MX2013008188A - Composicion y metodo para tratar cancer. - Google Patents

Composicion y metodo para tratar cancer.

Info

Publication number
MX2013008188A
MX2013008188A MX2013008188A MX2013008188A MX2013008188A MX 2013008188 A MX2013008188 A MX 2013008188A MX 2013008188 A MX2013008188 A MX 2013008188A MX 2013008188 A MX2013008188 A MX 2013008188A MX 2013008188 A MX2013008188 A MX 2013008188A
Authority
MX
Mexico
Prior art keywords
composition
cancer
treating cancer
purified surface
excreted protein
Prior art date
Application number
MX2013008188A
Other languages
English (en)
Other versions
MX343266B (es
Inventor
Jonathan F Head
Robert L Elliott
Original Assignee
Oncbiomune L L C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncbiomune L L C filed Critical Oncbiomune L L C
Publication of MX2013008188A publication Critical patent/MX2013008188A/es
Publication of MX343266B publication Critical patent/MX343266B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001136Cytokines
    • A61K39/001139Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001136Cytokines
    • A61K39/00114Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/00118Cancer antigens from embryonic or fetal origin
    • A61K39/001182Carcinoembryonic antigen [CEA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001193Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; PAP or PSGR
    • A61K39/001194Prostate specific antigen [PSA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55522Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55522Cytokines; Lymphokines; Interferons
    • A61K2039/55527Interleukins
    • A61K2039/55533IL-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se describen composiciones farmacéuticas útiles como vacunas, las cuales contienen una superficie purificada o proteína excretada cualitativa o cuantitativamente asociada con un tipo de cáncer, al menos una interleucina (IL), y al menos un factor estimulante de colonia (CSF), en donde la superficie purificada o proteína excretada se proporciona en una cantidad suficiente para inducir una respuesta inmune en un individuo al que se le administra la composición. Dichas composiciones pueden ser utilizadas en métodos para el tratamiento de individuos que tienen cáncer, y para inducir una respuesta inmunoterapéutica en el mismo.
MX2013008188A 2011-01-13 2012-01-09 Composicion y metodo para tratar cancer. MX343266B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/005,993 US8647627B2 (en) 2011-01-13 2011-01-13 Composition for a cancer vaccine
PCT/US2012/020596 WO2012096870A1 (en) 2011-01-13 2012-01-09 Composition and method for treating cancer

Publications (2)

Publication Number Publication Date
MX2013008188A true MX2013008188A (es) 2013-12-02
MX343266B MX343266B (es) 2016-10-31

Family

ID=45532060

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013008188A MX343266B (es) 2011-01-13 2012-01-09 Composicion y metodo para tratar cancer.

Country Status (11)

Country Link
US (4) US8647627B2 (es)
EP (1) EP2663324B1 (es)
JP (2) JP6118730B2 (es)
CN (1) CN103458917B (es)
CA (1) CA2824347A1 (es)
EA (1) EA028081B1 (es)
ES (1) ES2637637T3 (es)
HK (1) HK1188566A1 (es)
MX (1) MX343266B (es)
UA (1) UA108779C2 (es)
WO (1) WO2012096870A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014096367A1 (en) * 2012-12-21 2014-06-26 Servicio Andaluz De Salud Expression of beta2-microglobulin as a prognostic marker for tumour immune escape and resistance to cancer immunotherapy and a diagnostic biomarker for patient selection for specific gene therapy
CN103864939A (zh) * 2014-03-26 2014-06-18 中国药科大学 mGM-CSF/βhCG融合蛋白及其制备方法和应用
RU2719586C9 (ru) * 2014-06-13 2020-05-21 Алдар БУРИНБАЙАР Пероральная композиция и способы иммунотерапии
US20190086419A1 (en) * 2016-03-09 2019-03-21 Cézanne S.A.S. Chromogranin a as a marker for bladder cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5478556A (en) * 1994-02-28 1995-12-26 Elliott; Robert L. Vaccination of cancer patients using tumor-associated antigens mixed with interleukin-2 and granulocyte-macrophage colony stimulating factor
CA2246708C (en) * 1996-02-16 2005-06-14 Biomira Usa Inc. Vaccine for b-cell malignancies
US7517952B1 (en) * 1997-02-25 2009-04-14 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
EP0974357A1 (en) 1998-07-16 2000-01-26 Schering-Plough Chemokines as adjuvants of immune response
IL150978A0 (en) * 2000-02-18 2003-02-12 New York Medical College Nitroacridine/tumor inhibitor compositions
US20060035375A1 (en) 2004-08-16 2006-02-16 Head Jonathan F Method for selectively culturing epithelial or carcinoma cells
US8435507B2 (en) 2004-08-19 2013-05-07 University Of Maryland Prostate-specific antigen-derived MHC class II restricted peptides and their use in vaccines to treat or prevent prostate cancer
US7919079B2 (en) * 2006-03-31 2011-04-05 Biosante Pharmaceuticals, Inc. Cancer immunotherapy compositions and methods of use
US10722562B2 (en) * 2008-07-23 2020-07-28 Immudex Aps Combinatorial analysis and repair

Also Published As

Publication number Publication date
MX343266B (es) 2016-10-31
CA2824347A1 (en) 2012-07-19
EP2663324B1 (en) 2017-05-24
EP2663324A1 (en) 2013-11-20
CN103458917B (zh) 2016-01-20
WO2012096870A1 (en) 2012-07-19
JP2017043635A (ja) 2017-03-02
EA028081B1 (ru) 2017-10-31
US20120282216A1 (en) 2012-11-08
JP2014502636A (ja) 2014-02-03
UA108779C2 (uk) 2015-06-10
HK1188566A1 (zh) 2014-05-09
US20160136269A1 (en) 2016-05-19
US8647627B2 (en) 2014-02-11
EA201370155A1 (ru) 2013-11-29
US20140112884A1 (en) 2014-04-24
JP6118730B2 (ja) 2017-04-19
CN103458917A (zh) 2013-12-18
US9211322B2 (en) 2015-12-15
ES2637637T3 (es) 2017-10-16
US20190167788A1 (en) 2019-06-06

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