MX2012003296A - Gotas oculares acuosas que contienen latanoprost, y metodo para inhibir la adsorcion de latanoprost a una resina. - Google Patents
Gotas oculares acuosas que contienen latanoprost, y metodo para inhibir la adsorcion de latanoprost a una resina.Info
- Publication number
- MX2012003296A MX2012003296A MX2012003296A MX2012003296A MX2012003296A MX 2012003296 A MX2012003296 A MX 2012003296A MX 2012003296 A MX2012003296 A MX 2012003296A MX 2012003296 A MX2012003296 A MX 2012003296A MX 2012003296 A MX2012003296 A MX 2012003296A
- Authority
- MX
- Mexico
- Prior art keywords
- latanoprost
- resin
- eye drops
- adsorption
- aqueous eye
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención provee una gota ocular acuosa que contiene latanoprost, la cual es una preparación en donde la disminución de una concentración efectiva de latanoprost debida a la adsorción a una resma es suprimida, y la estabilidad de latanoprost es mejorada; es también un objetivo de la presente invención proveer un método para suprimir la adsorción de latanoprost a una resma; la presente invención provee una gota ocular acuosa que contiene latanoprost, un agente tensoactivo, y un ácido mono- o di-carboxílico alifático que tiene un número de carbonos de 3 a 10 o una sal del mismo; además, la presente invención provee un método para suprimir la adsorción de latanoprost a una resma en una solución acuosa, que incluye la adición de un agente tensoactivo, y un ácido mono- o di-carboxílico alifático que tiene un número de carbonos de 3 a 10 o una sal del mismo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009216182 | 2009-09-17 | ||
PCT/JP2010/066263 WO2011034192A1 (ja) | 2009-09-17 | 2010-09-17 | ラタノプロストを含有する水性点眼剤、並びにラタノプロストの樹脂への吸着の抑制方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2012003296A true MX2012003296A (es) | 2012-04-20 |
Family
ID=43758789
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012003296A MX2012003296A (es) | 2009-09-17 | 2010-09-17 | Gotas oculares acuosas que contienen latanoprost, y metodo para inhibir la adsorcion de latanoprost a una resina. |
Country Status (8)
Country | Link |
---|---|
US (1) | US20120184552A1 (es) |
EP (1) | EP2478906A4 (es) |
JP (1) | JPWO2011034192A1 (es) |
CN (1) | CN102481301A (es) |
CA (1) | CA2773597A1 (es) |
MX (1) | MX2012003296A (es) |
RU (1) | RU2012115103A (es) |
WO (1) | WO2011034192A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG187770A1 (en) | 2010-08-12 | 2013-03-28 | Univ Nanyang Tech | A liposomal formulation for ocular drug delivery |
PL2887923T3 (pl) * | 2012-08-24 | 2023-08-14 | Sun Pharmaceutical Industries Limited | Preparat okulistyczny polioksylipidu lub polioksylowego kwasu tłuszczowego i leczenie chorób oczu |
US9968679B2 (en) | 2013-01-31 | 2018-05-15 | Senju Pharmaceutical Co., Ltd. | Clear aqueous solution |
US9956195B2 (en) | 2014-01-07 | 2018-05-01 | Nanyang Technological University | Stable liposomal formulations for ocular drug delivery |
EP2937076B1 (en) * | 2014-04-25 | 2019-09-11 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Eye drops containing prostaglandin and tyloxapol |
EP3145549A4 (en) * | 2014-05-23 | 2018-02-14 | Ocular Technologies Sàrl | Topical formulations and uses thereof |
WO2017094506A1 (ja) * | 2015-11-30 | 2017-06-08 | ロート製薬株式会社 | 眼科組成物 |
EP3423076B1 (en) | 2016-02-29 | 2024-04-17 | Sun Pharmaceutical Industries Limited | Topical cyclosporine-containing formulations and uses thereof |
US11331390B2 (en) | 2016-04-22 | 2022-05-17 | Rohto Pharmaceutical Co., Ltd. | Ophthalmic composition |
EP3446682B1 (en) * | 2016-04-22 | 2021-05-26 | Rohto Pharmaceutical Co., Ltd. | Ophthalmic composition |
EP3590515A4 (en) * | 2017-02-28 | 2020-12-23 | Kowa Company, Ltd. | DRUG PRODUCT |
WO2018181294A1 (ja) * | 2017-03-27 | 2018-10-04 | 興和株式会社 | 医薬製剤 |
US20180318319A1 (en) | 2017-05-04 | 2018-11-08 | Ocular Science, Inc. | Compositions and Methods for Treating Eyes and Methods of Preparation |
JP6931493B2 (ja) * | 2017-06-22 | 2021-09-08 | ヨンスン ファイン ケミカル カンパニー,リミテッド | 緑内障治療用点眼組成物 |
CN110031584A (zh) * | 2019-04-17 | 2019-07-19 | 银谷制药有限责任公司 | Hplc法测定鲑鱼降钙素喷鼻剂中苯扎氯铵含量的方法 |
US11071724B2 (en) | 2019-05-17 | 2021-07-27 | Ocular Science, Inc. | Compositions and methods for treating presbyopia |
JP2022120120A (ja) * | 2022-06-13 | 2022-08-17 | 東亜薬品株式会社 | 眼科用水性組成物及びプロスタグランジンF2α誘導体の含量の低下を抑制する方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0286903B2 (en) * | 1987-04-03 | 2000-03-29 | The Trustees Of Columbia University In The City Of New York | Use of a prostaglandin in combination with an adrenergic blocking agent for reduction of intraocular pressure |
EP0569046B1 (en) | 1988-09-06 | 2002-11-13 | Pharmacia Aktiebolag | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
US5510383A (en) | 1993-08-03 | 1996-04-23 | Alcon Laboratories, Inc. | Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension |
CN1124842C (zh) | 1997-11-05 | 2003-10-22 | 千寿制药株式会社 | 缓释滴眼剂 |
CN1146423C (zh) | 1998-07-14 | 2004-04-21 | 阿尔康实验室公司 | 前列腺素产品 |
JP3876355B2 (ja) | 2000-09-13 | 2007-01-31 | 参天製薬株式会社 | 点眼液 |
KR100437873B1 (ko) | 2001-05-08 | 2004-06-26 | 연성정밀화학(주) | 프로스타글란딘 유도체의 제조방법 및 그의 입체특이적출발물질 |
JP4092507B2 (ja) | 2003-07-31 | 2008-05-28 | 参天製薬株式会社 | プロスタグランジン含有製品 |
US20050049311A1 (en) * | 2003-09-03 | 2005-03-03 | Pharmacia & Upjohn Company | Medicinal products comprising prostaglandin compositions and methods of packaging such compositions |
JP4820648B2 (ja) * | 2003-12-02 | 2011-11-24 | 千寿製薬株式会社 | ロテプレドノールエタボネート水性懸濁液剤 |
JP2005263792A (ja) * | 2004-02-19 | 2005-09-29 | Santen Pharmaceut Co Ltd | 澄明なラタノプロスト点眼液 |
JP5247453B2 (ja) | 2005-10-10 | 2013-07-24 | ノバガリ ファルマ エスア | プロスタグランジン含有眼科用カチオン性水中油型エマルジョン |
EP2123278B1 (en) * | 2007-02-07 | 2013-01-09 | Teika Pharmaceutical Co., Ltd. | Eye drop preparation comprising latanoprost |
JP2009040727A (ja) | 2007-08-09 | 2009-02-26 | Towa Yakuhin Kk | ラタノプロストを有効成分とする安定な点眼液剤 |
JP5437581B2 (ja) | 2008-03-11 | 2014-03-12 | 豊興工業株式会社 | 油圧ユニット |
-
2010
- 2010-09-17 RU RU2012115103/15A patent/RU2012115103A/ru not_active Application Discontinuation
- 2010-09-17 EP EP10817305A patent/EP2478906A4/en not_active Withdrawn
- 2010-09-17 JP JP2011531991A patent/JPWO2011034192A1/ja not_active Withdrawn
- 2010-09-17 WO PCT/JP2010/066263 patent/WO2011034192A1/ja active Application Filing
- 2010-09-17 CN CN2010800405794A patent/CN102481301A/zh active Pending
- 2010-09-17 MX MX2012003296A patent/MX2012003296A/es not_active Application Discontinuation
- 2010-09-17 US US13/496,419 patent/US20120184552A1/en not_active Abandoned
- 2010-09-17 CA CA2773597A patent/CA2773597A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN102481301A (zh) | 2012-05-30 |
CA2773597A1 (en) | 2011-03-24 |
EP2478906A4 (en) | 2013-02-20 |
WO2011034192A1 (ja) | 2011-03-24 |
US20120184552A1 (en) | 2012-07-19 |
JPWO2011034192A1 (ja) | 2013-02-14 |
RU2012115103A (ru) | 2013-10-27 |
EP2478906A1 (en) | 2012-07-25 |
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Legal Events
Date | Code | Title | Description |
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FA | Abandonment or withdrawal |