MX2011012524A - Inhibidores de proteina cinasa c-met. - Google Patents

Inhibidores de proteina cinasa c-met.

Info

Publication number
MX2011012524A
MX2011012524A MX2011012524A MX2011012524A MX2011012524A MX 2011012524 A MX2011012524 A MX 2011012524A MX 2011012524 A MX2011012524 A MX 2011012524A MX 2011012524 A MX2011012524 A MX 2011012524A MX 2011012524 A MX2011012524 A MX 2011012524A
Authority
MX
Mexico
Prior art keywords
protein kinase
inhibitors
met protein
compounds
formula
Prior art date
Application number
MX2011012524A
Other languages
English (en)
Inventor
David Lauffer
Pan Li
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of MX2011012524A publication Critical patent/MX2011012524A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

.
MX2011012524A 2009-05-28 2010-05-27 Inhibidores de proteina cinasa c-met. MX2011012524A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18177809P 2009-05-28 2009-05-28
PCT/US2010/036329 WO2010138673A1 (en) 2009-05-28 2010-05-27 Inhibitors of c-met protein kinase

Publications (1)

Publication Number Publication Date
MX2011012524A true MX2011012524A (es) 2012-02-08

Family

ID=42591948

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011012524A MX2011012524A (es) 2009-05-28 2010-05-27 Inhibidores de proteina cinasa c-met.

Country Status (8)

Country Link
US (1) US8263776B2 (es)
EP (1) EP2435445A1 (es)
JP (1) JP2012528188A (es)
CN (1) CN102448969A (es)
AU (1) AU2010254063A1 (es)
CA (1) CA2762479A1 (es)
MX (1) MX2011012524A (es)
WO (1) WO2010138673A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130324526A1 (en) 2011-02-10 2013-12-05 Novartis Ag [1,2,4] triazolo [4,3-b] pyridazine compounds as inhibitors of the c-met tyrosine kinase
JP5957526B2 (ja) 2011-09-15 2016-07-27 ノバルティス アーゲー チロシンキナーゼとしての６−置換３−（キノリン−６−イルチオ）−［１，２，４］トリアゾロ［４，３−ａ］ピラジン
CN107666946A (zh) * 2015-05-26 2018-02-06 帝斯曼知识产权资产管理有限公司 通过sfc的手性异构体分离
US10344071B2 (en) 2015-07-28 2019-07-09 Musc Foundation For Research Development Identification of novel anti-fibrotic peptide in C-terminal region of the MET receptor tyrosine kinase
CN109897054B (zh) * 2017-12-08 2021-12-10 中国药科大学 三唑并噻二唑类c-Met激酶抑制剂的制备方法及其用途
CN111848580B (zh) * 2019-04-30 2021-09-14 武汉盛云生物医药科技有限责任公司 含1,2,4-三嗪-3,5-二酮的喹啉类化合物的晶型及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304121A (en) 1990-12-28 1994-04-19 Boston Scientific Corporation Drug delivery system making use of a hydrogel polymer coating
US5886026A (en) 1993-07-19 1999-03-23 Angiotech Pharmaceuticals Inc. Anti-angiogenic compositions and methods of use
US6099562A (en) 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
NZ555236A (en) * 2004-11-04 2010-10-29 Vertex Pharma Pyrazolo[1,5-a]pyrimidines useful as inhibitors of protein kinases
WO2007064797A2 (en) 2005-11-30 2007-06-07 Vertex Pharmaceuticals Incorporated Inhibitors of c-met and uses thereof
CN101360748B (zh) * 2005-11-30 2012-05-30 沃泰克斯药物股份有限公司 c-MET抑制剂及其应用
WO2007138472A2 (en) * 2006-05-30 2007-12-06 Pfizer Products Inc. Triazolopyridazine derivatives
EA200971077A1 (ru) * 2007-05-21 2010-04-30 ЭсДжиЭкс ФАРМАСЬЮТИКАЛЗ, ИНК. Гетероциклические модуляторы киназы
ES2393693T3 (es) * 2008-11-19 2012-12-27 Vertex Pharmaceuticals Incorporated Un derivado de triazolotiadiazol como inhibidor de la proteína-quinasa c-Met

Also Published As

Publication number Publication date
US8263776B2 (en) 2012-09-11
JP2012528188A (ja) 2012-11-12
CA2762479A1 (en) 2010-12-02
US20100305156A1 (en) 2010-12-02
CN102448969A (zh) 2012-05-09
WO2010138673A1 (en) 2010-12-02
AU2010254063A1 (en) 2011-12-01
EP2435445A1 (en) 2012-04-04

Similar Documents

Publication Publication Date Title
MX2009009590A (es) Aminopirimidinas utiles como inhibidores de proteinas cinasas.
UA115983C2 (uk) Інгібітори днк-пк
CA2818187C (en) Bromodomain inhibitors and uses thereof
IL200793A0 (en) Aminopyrimidines, compositions comprising the same and use thereof for inhibiting protein kinases
MX2009008253A (es) Derivados de 2-aminopiridina utiles como inhibidores de cinasa.
MX350761B (es) Inhibidores de isoindolinona de fosfatidilinositol 3-cinasa.
MX2009009592A (es) Aminopiridinas utiles como inhibidores de proteinas cinasas.
MX2009010037A (es) Aminopirimidinas utiles como inhibidores de cinasas.
UA105911C2 (uk) Сульфонамідні похідні
GEP20146102B (en) Compounds and compositions as protein kinase inhibitors
MX365294B (es) Inhibidores de proteína cinasa dependiente de adn.
NO20084435L (no) C-MET proteinkinaseinhibitorer
MX2012000709A (es) Inhibidores de pirrolopiridina de cinasas.
UA98373C2 (ru) Конденсированные гетероциклические производные и их применение как c-met ингибиторов
GEP20135785B (en) Pyrrolopyrimidine compounds as cdk inhibitors
MX336051B (es) Diarilacetileno hidracido que contiene inhibidores de tirosina quinasa.
MX2009006345A (es) Compuestos utiles como inhibidores de proteina cinasa.
MX2009011811A (es) Aminopirimidinas utiles como inhibidores de cinasa.
WO2010011772A3 (en) Tri-cyclic pyrazolopyridine kinase inhibitors
MX2013004298A (es) Derivados de quinazolin-4 (3h)-ona utilizados como inhibidores de pi3 cinasa.
MX2011013032A (es) Inhibidores de fosfatidilinositol 3-cinasa.
TN2014000016A1 (en) 4 - piperidinyl compounds for use as tankyrase inhibitors
MX2011009033A (es) Inhibidores triciclicos de cinasa pirazolopiridina.
MX2010003563A (es) Inhibidores de proteina cinasa de c-met.
MX2011006006A (es) Compuestos, composicion farmaceutica y metodos para utilizarse en el tratamiento de trastornos metabolicos.

Legal Events

Date Code Title Description
FA Abandonment or withdrawal