MX2016000811A - Amdinocilina para la rápida determinación de la susceptibilidad a antibióticos beta-lactámicos. - Google Patents

Amdinocilina para la rápida determinación de la susceptibilidad a antibióticos beta-lactámicos.

Info

Publication number
MX2016000811A
MX2016000811A MX2016000811A MX2016000811A MX2016000811A MX 2016000811 A MX2016000811 A MX 2016000811A MX 2016000811 A MX2016000811 A MX 2016000811A MX 2016000811 A MX2016000811 A MX 2016000811A MX 2016000811 A MX2016000811 A MX 2016000811A
Authority
MX
Mexico
Prior art keywords
susceptibility
ribosomal rna
amdinocillin
antibiotics
antibiotic
Prior art date
Application number
MX2016000811A
Other languages
English (en)
Inventor
Haake David
HALFORD Colin
M Churchill Bernard
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of MX2016000811A publication Critical patent/MX2016000811A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Se describen métodos para detectar la susceptibilidad de un espécimen a los antibióticos, y en particular para la mejora de tales pruebas de susceptibilidad a los antibióticos betalactámicos y antibióticos que se unen a las proteínas de unión a penicilina. El método comprende poner en contacto la muestra con una sonda de oligonucleótido que hibrida específicamente con un ácido nucleico destino región de la secuencia de ARN ribosómico. La secuencia destino es ARN ribosómico maduro o en el sitio de empalme entre una cola de ARN pre-ribosómico ARN ribosómico y maduro. La realización del procedimiento en presencia y ausencia de una determinación de la susceptibilidad a los antibióticos permisos antibiótico Las pruebas de sensibilidad rápida está activada por la adición de la PBP2 antibiótico específico, amdinocilina.
MX2016000811A 2013-07-23 2014-07-22 Amdinocilina para la rápida determinación de la susceptibilidad a antibióticos beta-lactámicos. MX2016000811A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361857676P 2013-07-23 2013-07-23
PCT/US2014/047684 WO2015013324A1 (en) 2013-07-23 2014-07-22 Amdinocillin for rapid determination of susceptibility to beta-lactam antibiotics

Publications (1)

Publication Number Publication Date
MX2016000811A true MX2016000811A (es) 2016-10-13

Family

ID=52393790

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016000811A MX2016000811A (es) 2013-07-23 2014-07-22 Amdinocilina para la rápida determinación de la susceptibilidad a antibióticos beta-lactámicos.

Country Status (4)

Country Link
US (1) US20160160268A1 (es)
JP (1) JP6496727B2 (es)
MX (1) MX2016000811A (es)
WO (1) WO2015013324A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113943773A (zh) 2014-11-05 2022-01-18 加州理工学院 生物体对药物的响应的微流体测量
US9393243B1 (en) * 2015-07-14 2016-07-19 Nilesh Parikh Topical Ciprofloxacin compositions
KR101779038B1 (ko) 2016-03-31 2017-09-18 재단법인 한국파스퇴르연구소 황색포도상구균의 감수성 예측용 바이오마커 및 이의 용도
WO2018058078A1 (en) 2016-09-23 2018-03-29 California Institute Of Technology Digital quantification of dna replication and/or chromosome segregation based determination of antimicrobial susceptibility
SI3551293T1 (sl) * 2016-12-06 2022-06-30 Microbedx, Inc. RNAZA za izboljšano odkrivanje mikrobov in testiranje protimikrobne dovzetnosti
WO2019018692A1 (en) * 2017-07-19 2019-01-24 The Regents Of The University Of Colorado, A Body Corporate METHODS OF ASSESSING TREATMENT EFFICIENCY AND / OR TREATMENT DURATION IN MYCOBACTERIAL DISEASES
WO2019036715A1 (en) * 2017-08-18 2019-02-21 Microbedx, Inc. METHODS OF TESTING SENSITIVITY TO ANTIMICROBIAL AGENTS
US11827944B2 (en) 2017-10-11 2023-11-28 California Institute Of Technology Antibiotic susceptibility of microorganisms and related compositions, methods and systems
EP3794150A4 (en) * 2018-05-14 2022-04-13 MicrobeDx, Inc. METHODS FOR ESTIMATING MICROBIAL DENSITY IN SPECIMENS BY MEASUREMENT OF RIBOSOME RNA
WO2020028718A1 (en) * 2018-08-01 2020-02-06 California Institute Of Technology Antibiotic susceptibility of microorganisms and related markers, compositions, methods and systems
WO2020037202A1 (en) * 2018-08-17 2020-02-20 Genefluidics, Inc. Generation of data for use with antimicrobials

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712095A (en) * 1994-06-16 1998-01-27 Becton Dickinson And Company Rapid and sensitive detection of antibiotic-resistant mycobacteria using oligonucleotide probes specific for ribosomal RNA precursors
DE19731292A1 (de) * 1997-07-21 1999-01-28 Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh Nucleinsäuremolekül, Kit und Verwendung
WO2004038380A2 (en) * 2002-10-23 2004-05-06 Intronn, Inc. Screening methods for identification of efficient pre-trans-splicing molecules
WO2012027302A2 (en) * 2010-08-21 2012-03-01 The Regents Of The University Of California Systems and methods for detecting antibiotic resistance

Also Published As

Publication number Publication date
JP6496727B2 (ja) 2019-04-03
WO2015013324A1 (en) 2015-01-29
JP2016525357A (ja) 2016-08-25
US20160160268A1 (en) 2016-06-09

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