MX2012000087A - Metodo cromatografico basado en gradiente no lineal preparativo y productos purificados del mismo. - Google Patents
Metodo cromatografico basado en gradiente no lineal preparativo y productos purificados del mismo.Info
- Publication number
- MX2012000087A MX2012000087A MX2012000087A MX2012000087A MX2012000087A MX 2012000087 A MX2012000087 A MX 2012000087A MX 2012000087 A MX2012000087 A MX 2012000087A MX 2012000087 A MX2012000087 A MX 2012000087A MX 2012000087 A MX2012000087 A MX 2012000087A
- Authority
- MX
- Mexico
- Prior art keywords
- linear gradient
- chromatographic method
- purified products
- gradient based
- based chromatographic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
- B01D15/166—Fluid composition conditioning, e.g. gradient
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
- B01D15/203—Equilibration or regeneration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente descripción proporciona un método para purificación de péptidos por técnicas cromatográficas. La metodología propuesta ayudará a resolver los problemas asociados en purificación de productos de proteína biológica que surgen de la industria de biotecnología en evolución.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1639CH2009 | 2009-07-09 | ||
PCT/IN2010/000459 WO2011021210A1 (en) | 2009-07-09 | 2010-07-08 | A preparative non-linear gradient based chromatographic method and purified products thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2012000087A true MX2012000087A (es) | 2012-02-28 |
Family
ID=43606703
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012000087A MX2012000087A (es) | 2009-07-09 | 2010-07-08 | Metodo cromatografico basado en gradiente no lineal preparativo y productos purificados del mismo. |
Country Status (13)
Country | Link |
---|---|
US (1) | US20120123089A1 (es) |
EP (1) | EP2451824A4 (es) |
JP (1) | JP2012532862A (es) |
KR (1) | KR20120044358A (es) |
CN (1) | CN102471367A (es) |
AU (1) | AU2010286059A1 (es) |
BR (1) | BRPI1016071A2 (es) |
CA (1) | CA2766571A1 (es) |
IL (1) | IL217323A0 (es) |
MX (1) | MX2012000087A (es) |
RU (1) | RU2489441C1 (es) |
SG (1) | SG176985A1 (es) |
WO (1) | WO2011021210A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112649537B (zh) * | 2015-04-28 | 2024-03-29 | 深圳翰宇药业股份有限公司 | 多肽混合物高效液相色谱分析方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK353781A (da) * | 1981-08-10 | 1983-02-11 | Novo Industri As | Fremgangsmaade til fremstilling af insulinderivater |
US5514646A (en) * | 1989-02-09 | 1996-05-07 | Chance; Ronald E. | Insulin analogs modified at position 29 of the B chain |
DE4028120C2 (de) * | 1990-09-05 | 1996-09-19 | Hoechst Ag | Verfahren zur Reinigung von Insulin und/oder Insulinderivaten |
DE19726167B4 (de) * | 1997-06-20 | 2008-01-24 | Sanofi-Aventis Deutschland Gmbh | Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung |
DE19838097A1 (de) * | 1998-08-24 | 2000-03-02 | Hoechst Marion Roussel De Gmbh | Verfahren zur chromatographischen Reinigung von Insulinen |
US6451987B1 (en) * | 1999-03-15 | 2002-09-17 | Novo Nordisk A/S | Ion exchange chromatography of proteins and peptides |
DE602005026182D1 (de) * | 2005-07-08 | 2011-03-10 | Biocon Ltd | Herstellung von insulinkonjugaten |
ES2546016T3 (es) * | 2005-10-13 | 2015-09-17 | Biocon Limited | Procedimiento para la preparación de conjugados de insulina |
CA2690564A1 (en) * | 2007-06-13 | 2008-12-24 | Sterrenbeld Biotechnologie North America, Inc. | Transgenic mammals that produce exogenous proteins in milk |
MY161892A (en) * | 2008-02-19 | 2017-05-15 | Biocon Ltd | A method of obtaining a purified, biologically active heterologous protein |
PT2464655T (pt) * | 2009-08-11 | 2017-05-25 | Biocon Ltd | Processos cromatográficos |
-
2010
- 2010-07-08 KR KR1020127003463A patent/KR20120044358A/ko not_active Application Discontinuation
- 2010-07-08 BR BRPI1016071A patent/BRPI1016071A2/pt not_active IP Right Cessation
- 2010-07-08 CN CN201080030652XA patent/CN102471367A/zh active Pending
- 2010-07-08 SG SG2011096021A patent/SG176985A1/en unknown
- 2010-07-08 MX MX2012000087A patent/MX2012000087A/es unknown
- 2010-07-08 JP JP2012519123A patent/JP2012532862A/ja active Pending
- 2010-07-08 RU RU2012102504/04A patent/RU2489441C1/ru not_active IP Right Cessation
- 2010-07-08 WO PCT/IN2010/000459 patent/WO2011021210A1/en active Application Filing
- 2010-07-08 EP EP10809642.1A patent/EP2451824A4/en not_active Withdrawn
- 2010-07-08 CA CA2766571A patent/CA2766571A1/en not_active Abandoned
- 2010-07-08 US US13/382,299 patent/US20120123089A1/en not_active Abandoned
- 2010-07-08 AU AU2010286059A patent/AU2010286059A1/en not_active Abandoned
-
2012
- 2012-01-02 IL IL217323A patent/IL217323A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA2766571A1 (en) | 2011-02-24 |
EP2451824A1 (en) | 2012-05-16 |
IL217323A0 (en) | 2012-02-29 |
US20120123089A1 (en) | 2012-05-17 |
KR20120044358A (ko) | 2012-05-07 |
SG176985A1 (en) | 2012-01-30 |
AU2010286059A1 (en) | 2012-02-02 |
BRPI1016071A2 (pt) | 2019-09-24 |
JP2012532862A (ja) | 2012-12-20 |
WO2011021210A1 (en) | 2011-02-24 |
CN102471367A (zh) | 2012-05-23 |
RU2489441C1 (ru) | 2013-08-10 |
EP2451824A4 (en) | 2013-04-24 |
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