MX2013003286A - Tableta de multiples capas de desintegracion oral y su elaboracion. - Google Patents

Tableta de multiples capas de desintegracion oral y su elaboracion.

Info

Publication number
MX2013003286A
MX2013003286A MX2013003286A MX2013003286A MX2013003286A MX 2013003286 A MX2013003286 A MX 2013003286A MX 2013003286 A MX2013003286 A MX 2013003286A MX 2013003286 A MX2013003286 A MX 2013003286A MX 2013003286 A MX2013003286 A MX 2013003286A
Authority
MX
Mexico
Prior art keywords
manufacture
layer
orally disintegrating
disintegrating tablet
tablet
Prior art date
Application number
MX2013003286A
Other languages
English (en)
Other versions
MX346452B (es
Inventor
Harry S Sowden
Frank J Bunick
Christopher E Szymczak
Leo B Kriksunov
Joseph R Luber
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/887,544 external-priority patent/US8871263B2/en
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Priority claimed from PCT/US2011/029155 external-priority patent/WO2012039788A1/en
Priority claimed from US13/052,316 external-priority patent/US20110318411A1/en
Publication of MX2013003286A publication Critical patent/MX2013003286A/es
Publication of MX346452B publication Critical patent/MX346452B/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/022—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space whereby the material is subjected to vibrations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/288—Compounds of unknown constitution, e.g. material from plants or animals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/027—Particular press methods or systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
    • B30B11/10—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable intermittently rotated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/34—Heating or cooling presses or parts thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0805—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
    • B29C2035/0861—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation using radio frequency

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Mechanical Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención presenta una tableta que contiene una primera capa y una segunda capa, en donde: (i) la primera capa incluye un agente farmacéuticamente activo y la composición de la primera capa es distinta a la composición de la segunda capa; (ii) la tableta tiene una densidad menor que aproximadamente 0.8 g/cc; y (iii) la tableta se desintegra en la boca al colocarla sobre la lengua en menos de aproximadamente 30 segundos.
MX2013003286A 2010-09-22 2011-03-21 Tableta de multiples capas de desintegracion oral y su elaboracion. MX346452B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12/887,544 US8871263B2 (en) 2009-09-24 2010-09-22 Manufacture of tablet in a die utilizing radiofrequency energy and meltable binder
US12/887,552 US9610224B2 (en) 2009-09-24 2010-09-22 Manufacture of tablet in a die utilizing powder blend containing water-containing material
PCT/US2011/029155 WO2012039788A1 (en) 2010-09-22 2011-03-21 Multi-layered orally disintegrating tablet and the manufacture thereof
US13/052,316 US20110318411A1 (en) 2010-06-24 2011-03-21 Multi-layered orally disintegrating tablet and the manufacture thereof

Publications (2)

Publication Number Publication Date
MX2013003286A true MX2013003286A (es) 2013-05-22
MX346452B MX346452B (es) 2017-03-17

Family

ID=45874495

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2013003287A MX343047B (es) 2010-09-22 2011-03-21 Fabricacion de formas de dosificacion de densidad variable con el uso de energia de radiofrecuencia.
MX2013003286A MX346452B (es) 2010-09-22 2011-03-21 Tableta de multiples capas de desintegracion oral y su elaboracion.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2013003287A MX343047B (es) 2010-09-22 2011-03-21 Fabricacion de formas de dosificacion de densidad variable con el uso de energia de radiofrecuencia.

Country Status (8)

Country Link
EP (2) EP2618812B1 (es)
KR (2) KR20130136464A (es)
CN (2) CN103140218A (es)
AU (2) AU2011306063B2 (es)
BR (2) BR112013006522A2 (es)
CA (2) CA2810623A1 (es)
MX (2) MX343047B (es)
RU (2) RU2013118328A (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105415737A (zh) * 2015-12-07 2016-03-23 无锡市医用仪表厂 一种气动式压药机
RU2627893C1 (ru) * 2016-09-20 2017-08-14 Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский институт овцеводства и козоводства" (ФГБНУ "ВНИИОК") Способ производства комбинированной антигельминтной таблетки с симбиотиком для лечения мелкого рогатого скота
CN106619129B (zh) * 2017-01-22 2022-08-23 扬州大学 一种口服速溶药片的加工装置及其方法
US10730236B2 (en) * 2017-08-02 2020-08-04 Ethicon Llc System and method for additive manufacture of medical devices
DE102017127452A1 (de) * 2017-11-21 2019-05-23 Lts Lohmann Therapie-Systeme Ag Wasserlösliche Polymerklebschichten
CN108357138B (zh) * 2018-05-22 2019-11-29 安徽康博特保健食品有限公司 一种制药用压片机
KR102120720B1 (ko) * 2018-07-16 2020-06-10 연성정밀화학(주) 날푸라핀 함유 구강붕해정
CN110539909B (zh) * 2019-09-29 2024-02-23 红云红河烟草(集团)有限责任公司 烟包烟支自动包装装置
KR102439494B1 (ko) 2020-09-16 2022-09-02 권우희 수목보호장치
EP4247331B1 (en) * 2020-11-18 2025-10-08 BioPharma Synergies, S. L. Orodispersible powder composition comprising an antihistamine compound
CN113244181B (zh) * 2021-04-28 2023-05-26 浙江工业大学 一种采用大光斑加热熔融配方粉末快速制备片剂的方法
CN113768038A (zh) * 2021-09-14 2021-12-10 江苏省协同医药生物工程有限责任公司 一种精准定量实验动物功能性饲料及制备方法与设备
CN113910417B (zh) * 2021-11-03 2023-01-06 武陟县虹桥碳素有限责任公司 一种单孔坩埚一体成型装置
CN114311794A (zh) * 2021-12-19 2022-04-12 株洲老工匠精密合金有限公司 一种用于硬质合金片生产的全自动压机
CN120287632B (zh) * 2025-06-09 2025-08-19 大同宇林德石墨新材料股份有限公司 一种石墨电极加工用成型设备
CN120422500B (zh) * 2025-07-04 2026-04-10 石棉县集能新材料有限公司 一种锂电池负极材料加工设备

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US4268465A (en) * 1978-01-27 1981-05-19 Massachusetts Institute Of Technology Method of accelerating the cooling of polymeric articles
JPS5967006A (ja) * 1982-10-08 1984-04-16 Hitachi Ltd タブレツト成形機
US5139407A (en) * 1989-09-01 1992-08-18 General Electric Company Apparatus for reducing thermoplastic material compression mold cycle time
EP0416791A2 (en) * 1989-09-08 1991-03-13 General Motors Corporation Method and apparatus for compression moulding with dielectric heating
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US5654003A (en) * 1992-03-05 1997-08-05 Fuisz Technologies Ltd. Process and apparatus for making tablets and tablets made therefrom
ATE260646T1 (de) * 1996-04-16 2004-03-15 Novartis Consumer Health Sa Schnell zerfallende orale dosierungsform
KR100377212B1 (ko) * 2000-08-22 2003-03-19 박충호 노화지연 떡 및 그 제조방법
US6767200B2 (en) * 2001-09-28 2004-07-27 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
CN101352421A (zh) * 2002-01-16 2009-01-28 贝林格尔英格海姆法玛两合公司 一种制备基本上非结晶形式的替米沙坦的方法
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Also Published As

Publication number Publication date
CA2810623A1 (en) 2012-03-29
RU2013118234A (ru) 2014-10-27
AU2011306064B2 (en) 2015-03-12
MX2013003287A (es) 2013-05-22
RU2578950C2 (ru) 2016-03-27
MX346452B (es) 2017-03-17
BR112013006522A2 (pt) 2016-07-12
EP2618812B1 (en) 2018-10-17
MX343047B (es) 2016-10-21
CN103140218A (zh) 2013-06-05
KR20130136464A (ko) 2013-12-12
AU2011306064A1 (en) 2013-02-28
CA2809050A1 (en) 2012-03-29
KR20130137633A (ko) 2013-12-17
EP2618995A1 (en) 2013-07-31
AU2011306063B2 (en) 2015-03-12
EP2618812A1 (en) 2013-07-31
HK1184111A1 (zh) 2014-01-17
CN103140346A (zh) 2013-06-05
BR112013006597A2 (pt) 2016-06-21
CN103140346B (zh) 2016-03-09
AU2011306063A1 (en) 2013-02-28
CA2809050C (en) 2018-09-11
RU2013118328A (ru) 2014-10-27

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