MX2014006990A - Tratamiento para diabetes tipo i y tipo ii. - Google Patents
Tratamiento para diabetes tipo i y tipo ii.Info
- Publication number
- MX2014006990A MX2014006990A MX2014006990A MX2014006990A MX2014006990A MX 2014006990 A MX2014006990 A MX 2014006990A MX 2014006990 A MX2014006990 A MX 2014006990A MX 2014006990 A MX2014006990 A MX 2014006990A MX 2014006990 A MX2014006990 A MX 2014006990A
- Authority
- MX
- Mexico
- Prior art keywords
- type
- diabetes
- treatment
- mammal
- effective amount
- Prior art date
Links
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 title abstract 2
- 208000001072 type 2 diabetes mellitus Diseases 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- -1 phenoxypyrimidinone compound Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención proporciona métodos para tratar diabetes tipo I o tipo II en un mamífero mediante la administración de una cantidad eficaz de insulina y una cantidad eficaz de un compuesto de fenoxipirimidinona al mamífero en necesidad de este tratamiento, y formulaciones para llevar a cabo los métodos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161569496P | 2011-12-12 | 2011-12-12 | |
PCT/US2012/069072 WO2013090319A2 (en) | 2011-12-12 | 2012-12-12 | Treatment of type i and type ii diabetes |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014006990A true MX2014006990A (es) | 2015-02-05 |
MX359171B MX359171B (es) | 2018-09-18 |
Family
ID=48613352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014006990A MX359171B (es) | 2011-12-12 | 2012-12-12 | Tratamiento para diabetes tipo i y tipo ii. |
Country Status (15)
Country | Link |
---|---|
US (2) | US20150190396A1 (es) |
EP (1) | EP2790704B1 (es) |
JP (1) | JP6152387B2 (es) |
KR (1) | KR102069395B1 (es) |
CN (2) | CN107007608B (es) |
AU (2) | AU2012352480A1 (es) |
BR (1) | BR112014014289A8 (es) |
CA (1) | CA2859156C (es) |
HK (1) | HK1202819A1 (es) |
IL (1) | IL233004B (es) |
MX (1) | MX359171B (es) |
RU (1) | RU2646475C2 (es) |
SG (2) | SG11201403207WA (es) |
WO (1) | WO2013090319A2 (es) |
ZA (1) | ZA201404738B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10863264B2 (en) | 2017-01-23 | 2020-12-08 | David Sampson | Vibration inducing tactile apparatus |
US11254645B2 (en) | 2018-01-11 | 2022-02-22 | Bukwang Pharmaceutical Co., Ltd. | Method for preparing tolimidone on large scale |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3922345A (en) | 1971-10-29 | 1975-11-25 | Pfizer | Pyrimidinones and hydroxy pyrimidines |
SE9203753D0 (sv) | 1992-12-11 | 1992-12-11 | Kabi Pharmacia Ab | Expression system for producing apolipoprotein ai-m |
SE9500778D0 (sv) | 1995-03-03 | 1995-03-03 | Pharmacia Ab | Process for producing a protein |
US6004925A (en) | 1997-09-29 | 1999-12-21 | J. L. Dasseux | Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
US6037323A (en) | 1997-09-29 | 2000-03-14 | Jean-Louis Dasseux | Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
US20030198666A1 (en) * | 2002-01-07 | 2003-10-23 | Richat Abbas | Oral insulin therapy |
US7985422B2 (en) * | 2002-08-05 | 2011-07-26 | Torrent Pharmaceuticals Limited | Dosage form |
US20070025953A1 (en) * | 2005-07-27 | 2007-02-01 | Jones Michael R | Co-therapy for diabetic conditions |
NZ565955A (en) * | 2005-08-22 | 2011-08-26 | Melior Pharmaceuticals I Inc | Methods and formulations for modulating lyn kinase activity and treating related disorders |
RU2316339C1 (ru) * | 2006-09-13 | 2008-02-10 | Общество С Ограниченной Ответственностью "Концерн О3" | Способ получения препарата инсулина для перорального применения |
KR20100014480A (ko) * | 2007-02-20 | 2010-02-10 | 멜리어 파마슈티칼스 아이, 인코포레이티드 | Lyn 키나제 활성제의 확인 방법 |
NZ579288A (en) * | 2007-07-23 | 2012-06-29 | Melior Discovery Inc | Methods of activating irs-1 and akt |
PT2355829E (pt) * | 2008-12-12 | 2015-02-20 | Poxel S A S | Combinação de insulina com derivados de triazina e suas utilizações para o tratar diabetes |
US20130158055A1 (en) * | 2010-05-28 | 2013-06-20 | Andrew G. Reaume | Prevention Of Pancreatic Beta Cell Degeneration |
NZ758966A (en) * | 2017-04-10 | 2024-08-30 | Board Of Supervisors Of Louisiana State Univ And Agricultural And Mechanical College | Treatment of adipocytes |
-
2012
- 2012-12-12 CA CA2859156A patent/CA2859156C/en active Active
- 2012-12-12 CN CN201610988112.1A patent/CN107007608B/zh active Active
- 2012-12-12 WO PCT/US2012/069072 patent/WO2013090319A2/en active Application Filing
- 2012-12-12 US US14/364,792 patent/US20150190396A1/en not_active Abandoned
- 2012-12-12 SG SG11201403207WA patent/SG11201403207WA/en unknown
- 2012-12-12 JP JP2014547360A patent/JP6152387B2/ja active Active
- 2012-12-12 EP EP12857229.4A patent/EP2790704B1/en active Active
- 2012-12-12 RU RU2014128528A patent/RU2646475C2/ru active
- 2012-12-12 AU AU2012352480A patent/AU2012352480A1/en not_active Abandoned
- 2012-12-12 MX MX2014006990A patent/MX359171B/es active IP Right Grant
- 2012-12-12 KR KR1020147019062A patent/KR102069395B1/ko active IP Right Grant
- 2012-12-12 CN CN201280069531.5A patent/CN104271140B/zh active Active
- 2012-12-12 SG SG10201604828QA patent/SG10201604828QA/en unknown
- 2012-12-12 BR BR112014014289A patent/BR112014014289A8/pt not_active Application Discontinuation
-
2014
- 2014-06-08 IL IL233004A patent/IL233004B/en unknown
- 2014-06-26 ZA ZA2014/04738A patent/ZA201404738B/en unknown
-
2015
- 2015-04-10 HK HK15103538.6A patent/HK1202819A1/xx unknown
-
2017
- 2017-07-07 AU AU2017204652A patent/AU2017204652B2/en active Active
-
2020
- 2020-01-08 US US16/737,200 patent/US20200215068A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2015513310A (ja) | 2015-05-07 |
SG11201403207WA (en) | 2014-09-26 |
CA2859156C (en) | 2020-10-06 |
CN104271140A (zh) | 2015-01-07 |
BR112014014289A2 (pt) | 2017-06-13 |
KR102069395B1 (ko) | 2020-01-22 |
EP2790704A4 (en) | 2015-09-02 |
HK1202819A1 (en) | 2015-10-09 |
US20200215068A1 (en) | 2020-07-09 |
RU2014128528A (ru) | 2016-02-10 |
US20150190396A1 (en) | 2015-07-09 |
RU2646475C2 (ru) | 2018-03-05 |
KR20140107416A (ko) | 2014-09-04 |
CN107007608A (zh) | 2017-08-04 |
NZ626495A (en) | 2016-03-31 |
CA2859156A1 (en) | 2013-06-20 |
IL233004A0 (en) | 2014-07-31 |
CN107007608B (zh) | 2021-04-23 |
IL233004B (en) | 2020-01-30 |
EP2790704B1 (en) | 2019-04-03 |
BR112014014289A8 (pt) | 2017-06-13 |
WO2013090319A2 (en) | 2013-06-20 |
SG10201604828QA (en) | 2016-07-28 |
JP6152387B2 (ja) | 2017-06-21 |
AU2017204652A1 (en) | 2017-07-27 |
EP2790704A2 (en) | 2014-10-22 |
AU2012352480A1 (en) | 2014-07-17 |
WO2013090319A3 (en) | 2014-12-04 |
MX359171B (es) | 2018-09-18 |
CN104271140B (zh) | 2016-11-23 |
AU2017204652B2 (en) | 2018-08-16 |
ZA201404738B (en) | 2016-10-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |