MX2014009835A - Animales transgénicos con características personalizables. - Google Patents

Animales transgénicos con características personalizables.

Info

Publication number
MX2014009835A
MX2014009835A MX2014009835A MX2014009835A MX2014009835A MX 2014009835 A MX2014009835 A MX 2014009835A MX 2014009835 A MX2014009835 A MX 2014009835A MX 2014009835 A MX2014009835 A MX 2014009835A MX 2014009835 A MX2014009835 A MX 2014009835A
Authority
MX
Mexico
Prior art keywords
transgenic animals
customizable traits
cassette
traits
black
Prior art date
Application number
MX2014009835A
Other languages
English (en)
Inventor
James West
Original Assignee
Mice With Horns Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mice With Horns Llc filed Critical Mice With Horns Llc
Publication of MX2014009835A publication Critical patent/MX2014009835A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/20—Animal model comprising regulated expression system
    • A01K2217/203—Animal model comprising inducible/conditional expression system, e.g. hormones, tet
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/20—Animal model comprising regulated expression system
    • A01K2217/206—Animal model comprising tissue-specific expression system, e.g. tissue specific expression of transgene, of Cre recombinase
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/02—Animal zootechnically ameliorated
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describen materiales y métodos para crear características a medida en animales; en la demostración del principio de la invención, un promotor específico de queratina 14 se utiliza con proteína flurorescente roja en el casete loxp, defensina beta negro dominante (?G23)103 en el casete de pigmento, y una secuencia de poliadenilación SV40 (con intrón); cuando se aplica la recombinasa Cre (o HTNCre) a la piel del animal en una base del portador (por ejemplo, bicapas de lípidos), la piel se modifica genéticamente de manera permanente para volverse negra en la forma en la que se aplicó.
MX2014009835A 2012-02-15 2013-02-15 Animales transgénicos con características personalizables. MX2014009835A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261598987P 2012-02-15 2012-02-15
PCT/US2013/026396 WO2013123365A1 (en) 2012-02-15 2013-02-15 Transgenic animals with customizable traits

Publications (1)

Publication Number Publication Date
MX2014009835A true MX2014009835A (es) 2014-12-08

Family

ID=48946802

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014009835A MX2014009835A (es) 2012-02-15 2013-02-15 Animales transgénicos con características personalizables.

Country Status (10)

Country Link
US (2) US20130212722A1 (es)
EP (1) EP2819509A4 (es)
JP (1) JP6282600B2 (es)
CN (1) CN104202970B (es)
AU (2) AU2013221342B2 (es)
BR (1) BR112014020089A2 (es)
CA (1) CA2864444A1 (es)
IN (1) IN2014DN07642A (es)
MX (1) MX2014009835A (es)
WO (1) WO2013123365A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2533629B1 (en) * 2010-02-11 2018-11-28 Recombinetics, Inc. Methods and materials for producing transgenic artiodactyls
US10920242B2 (en) 2011-02-25 2021-02-16 Recombinetics, Inc. Non-meiotic allele introgression
US9528124B2 (en) 2013-08-27 2016-12-27 Recombinetics, Inc. Efficient non-meiotic allele introgression
US10058078B2 (en) 2012-07-31 2018-08-28 Recombinetics, Inc. Production of FMDV-resistant livestock by allele substitution
BR112015023414A2 (pt) * 2013-03-15 2017-11-28 Aggenetics Inc animais transgênicos com características personalizáveis
US10779518B2 (en) 2013-10-25 2020-09-22 Livestock Improvement Corporation Limited Genetic markers and uses therefor
CN104805123B (zh) * 2015-05-22 2018-03-06 中国农业科学院特产研究所 一种鹿茸骨膜组织的转基因方法
CN106521638A (zh) * 2015-09-09 2017-03-22 潘雨堃 一种基因突变大鼠资源库及其制备方法
KR102033215B1 (ko) * 2016-07-05 2019-10-16 성균관대학교산학협력단 건선 유발 동물 모델 및 이의 용도
GB201619876D0 (en) 2016-11-24 2017-01-11 Cambridge Entpr Ltd Controllable transcription
CN106868044A (zh) * 2017-02-15 2017-06-20 扬州大学 一种转基因动物毛色报告基因表达盒、表达载体及应用
EP3653716A1 (en) * 2018-11-19 2020-05-20 HSF Pharmaceuticals Replication-competent controlled alpha-herpesvirus virus vectors and uses therefore
CN109680075B (zh) * 2019-01-11 2020-12-04 山东农业大学 一种基于基因型选择的比利时毛色家兔纯化方法
CN110878360A (zh) * 2019-11-06 2020-03-13 浙江万里学院 基于asp基因表达量差异鉴定清溪乌鳖品系和日本品系的方法
JP2023516484A (ja) 2020-03-11 2023-04-19 ビット バイオ リミテッド 肝細胞作製方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1280623A (zh) * 1997-11-26 2001-01-17 诺瓦提斯公司 用于激活沉默转基因的方法和物质
GB9926161D0 (en) * 1999-11-04 2000-01-12 Pig Improvement Company Uk Lim Methods
WO2002086098A2 (en) * 2001-03-05 2002-10-31 University Of Virginia Patent Foundation A lac operator-repressor system
EP2342343A2 (en) * 2008-09-05 2011-07-13 Aarhus Universitet Nuclear receptor sensor system in transgenic animal
CN101967187A (zh) * 2009-07-28 2011-02-09 中国科学院遗传与发育生物学研究所 一种与细胞应激相关的蛋白及其编码基因与应用

Also Published As

Publication number Publication date
AU2013221342B2 (en) 2018-10-04
IN2014DN07642A (es) 2015-05-15
JP2015507932A (ja) 2015-03-16
WO2013123365A1 (en) 2013-08-22
EP2819509A4 (en) 2015-10-07
AU2019200050A1 (en) 2019-01-24
EP2819509A1 (en) 2015-01-07
US20130212722A1 (en) 2013-08-15
CA2864444A1 (en) 2013-08-22
CN104202970A (zh) 2014-12-10
JP6282600B2 (ja) 2018-02-21
CN104202970B (zh) 2017-02-22
AU2013221342A1 (en) 2014-09-04
US10047376B2 (en) 2018-08-14
BR112014020089A2 (pt) 2017-07-04
US20130298268A1 (en) 2013-11-07

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