MX2015000408A

MX2015000408A - Forma de triple sal de metformina.

Forma de triple sal de metformina.

Info

Publication number: MX2015000408A
Authority: MX; Mexico
Prior art keywords: metformin; compound; subject; formula; compound according
Prior art date: 2012-07-10

Application number

MX2015000408A

Other languages

English (en)

Spanish (es)

Inventor

Banavara L Mylari

Frank C Sciavolino

Original Assignee

Thetis Pharmaceuticals Llc

Priority date

2012-07-10

Filing date

2013-07-10

Publication date

2015-07-14

2013-03-15 Priority claimed from US13/841,970 external-priority patent/US8765811B2/en

2013-07-10 Application filed by Thetis Pharmaceuticals Llc filed Critical Thetis Pharmaceuticals Llc

2015-07-14 Publication of MX2015000408A publication Critical patent/MX2015000408A/es

Links

XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title claims abstract description 58
229960003105 metformin Drugs 0.000 title claims abstract description 47
150000001875 compounds Chemical class 0.000 claims abstract description 156
150000003839 salts Chemical class 0.000 claims abstract description 81
206010012601 diabetes mellitus Diseases 0.000 claims abstract description 73
JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims abstract description 44
MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims abstract description 33
229940000640 docosahexaenoate Drugs 0.000 claims abstract description 26
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CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims abstract description 11
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LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims description 28
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JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims description 16
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SARHCLAXCDURCW-RSDXMDNYSA-N 3-(diaminomethylidene)-1,1-dimethylguanidine;(5z,8z,11z,14z,17z)-icosa-5,8,11,14,17-pentaenoic acid Chemical compound CN(C)C(=[NH2+])NC(N)=N.CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC([O-])=O SARHCLAXCDURCW-RSDXMDNYSA-N 0.000 claims description 7
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