MX2015012341A - Enriquecimiento de células tumorales circulantes por desgaste de glóbulos blancos. - Google Patents

Enriquecimiento de células tumorales circulantes por desgaste de glóbulos blancos.

Info

Publication number
MX2015012341A
MX2015012341A MX2015012341A MX2015012341A MX2015012341A MX 2015012341 A MX2015012341 A MX 2015012341A MX 2015012341 A MX2015012341 A MX 2015012341A MX 2015012341 A MX2015012341 A MX 2015012341A MX 2015012341 A MX2015012341 A MX 2015012341A
Authority
MX
Mexico
Prior art keywords
white blood
enrichment
cells
circulating tumor
blood cells
Prior art date
Application number
MX2015012341A
Other languages
English (en)
Other versions
MX365713B (es
Inventor
Brad Foulk
Galla Chandra Rao
Denis Smirnov
Karl Nielsen
Original Assignee
Janssen Diagnostics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Diagnostics Llc filed Critical Janssen Diagnostics Llc
Publication of MX2015012341A publication Critical patent/MX2015012341A/es
Publication of MX365713B publication Critical patent/MX365713B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/583—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención descrita incluye métodos y estuches para la remoción de glóbulos blancos de muestras de células extrañas enriquecidas.
MX2015012341A 2013-03-15 2014-03-14 Enriquecimiento de células tumorales circulantes por desgaste de glóbulos blancos. MX365713B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361787611P 2013-03-15 2013-03-15
PCT/US2014/027701 WO2014152758A1 (en) 2013-03-15 2014-03-14 Enrichment of circulating tumor cells by depleting white blood cells

Publications (2)

Publication Number Publication Date
MX2015012341A true MX2015012341A (es) 2016-06-06
MX365713B MX365713B (es) 2019-06-11

Family

ID=50631046

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015012341A MX365713B (es) 2013-03-15 2014-03-14 Enriquecimiento de células tumorales circulantes por desgaste de glóbulos blancos.

Country Status (20)

Country Link
US (2) US9823238B2 (es)
EP (1) EP2972359B1 (es)
JP (1) JP6563379B2 (es)
CN (1) CN105026934A (es)
AU (1) AU2014239168A1 (es)
BR (1) BR112015022962A2 (es)
CA (1) CA2906900A1 (es)
CY (1) CY1123698T1 (es)
DK (1) DK2972359T3 (es)
ES (1) ES2846224T3 (es)
HK (2) HK1216442A1 (es)
HR (1) HRP20201907T1 (es)
HU (1) HUE052519T2 (es)
LT (1) LT2972359T (es)
MX (1) MX365713B (es)
PL (1) PL2972359T3 (es)
PT (1) PT2972359T (es)
RS (1) RS61052B1 (es)
SI (1) SI2972359T1 (es)
WO (1) WO2014152758A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108061804B (zh) * 2016-11-09 2020-05-12 北京大学人民医院 用于诊断子宫内膜异位症的生物标志物
CN109991410B (zh) * 2017-12-29 2022-07-05 上海白泽医学检验所有限公司 一种含抗cd45单抗的组合物及其使用方法
CN109439732B (zh) * 2018-12-25 2024-04-12 迈迪速能医学技术（天津）有限公司 一种用于三维无创肿瘤早筛的试剂盒
US11890616B2 (en) 2019-03-26 2024-02-06 The Curators Of The University Of Missouri Microfluidic device for capture of micrometer scale objects and methods of using the device
KR102346111B1 (ko) * 2020-02-07 2022-01-03 주식회사 싸이토딕스 Ctc 분리용 마그네틱 비드 및 이를 이용한 ctc 분리방법
EP4208719A1 (en) * 2020-09-02 2023-07-12 Menarini Silicon Biosystems S.p.A. System, kit, method and process for handling a sample

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05501612A (ja) * 1989-11-13 1993-03-25 チルドレンズ・メデイカル・センター・コーポレーシヨン 胎児ｄｎａ単離および検出のための非侵入性方法
WO1999041613A1 (en) 1998-02-12 1999-08-19 Immunivest Methods and reagents for the rapid and efficient isolation of circulating cancer cells
US6342344B1 (en) * 1998-07-31 2002-01-29 Stemcell Technologies Inc. Antibody composition for isolating human cells from human-murine chimeric hematopoietic cell suspensions
US7364921B1 (en) * 1999-01-06 2008-04-29 University Of Medicine And Dentistry Of New Jersey Method and apparatus for separating biological materials and other substances
WO2001014591A1 (en) * 1999-08-21 2001-03-01 Fox John S High sensitivity biomolecule detection with magnetic particles
CN1871517A (zh) * 2002-02-19 2006-11-29 免疫公司 快速有效分离循环癌细胞的方法和试剂
CA2504279A1 (en) * 2005-04-15 2006-10-15 University Of Saskatchewan Materials and method of modulating the immune response using t helper-antigen presenting cells
US7901950B2 (en) 2005-08-12 2011-03-08 Veridex, Llc Method for assessing disease states by profile analysis of isolated circulating endothelial cells
EP2201134B1 (en) * 2007-09-19 2018-11-21 The Research Foundation of State University of New York Gene expression signatures in enriched tumor cell samples
JP5479355B2 (ja) 2007-11-27 2014-04-23 ベリデックス・エルエルシー 血液中の循環黒色腫細胞の自動計数及び特徴付け
US20090191535A1 (en) * 2007-12-22 2009-07-30 Mark Carle Connelly Method of assessing metastatic carcinomas from circulating endothelial cells and disseminated tumor cells
CN101469310B (zh) * 2007-12-28 2014-03-19 北京百奥科生物技术有限公司 从生物学样品富集靶细胞的方法及除去白细胞的方法
US8569077B2 (en) * 2008-05-19 2013-10-29 Veridex, Llc Imaging of immunomagnetically enriched rare cells
WO2011063416A2 (en) * 2009-11-23 2011-05-26 The General Hospital Corporation Microfluidic devices for the capture of biological sample components
CA2804914A1 (en) * 2010-07-22 2012-01-26 Nadir Askenasy Regulatory immune cells with enhanced targeted cell death effect
CN103826750B (zh) 2011-07-21 2020-11-10 詹森诊断器材有限责任公司 从血液中捕获和检测循环多发性骨髓瘤的测定法
US10420801B2 (en) * 2012-03-21 2019-09-24 The General Hospital Corporation Isolation and use of human lymphoid organ-derived suppressive stromal cells
US20140011685A1 (en) 2012-07-03 2014-01-09 Yixin Wang Genomic diagnostics using circulating endothelial cells

Also Published As

Publication number Publication date
US20180045712A1 (en) 2018-02-15
RS61052B1 (sr) 2020-12-31
PT2972359T (pt) 2020-10-29
DK2972359T3 (da) 2020-11-09
CA2906900A1 (en) 2014-09-25
WO2014152758A1 (en) 2014-09-25
EP2972359B1 (en) 2020-09-23
LT2972359T (lt) 2020-12-10
JP2016519286A (ja) 2016-06-30
JP6563379B2 (ja) 2019-08-21
CN105026934A (zh) 2015-11-04
HK1216442A1 (zh) 2016-11-11
EP2972359A1 (en) 2016-01-20
US10365266B2 (en) 2019-07-30
SI2972359T1 (sl) 2021-01-29
US20140335542A1 (en) 2014-11-13
CY1123698T1 (el) 2022-03-24
HUE052519T2 (hu) 2021-05-28
HK1219776A1 (zh) 2017-04-13
US9823238B2 (en) 2017-11-21
BR112015022962A2 (pt) 2017-07-18
AU2014239168A1 (en) 2015-10-29
MX365713B (es) 2019-06-11
PL2972359T3 (pl) 2021-03-08
HRP20201907T1 (hr) 2021-01-22
ES2846224T3 (es) 2021-07-28

Similar Documents

Publication Publication Date Title
DOP2018000181A (es) Terapias de combinación para enfermedades malignas hematológicas con anticuerpos anti-cd38 e inhibidores de survivina
EA202193044A2 (ru) Способы лечения таупатии
SG10201810108PA (en) Anti-b7-h1 and anti-ctla-4 antibodies for treating non-small cell lung cancer
EA202092987A2 (ru) Липид, содержащий докозапентаеновую кислоту
TW201613962A (en) Fabs-in-tandem immunoglobulin and uses thereof
NZ720949A (en) Methods and compositions for treating aging-associated conditions
PH12015501071A1 (en) Combination therapy of anti-her3 antibodies
MX2015012401A (es) Composiciones y metodos de alterar niveles de colesterol.
MX2015012326A (es) Anticuerpos anti-crth2 y su uso.
MY171473A (en) Antibodies to tau
CY1123698T1 (el) Εμπλουτισμος κυκλοφορουντων κυτταρων ογκου μεσω εξαντλησης λευκων αιμοσφαιριων
MX2013011479A (es) Anticuerpos anti-fgfr4 y metodos de uso.
EA201500943A1 (ru) Составы для мобилизации, хоуминга, размножения и дифференцировки стволовых клеток и способы применения составов
MX2016000997A (es) Metodos y composiciones para detectar contaminacion bacteriana.
IN2014DN05885A (es)
MX2014002053A (es) Anticuerpos anti -mcsp y metodos de uso.
MX2014004022A (es) Anticuerpos anti-htra1 y metodos de uso.
MX2014014376A (es) Anticuerpos de anti-biotina y metodos de uso.
MX2014014464A (es) Peptidos penetrantes de celulas y metodos para identificar peptidos penetrantes de celulas.
PH12017501864A1 (en) Compositions and methods for treating autism
MX2015009818A (es) Agonistas de receptores gamma activados por el proliferador de peroxisoma para el tratamiento de esclerosis multiple.
MX357675B (es) Anticuerpos anti-jagged y métodos de uso.
PH12016501326A1 (en) (s)-3'-methyl-abscisic acid and esters thereof
MX2014014443A (es) Agentes de ligacion a tlr3.
EA201590615A1 (ru) Стимулирующие лактацию композиции на основе фосфатидилсерина

Legal Events

Date Code Title Description
FG Grant or registration