EP2396399A4 - System and methods for purifying biological materials - Google Patents

System and methods for purifying biological materials

Info

Publication number
EP2396399A4
EP2396399A4 EP10741852.7A EP10741852A EP2396399A4 EP 2396399 A4 EP2396399 A4 EP 2396399A4 EP 10741852 A EP10741852 A EP 10741852A EP 2396399 A4 EP2396399 A4 EP 2396399A4
Authority
EP
European Patent Office
Prior art keywords
methods
biological materials
purifying biological
purifying
materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP10741852.7A
Other languages
German (de)
French (fr)
Other versions
EP2396399A2 (en
Inventor
Jeffrey L Helfer
Rhiannon R Gaborski
Maurice A Kildal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diffinity Genomics Inc
Original Assignee
Diffinity Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diffinity Genomics Inc filed Critical Diffinity Genomics Inc
Publication of EP2396399A2 publication Critical patent/EP2396399A2/en
Publication of EP2396399A4 publication Critical patent/EP2396399A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0275—Interchangeable or disposable dispensing tips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34—Purifying; Cleaning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/405—Concentrating samples by adsorption or absorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0631—Purification arrangements, e.g. solid phase extraction [SPE]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0609—Holders integrated in container to position an object
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4005—Concentrating samples by transferring a selected component through a membrane
    • G01N2001/4016—Concentrating samples by transferring a selected component through a membrane being a selective membrane, e.g. dialysis or osmosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1048—General features of the devices using the transfer device for another function
    • G01N2035/1053—General features of the devices using the transfer device for another function for separating part of the liquid, e.g. filters, extraction phase
EP10741852.7A 2009-02-14 2010-02-13 System and methods for purifying biological materials Withdrawn EP2396399A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15268009P 2009-02-14 2009-02-14
US29033309P 2009-12-28 2009-12-28
PCT/US2010/024201 WO2010093998A2 (en) 2009-02-14 2010-02-13 System and methods for purifying biological materials

Publications (2)

Publication Number Publication Date
EP2396399A2 EP2396399A2 (en) 2011-12-21
EP2396399A4 true EP2396399A4 (en) 2014-03-26

Family

ID=42562310

Family Applications (1)

Application Number Title Priority Date Filing Date
EP10741852.7A Withdrawn EP2396399A4 (en) 2009-02-14 2010-02-13 System and methods for purifying biological materials

Country Status (4)

Country Link
US (1) US20120071643A1 (en)
EP (1) EP2396399A4 (en)
CN (1) CN102439128A (en)
WO (1) WO2010093998A2 (en)

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US9242244B2 (en) * 2010-02-09 2016-01-26 Douglas T. Gjerde Method and apparatus for pipette tip columns
WO2012103214A2 (en) 2011-01-26 2012-08-02 Molecular Bioproducts, Inc. Magnetic pipette tip
US9404864B2 (en) 2013-03-13 2016-08-02 Denovo Sciences, Inc. System for imaging captured cells
US10466160B2 (en) 2011-08-01 2019-11-05 Celsee Diagnostics, Inc. System and method for retrieving and analyzing particles
CA2842359A1 (en) 2011-08-01 2013-02-07 Denovo Sciences Cell capture system and method of use
WO2013181019A1 (en) * 2012-05-31 2013-12-05 Siemens Healthcare Diagnostics Inc. Magnetic particle washing apparatus and method
WO2014026008A1 (en) * 2012-08-08 2014-02-13 Diffinity Genomics, Inc. Disposable functional pipette tips for the isolation of nucleic acids
SG11201404681VA (en) 2012-09-17 2014-09-26 Grace W R & Co Chromatography media and devices
US9606102B2 (en) 2013-01-26 2017-03-28 Denovo Sciences, Inc. System and method for capturing and analyzing cells
US10391490B2 (en) 2013-05-31 2019-08-27 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells
US10352954B2 (en) 2013-10-15 2019-07-16 Ecole Polytechnique Federale De Lausanne (Epfl) Sensing tip with electrical impedance sensor
US11389783B2 (en) 2014-05-02 2022-07-19 W.R. Grace & Co.-Conn. Functionalized support material and methods of making and using functionalized support material
CN107708862B (en) * 2015-03-06 2021-04-09 D·J·索尔 Method and apparatus for preparing and extracting biomolecules
JP6004149B1 (en) * 2015-03-16 2016-10-05 パナソニック株式会社 Pipette tips and pipetting methods
AU2016248031A1 (en) * 2015-04-15 2017-11-16 Ecole Polytechnique Federale De Lausanne (Epfl) Devices, systems and methods for dispensing and analysing particles
CN108064262B (en) * 2015-04-23 2021-08-31 Aj耶拿检疫有限公司 Nucleic acid extraction device and method
SG10201911134QA (en) 2015-06-05 2020-01-30 Grace W R & Co Adsorbent bioprocessing clarification agents and methods of making and using the same
WO2018075577A1 (en) * 2016-10-18 2018-04-26 President And Fellows Of Harvard College Methods of integrated microfluidic processing for preventing sample loss
TWI766942B (en) * 2017-02-13 2022-06-11 美商海科生醫有限責任公司 Apparatuses and methods for mixing fluid or media by vibrating a pipette using transient and steady-state intervals
CN106990193B (en) * 2017-04-28 2019-12-13 广东联捷生物科技有限公司 Pretreatment device and method for solid-phase extraction sample
CA3074461A1 (en) 2017-08-29 2019-03-07 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells
CN107446802A (en) * 2017-09-26 2017-12-08 深圳市百迈生命科学有限公司 A kind of micro 384 hole DNA synthesizing and purifying plates
CN208414415U (en) * 2018-03-13 2019-01-22 武汉医蒂生物科技有限公司 A kind of nucleic acid extraction Filter column
CN110272807B (en) * 2018-03-13 2020-11-24 武汉医蒂生物科技有限公司 Positive pressure device for nucleic acid extraction and purification
USD905865S1 (en) 2018-05-11 2020-12-22 Biotix, Inc. Pipette tip
JP6539774B1 (en) * 2018-05-11 2019-07-03 バイオティクス， インコーポレイテッド Pipette tip
US11701650B2 (en) * 2019-03-06 2023-07-18 Sergey Smulevitch Pipette tip containing one or more barriers
US10633693B1 (en) 2019-04-16 2020-04-28 Celsee Diagnostics, Inc. System and method for leakage control in a particle capture system
US11273439B2 (en) 2019-05-07 2022-03-15 Bio-Rad Laboratories, Inc. System and method for target material retrieval from microwells
CN110146341A (en) * 2019-05-30 2019-08-20 深圳市华星光电半导体显示技术有限公司 Auxiliary device and liquid crystal sampling system
CN114502250B (en) * 2019-08-13 2023-10-24 滴管公司 Methods and compositions for sample filtration
CN111272521B (en) * 2020-03-24 2020-12-29 中国水稻研究所 Pretreatment device and method for extracting and purifying ustilaginoidin A
CN113058672B (en) * 2021-04-15 2022-09-02 四川大学华西医院 Detachable pipettor with filtering device and manufacturing method thereof
WO2022226255A1 (en) * 2021-04-22 2022-10-27 Innovaprep Llc Prefilters for particle concentrators

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Publication number Priority date Publication date Assignee Title
US20020009809A1 (en) * 2000-02-09 2002-01-24 Brewer William E. Disposable pipette extraction
US20040072375A1 (en) * 2002-07-15 2004-04-15 Gjerde Douglas T. Low dead volume extraction column device
US6875354B1 (en) * 1997-02-26 2005-04-05 Millipore Corporation Cast membrane structures for sample preparation
US20060160122A1 (en) * 2004-02-18 2006-07-20 Applera Corporation Polyelectrolyte-coated size-exclusion ion-exchange particles
US20080287661A1 (en) * 2007-05-16 2008-11-20 Jones David C Devices and methods for reducing matrix effects

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DE3717211A1 (en) 1987-05-22 1988-12-01 Diagen Inst Molekularbio DEVICE AND METHOD FOR SEPARATING AND CLEANING MOLECULES
US6537502B1 (en) * 2000-07-25 2003-03-25 Harvard Apparatus, Inc. Surface coated housing for sample preparation
US8187557B2 (en) * 2006-07-13 2012-05-29 Cepheid Reagent reservoir system for analytical instruments

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6875354B1 (en) * 1997-02-26 2005-04-05 Millipore Corporation Cast membrane structures for sample preparation
US20020009809A1 (en) * 2000-02-09 2002-01-24 Brewer William E. Disposable pipette extraction
US20040072375A1 (en) * 2002-07-15 2004-04-15 Gjerde Douglas T. Low dead volume extraction column device
US20060160122A1 (en) * 2004-02-18 2006-07-20 Applera Corporation Polyelectrolyte-coated size-exclusion ion-exchange particles
US20080287661A1 (en) * 2007-05-16 2008-11-20 Jones David C Devices and methods for reducing matrix effects

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2010093998A2 *

Also Published As

Publication number Publication date
WO2010093998A3 (en) 2011-01-13
CN102439128A (en) 2012-05-02
EP2396399A2 (en) 2011-12-21
WO2010093998A2 (en) 2010-08-19
US20120071643A1 (en) 2012-03-22

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