MX2015016143A - Peptidos de angiotensina para tratar el sindrome de marfan y transtornos relacionados. - Google Patents
Peptidos de angiotensina para tratar el sindrome de marfan y transtornos relacionados.Info
- Publication number
- MX2015016143A MX2015016143A MX2015016143A MX2015016143A MX2015016143A MX 2015016143 A MX2015016143 A MX 2015016143A MX 2015016143 A MX2015016143 A MX 2015016143A MX 2015016143 A MX2015016143 A MX 2015016143A MX 2015016143 A MX2015016143 A MX 2015016143A
- Authority
- MX
- Mexico
- Prior art keywords
- marfan
- marfan syndrome
- related disorders
- angiotensin
- related disorder
- Prior art date
Links
- 208000001826 Marfan syndrome Diseases 0.000 title abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 4
- 102000015427 Angiotensins Human genes 0.000 title 1
- 108010064733 Angiotensins Proteins 0.000 title 1
- 108010021281 angiotensin I (1-7) Proteins 0.000 abstract 2
- 230000003111 delayed effect Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/085—Angiotensins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
La presente invención proporciona, entre otras cosas, métodos para tratar el síndrome de Marfan y/o un trastorno relacionado con el síndrome de Marfan incluyendo la administración a un sujeto que padece o es susceptibles al síndrome de Marfan y/o un trastorno relacionado con el síndrome de Marfan, un péptído de angiotensina (1-7); en algunas modalidades, el péptido de angiotensina (1-7) se administra en una dosis eficaz de manera periódica en un intervalo de administración tal que al menos un síntoma o característica del síndrome de Marfan y/o un trastorno relacionado con el síndrome de Marfan es reducido en intensidad, severidad, duración o frecuencia o ha demorado su inicio.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361827271P | 2013-05-24 | 2013-05-24 | |
PCT/US2014/039141 WO2014190152A1 (en) | 2013-05-24 | 2014-05-22 | Angiotensin peptides in treating marfan syndrome and related disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2015016143A true MX2015016143A (es) | 2016-03-31 |
Family
ID=51934150
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015016143A MX2015016143A (es) | 2013-05-24 | 2014-05-22 | Peptidos de angiotensina para tratar el sindrome de marfan y transtornos relacionados. |
Country Status (11)
Country | Link |
---|---|
US (3) | US9107870B2 (es) |
EP (1) | EP3003345A4 (es) |
JP (1) | JP2016520592A (es) |
KR (1) | KR20160016872A (es) |
CN (1) | CN105451756A (es) |
AU (1) | AU2014268524A1 (es) |
BR (1) | BR112015028788A2 (es) |
CA (1) | CA2912635A1 (es) |
MX (1) | MX2015016143A (es) |
RU (1) | RU2015147241A (es) |
WO (1) | WO2014190152A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3350200A4 (en) | 2015-09-18 | 2019-03-27 | Wake Forest University Health Services | ANGIOTENSIN ANALOGUES (1-7) AND ASSOCIATED METHODS |
CA2914601A1 (en) * | 2015-12-11 | 2017-06-11 | Wake Forest University Health Sciences | Angiotensin-(1-7) analogs and methods relating thereto |
CN109666729A (zh) * | 2019-01-29 | 2019-04-23 | 四川省人民医院 | 一种马凡综合征筛查试剂盒 |
WO2024052343A1 (en) * | 2022-09-06 | 2024-03-14 | Institut National de la Santé et de la Recherche Médicale | Trem-2 agonists for the treatment of marfan syndrome |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4244946A (en) | 1979-06-11 | 1981-01-13 | The Salk Institute For Biological Studies | Water-soluble peptides affecting gonadal function |
US4305872A (en) | 1979-10-19 | 1981-12-15 | Kenneth Wingrove | Polypeptide derivatives |
US4316891A (en) | 1980-06-14 | 1982-02-23 | The Salk Institute For Biological Studies | Extended N-terminal somatostatin |
US5182264A (en) * | 1986-03-07 | 1993-01-26 | Schering Corporation | Angiotensin II receptor blockers as antiglaucoma agents |
US20020168761A1 (en) | 2000-01-24 | 2002-11-14 | Gour Barbara J. | Peptidomimetic modulators of cell adhesion |
EP0937103B1 (en) | 1996-07-12 | 2007-11-28 | McGILL UNIVERSITY | Compounds and methods for modulating cell adhesion |
YU78601A (sh) | 1999-05-05 | 2005-07-19 | Aventis Pharma Deutschland Gmbh. | 1-(p-tienilbenzil)-imidazoli kao agonisti angiotenzin-(1-7)- receptora, postupak za njihovu proizvodnju, njihova primena i farmaceutski preparati koji ih sadrže |
US20030078190A1 (en) * | 2001-05-25 | 2003-04-24 | Weinberg Marc S. | Methods for tissue protection using highly effective inhibition of the renin-angiotensin system |
ES2526705T3 (es) * | 2005-10-25 | 2015-01-14 | The Johns Hopkins University | Métodos y composiciones para el tratamiento de síndrome de Marfan y trastornos asociados |
WO2008130217A1 (en) * | 2006-08-08 | 2008-10-30 | Applied Nanosystems B.V. | Cyclic angiotensin analogs |
BRPI0800585B8 (pt) | 2008-02-13 | 2021-05-25 | Univ Minas Gerais | composições farmacêuticas do peptídeo des-[asp1]-[ala1]-angiotensina-(1-7) e uso do peptídeo des-[asp1]-[ala1]-angiotensina-(1-7) |
ES2393455T3 (es) * | 2008-09-12 | 2012-12-21 | Charité-Universitátsmedizin Berlin (Charité) | Uso de un agonista del receptor Ang-(1-7) en lesiones pulmonares agudas |
CL2008003736A1 (es) | 2008-12-15 | 2009-05-29 | Univ Pontificia Catolica Chile | Uso de angiotensina (1-9) para preparar un medicamento, util para prevenir, revertir y/o disminuir el remodelado cardiovascular, pulmonar, renal y/o cerebral. |
JP2014525439A (ja) * | 2011-08-30 | 2014-09-29 | メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ | ナトリウム利尿ポリペプチド |
WO2013090833A1 (en) * | 2011-12-16 | 2013-06-20 | Tarix Pharmaceuticals Ltd. | Angiotensins for treatment of fibrosis |
EP2819687A4 (en) * | 2012-02-10 | 2015-09-30 | Tarix Pharmaceuticals Ltd | COMPOSITIONS AND METHODS FOR TREATING PERIPHERAL VASCULAR DISEASE |
DK2967049T3 (da) * | 2013-03-15 | 2020-12-07 | Univ Southern California | Metoder, forbindelser og sammensætninger til behandlingen af angiotensin relaterede sygdomme |
-
2014
- 2014-05-22 JP JP2016515084A patent/JP2016520592A/ja active Pending
- 2014-05-22 EP EP14800387.4A patent/EP3003345A4/en not_active Withdrawn
- 2014-05-22 BR BR112015028788A patent/BR112015028788A2/pt not_active Application Discontinuation
- 2014-05-22 CA CA2912635A patent/CA2912635A1/en not_active Abandoned
- 2014-05-22 WO PCT/US2014/039141 patent/WO2014190152A1/en active Application Filing
- 2014-05-22 RU RU2015147241A patent/RU2015147241A/ru not_active Application Discontinuation
- 2014-05-22 MX MX2015016143A patent/MX2015016143A/es unknown
- 2014-05-22 AU AU2014268524A patent/AU2014268524A1/en not_active Abandoned
- 2014-05-22 CN CN201480041324.8A patent/CN105451756A/zh active Pending
- 2014-05-22 KR KR1020157036035A patent/KR20160016872A/ko not_active Application Discontinuation
- 2014-10-03 US US14/506,489 patent/US9107870B2/en not_active Expired - Fee Related
-
2015
- 2015-07-10 US US14/796,366 patent/US20160038560A1/en not_active Abandoned
-
2017
- 2017-04-03 US US15/478,040 patent/US20180050079A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2016520592A (ja) | 2016-07-14 |
CN105451756A (zh) | 2016-03-30 |
AU2014268524A1 (en) | 2015-12-03 |
US20160038560A1 (en) | 2016-02-11 |
KR20160016872A (ko) | 2016-02-15 |
US20180050079A1 (en) | 2018-02-22 |
US20150031634A1 (en) | 2015-01-29 |
RU2015147241A (ru) | 2017-06-29 |
BR112015028788A2 (pt) | 2017-09-19 |
US9107870B2 (en) | 2015-08-18 |
EP3003345A1 (en) | 2016-04-13 |
CA2912635A1 (en) | 2014-11-27 |
EP3003345A4 (en) | 2017-03-01 |
WO2014190152A1 (en) | 2014-11-27 |
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