MX2009006699A - Composicion y metodo para preparar tabletas oralmente disgregantes que contienen una alta dosis de ingredientes farmaceuticamente activos. - Google Patents

Composicion y metodo para preparar tabletas oralmente disgregantes que contienen una alta dosis de ingredientes farmaceuticamente activos.

Info

Publication number
MX2009006699A
MX2009006699A MX2009006699A MX2009006699A MX2009006699A MX 2009006699 A MX2009006699 A MX 2009006699A MX 2009006699 A MX2009006699 A MX 2009006699A MX 2009006699 A MX2009006699 A MX 2009006699A MX 2009006699 A MX2009006699 A MX 2009006699A
Authority
MX
Mexico
Prior art keywords
orally disintegrating
disintegrating tablets
composition
api
active ingredients
Prior art date
Application number
MX2009006699A
Other languages
English (en)
Inventor
Stephen H Wu
Jae Han Park
Kevin M Holman
Glen A Bish
Donald G Krieger
Daniel S Ramlose
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of MX2009006699A publication Critical patent/MX2009006699A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Abstract

La presente invención se refiere a composiciones y a métodos mejorados para preparar tabletas oralmente disgretantes (COD). En un aspecto de la presente invención, la COD contiene además al menos un ingrediente activo farmacéutico (API). En otro aspecto de la presente invención, la COD contiene una concentración elevada de al menos un API. Específicamente, las COD descritas en esta invención que contienen una concentración elevada de API pueden contener hasta aproximadamente el 70% p/p de ingrediente activo farmacéutico en una dosis unitaria, mientras que al mismo tiempo exhiben los convenientes atributos de tiempo de disgregación rápido, dureza y friabilidad aceptables para atravesar envases tipo blíster o para ser embotellados y una sensación bucal aceptable.
MX2009006699A 2006-12-21 2007-12-20 Composicion y metodo para preparar tabletas oralmente disgregantes que contienen una alta dosis de ingredientes farmaceuticamente activos. MX2009006699A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US87638306P 2006-12-21 2006-12-21
US94820807P 2007-07-06 2007-07-06
US95263807P 2007-07-30 2007-07-30
PCT/US2007/026185 WO2008079343A2 (en) 2006-12-21 2007-12-20 Composition of and method for preparing orally disintegrating tablets containing a high dose of pharmaceutically active ingredients

Publications (1)

Publication Number Publication Date
MX2009006699A true MX2009006699A (es) 2009-06-30

Family

ID=39345530

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009006699A MX2009006699A (es) 2006-12-21 2007-12-20 Composicion y metodo para preparar tabletas oralmente disgregantes que contienen una alta dosis de ingredientes farmaceuticamente activos.

Country Status (6)

Country Link
US (1) US20100055179A1 (es)
EP (1) EP2101739A2 (es)
AU (1) AU2007338751A1 (es)
CA (1) CA2673458A1 (es)
MX (1) MX2009006699A (es)
WO (1) WO2008079343A2 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US20090208576A1 (en) 2006-03-31 2009-08-20 Gandhi Anilkumar S Orally Disintegrating Tablets
GB2495563B (en) * 2009-04-28 2014-12-03 Isp Investments Inc Co-processed excipient compositions
US20110097401A1 (en) 2009-06-12 2011-04-28 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
WO2018142296A2 (en) * 2017-02-01 2018-08-09 Zion Azar Systems methods devices apparatuses circuits and computer executable code for production and topical application of a therapeutic substance
WO2019147650A1 (en) * 2018-01-23 2019-08-01 Gila Therapeutics, Inc. Peptide yy pharmaceutical formulations, compositions, and methods

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CH658188A5 (de) * 1984-03-23 1986-10-31 Ciba Geigy Ag Lagerstabile schnellzerfallende pharmazeutische presslinge.
AU2636797A (en) * 1996-04-16 1997-11-07 Novartis Consumer Health S.A. Fast disintegrating oral dosage form
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US7815937B2 (en) * 1998-10-27 2010-10-19 Biovail Laboratories International Srl Quick dissolve compositions and tablets based thereon
WO2001012161A1 (en) * 1999-08-17 2001-02-22 Novartis Consumer Health S.A. Rapidly dissolving dosage form and process for making same
EP1244428A1 (en) * 1999-12-06 2002-10-02 Edward Mendell Co., Inc. Pharmaceutical superdisintegrant
US20030185886A1 (en) * 2000-05-26 2003-10-02 Hanmi Pharm. Co., Ltd. Process for the preparation of rapidly disintegrating tablet
US7927623B2 (en) * 2001-02-15 2011-04-19 Mitsubishi Tanabe Pharma Corporation Tablets quickly disintegrated in oral cavity
US6998139B2 (en) * 2001-03-15 2006-02-14 Astellas Pharma Inc. Bitterness-reduced intrabuccally quick disintegrating tablets and method for reducing bitterness
US7037524B2 (en) * 2001-10-03 2006-05-02 Herbalscience, Llc Oral delivery of a botanical
MXPA04004181A (es) * 2001-11-02 2005-01-25 Sandoz Ag Procedimiento para preparar composiciones de ribavirina de alta carga, de rapida disolucion.
SE0200154D0 (sv) * 2002-01-21 2002-01-21 Galenica Ab New process
US20030161875A1 (en) * 2002-02-27 2003-08-28 Deepak Murpani Fast dissolving tablets of cyclooxygenase-2 enzyme inhibitors
AU2003221326A1 (en) * 2002-03-06 2003-09-16 Kyowa Hakko Kogyo Co., Ltd. Tablets quickly disintegrating in oral cavity
WO2003096874A2 (en) * 2002-05-15 2003-11-27 Sun Pharmaceutical Industries Limited Coated sustained release tablets of a hygroscopic compound for once-a-day therapy
US20050215498A1 (en) * 2002-05-31 2005-09-29 Guenther Eissner Method for the protection of endothelial and epithclial cells during chemotherapy
JP2006509771A (ja) * 2002-11-25 2006-03-23 パーデュー・リサーチ・ファウンデイション マンノースをベースとした速溶性錠剤
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WO2007028247A1 (en) * 2005-09-09 2007-03-15 University Of Manitoba Fast-disintegrating epinephrine tablets for buccal or sublingual administration
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EP1908748A1 (en) * 2006-10-05 2008-04-09 Krka Process for the preparation of memantine and its hydrochloric acid salt form

Also Published As

Publication number Publication date
EP2101739A2 (en) 2009-09-23
CA2673458A1 (en) 2008-07-03
WO2008079343A3 (en) 2008-08-14
WO2008079343A2 (en) 2008-07-03
AU2007338751A1 (en) 2008-07-03
US20100055179A1 (en) 2010-03-04

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