09-06 2014-09-05 Compositions and methods for assessing acute rejection in renal transplantation

Publications (1)

Publication Number Publication Date
MX2016002911A true MX2016002911A (es) 2017-02-17

Family

ID=52628968

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016002911A MX2016002911A (es) 2013-09-06 2014-09-05 Composiciones y metodos para evaluar el rechazo agudo en el trasplante renal.

Country Status (9)

Country Link
US (2) US20160348174A1 (es)
EP (1) EP3041959A4 (es)
JP (3) JP2016531580A (es)
CN (1) CN106062208A (es)
AU (1) AU2014318005B2 (es)
BR (1) BR112016004515A8 (es)
CA (2) CA2922749A1 (es)
MX (1) MX2016002911A (es)
WO (1) WO2015035203A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015035367A1 (en) * 2013-09-09 2015-03-12 The Scripps Research Institute Methods and systems for analysis of organ transplantation
US11104951B2 (en) 2014-05-22 2021-08-31 The Scripps Research Institute Molecular signatures for distinguishing liver transplant rejections or injuries
US20200174014A1 (en) 2016-12-19 2020-06-04 Osaka University METHOD FOR IN VITRO EARLY DIAGNOSIS OF ANTIBODY MEDIATED REJECTION AFTER ORGAN TRANSPLANTATION USING IgM-TYPE MEMORY B CELL DIFFERENTIATION CULTURE SYSTEM
EP3790987A4 (en) * 2018-05-10 2022-01-19 The Scripps Research Institute GENOME-WIDE CLASSIFIERS FOR DETECTING SUBACUTE GRAFT REJECTION AND OTHER TRANSPLANTATION CONDITIONS
FR3082524B1 (fr) * 2018-06-18 2022-03-25 Univ Paris Sud Methode de stratification du risque de nephropathie a bk-virus apres transplantation renale
CA3136684A1 (en) * 2019-05-06 2020-11-12 The Regents Of The University Of California Non-hla markers of transplant rejection
US20240027476A1 (en) 2020-09-08 2024-01-25 Sekisui Medical Co., Ltd. Blood coagulation reaction analysis method
CN116472354A (zh) 2020-10-29 2023-07-21 积水医疗株式会社 凝血反应的检测方法
WO2022186381A1 (ja) 2021-03-05 2022-09-09 積水メディカル株式会社 凝固時間延長要因の推定方法
CN113380368A (zh) * 2021-06-22 2021-09-10 四川省人民医院 一种用于肾移植受者的术后监测装置
WO2023034292A1 (en) * 2021-08-30 2023-03-09 University Of Maryland, Baltimore Methods of predicting long-term outcome in kidney transplant patients using pre-transplantation kidney transcriptomes
CN117881968A (zh) 2021-08-31 2024-04-12 积水医疗株式会社 凝血反应异常的检测方法
CN115394376B (zh) * 2022-09-28 2023-04-18 奥明(杭州)生物医药有限公司 一种预测环状rna ires的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2492498T3 (es) * 2009-01-15 2014-09-09 The Board Of Trustees Of The Leland Stanford Junior University Panel de biomarcadores para el diagnóstico y la predicción de rechazo de injerto
EP2550371A4 (en) * 2010-03-25 2013-11-20 Univ Leland Stanford Junior PROTEIN AND GENE BIOMARKERS FOR EXTRACTING ORGAN TRANSPLANTS
GB201021149D0 (en) * 2010-12-14 2011-01-26 Georg August Uni Gottingen Stiftung Offentlichen Rechts Use of a skin explant assay for mRNA expression analysis for the identification of new genes and drug targets associated with graft versus host disease

Also Published As

Publication number Publication date
AU2014318005A1 (en) 2016-04-07
CA2922749A1 (en) 2015-03-12
CA3184317A1 (en) 2015-03-12
EP3041959A1 (en) 2016-07-13
CN106062208A (zh) 2016-10-26
WO2015035203A1 (en) 2015-03-12
JP2022177115A (ja) 2022-11-30
US20210207218A1 (en) 2021-07-08
US20160348174A1 (en) 2016-12-01
JP2016531580A (ja) 2016-10-13
BR112016004515A8 (pt) 2020-02-11
JP2020039344A (ja) 2020-03-19
EP3041959A4 (en) 2017-03-15
AU2014318005B2 (en) 2020-09-10
JP7228499B2 (ja) 2023-02-24

Similar Documents

Publication Publication Date Title
MX2016002911A (es) Composiciones y metodos para evaluar el rechazo agudo en el trasplante renal.
MX2021002826A (es) Nuevo formato biespecifico adecuado para uso en tamizado de alto rendimiento.
WO2016057951A3 (en) Crispr oligonucleotides and gene editing
SG10201810723VA (en) Improved t cell compositions
WO2014172046A3 (en) Gene fusions and gene variants associated with cancer
GB201710984D0 (en) Cells, vertebrates, populations & methods
WO2016161169A3 (en) Cell culture incubators with integrated cell manipulation systems
WO2011156654A3 (en) Pathways characterization of cells
GB2511221A (en) Methods and compositions for classification of samples
WO2015149034A3 (en) Gene fusions and gene variants associated with cancer
WO2013188469A3 (en) Pathways characterization of cells
MX2013012920A (es) Composiciones que comprenden particulas de hidrogel.
MY183188A (en) Non-human animals having a humanized b-cell activating factor gene
MX2016006513A (es) Animales no humanos que tienen un gen humanizado de un ligando inductor de la proliferacion.
MX366112B (es) Medio de cultivo celular y metodos de produccion de anticuerpos.
DK2257301T3 (da) Immunterapi baseret på allogene cancerceller.
WO2014145870A3 (en) Novel compositions, methods and kits for blood typing
WO2012136909A3 (fr) HYDROGELS THIXOTROPES À BASE α-LACTALBUMINE, LEUR PROCÉDÉ DE PRÉPARATION ET LEURS UTILISATIONS
WO2012112958A3 (en) High-throughput assays to probe leukemia within the stromal niche
MX2022000516A (es) Metodos relacionados con celulas pluripotentes.
EA201791233A1 (ru) Материал стволовых клеток и способ его получения
WO2012054935A3 (en) Formation of hematopoietic progenitor cells from mesenchymal stem cells
WO2012175745A9 (en) Cell secreted proteins for the treatment of myocardial infarction
MX2017014890A (es) Metodos de produccion de acetolactato-descarboxilasa (aldc).
WO2015175534A3 (en) Compositions and methods employing stem cell-derived cardiomyocytes